Abstract:
Objective
To analyze the clinical characteristics of refractory Mycoplasma pneumoniae pneumonia(RMPP) and general Mycoplasma pneumoniae pneumonia(GMPP) and investigate its high risk factors in order to provide a certain theoretical basis for early detection, early diagnosis, and early intervention of RMPP.
Methods
A total of 203 MMP children treated in Dalian Children's Hospital from October 2016 and September 2017 were chosen as the subjects, of whom there were 70 cases of RMPP and 133 cases of GMPP. The two groups of children were compared in clinical manifestation, imaging results and laboratory indicators, and the multifactor regression analysis was made.
Results
There was statistical difference between RMPP group and GMPP group in age of onset, fever duration, fever peak value, fever interval, proportion of symptoms complicating fever, length of hospital stay and the proportion of extrapulmonary complications(P<0.01). The level of serum Creactive protein and lactate dehydrogenase(LDH) was significantly higher in RMPP group than in GMPP group(P<0.01). There was no difference in WBC count or serum procalcitonin between the two groups(P>0.05). The proportion of children whose imaging shower to be lobar pneumonia and the proportion of children complicated with pleural effusion were significantly higher in RMPP group than in GMPP group, while the proportion of bronchopneumonia was significantly lower(P<0.01). The high risk factors of RMPP were fever duration, fever interval, symptoms complicating fever(being chilly, chills, etc.) and length of hospital stay.
ConclusionThe longer the fever duration and the length of hospital stay, the shorter the fever interval, and the more symptoms complicating fever, the more probable the children get RMPP.

Key words: Refractory Mycoplasma pneumoniae pneumonia, Clinical features, Children