ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2022, Vol. 14 ›› Issue (1): 16-20.doi: 10.3969/j.issn.1674-3865.2022.01.005

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Clinical study on treating bronchial asthma at chronic persistent phase in children with Yiqi Huanxiao decoction

LI Dongnan, WANG Hai, XING Xinxin, LIU Bonan, WANG Shengnan   

  1. The First Clinical Medical College,Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China

  • Received:2021-03-08 Published:2022-02-25 Online:2022-02-25
  • Contact: WANG Hai,E-mail:wanghai576@163.com

Abstract: Objective To observe the clinical effect of Yiqi Huanxiao decoction on bronchial asthma at chronic persistent phase in children and to explore its effectiveness.Methods Totally 120 children with chronic persistent Qi-deficiency and phlegm-stasis syndrome of bronchial asthma were randomly divided into experimental group and control group,with 60 in each group.The control group was treated with nebulized budesonide combined with montelukast sodium chewable tablets.The experimental group was treated with Yiqi Huanxiao decoction.Record and compare asthma symptom score,C-ACT score,lung function index,serum immunoglobulin level,lung HRCT mosaic sign score,and carry out the statistical analysis.Results There were 7 cases in each group which were lost to follow.The total effective rate in the experimental group was 94.34%(50/53),higher than that in the control group (81.14%,43/53),and the difference was of statistical significance (P<0.05).The asthma symptom score,C-ACT score,FEV1/FVC index,serum immunoglobulin IgA,IgG and IgM level,and lung HRCT mosaic score were significantly lower than those before treatment,and the experimental group was significantly lower than the control group,the difference being statistically significant (P<0.05).Conclusion The treatment with Yiqi Huanxiao decoction for bronchial asthma at chronic persistent phase in children is superior to traditional western medicine,which has clinical popularization value.

Key words:

Bronchial asthma, Chronic persistent phase, Qi-deficiency and phlegm-stasis syndrome, Children