Abstract: Primary nephrotic syndrome (PNS) is one of the most common glomerular diseases in children.Long-term oral glucocorticoids are recognized as the first-line treatment for PNS.Long-term use of glucocorticoids can lead to eye damage such as high eye pressure,glaucoma and cataracts.This article reviews the epidemiology,risk factors,pathogenesis,diagnosis,clinical manifestations,clinical management and treatment of glucocorticoid-induced eye damage in PNS.By establishing early screening,early diagnosis and early treatment of eye damage in PNS children during long-term glucocorticoid therapy,we hope to effectively ensure children′s eye health.

Key words: Primary nephrotic syndrome, Glucocorticoid, Eye damage, Children