ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2019, Vol. 11 ›› Issue (6): 509-511.

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Clinical analysis of immunoglobulin and complement changes in children infected with EB virus

  

  • Published:2019-12-25 Online:2023-12-06

Abstract:

ObjectiveTo analyze the changes of immunoglobulin and complement in children infected with EB virus. MethodsFrom January 1, 2017 to June 1, 2019, 100 children with EBV infection were treated in Shenyang Children's Hospital, and they were selected as the study subjects (the observation group), and 100 healthy children were selected as the control group at the same time. The complement level and serum immunoglobulin level of children in the two groups were detected by scatter turbidimetry, and the levels of C4, C3, IgE, IgA, IgM, IgG, CD56+, CD19+, CD4+, CD3+ were compared. ResultsThere was no significant difference in IgA between the observation group and the control group(P>0.05); C4, C3, IgE, IgM and IgG in the observation group were significantly higher than those in the control group(P<0.05). CD56+, CD19+ and CD3+ in the observation group were significantly higher than those in the control group, while CD4+ was significantly lower than that in the control group(P<0.05).ConclusionEpstein-Barr virus infection is closely related to immunoglobulin in children, and is significantly related to the decrease of CD4+.

Key words:

EBV infection, Immunoglobulin, Complement change, child