Abstract:

Based on the principle of orderliness and principle of functionality in systematic Chinese medicine, this paper discusses the pathogenesis and treatment of obesity combined with precocious puberty in children. The human body is a typical dissipative structure which regulates itself and resists "entropy increase" through constantly eliminating accumulated entropy inside and acquiring negative entropy from the outside, that is, the movement of qi, in order to, maintain the "dynamic balance of Yin and Yang" of the body. If the qi transformation of this dissipative structure (the human body) is abnormal, entropy change will be unbalanced, and the human body will be in a disordered and unstable state of "entropy increase". If "accumulated entropy" persists for a long time, it will lead to "entropy disease". Childhood obesity combined with precocious puberty belongs to "broad entropy disease", that is, a disease caused by the decline in the orderliness of life movement. The pathogenesis of obesity combined with precocious puberty in children can be divided into three types: spleen deficiency and loss of circulation lead to the production of phlegm, resulting in prolonged stagnation and accumulated entropy; liver depression leads to blood stasis and fat, and the release of entropy is blocked; there is congenital deficiency of essence and energy, along with a shortage of negative entropy sources. The treatments respectively focus on: regulating, transporting and transforming to regulate the liver and spleen in order to reduce entropy increase; nourishing, reducing and purifying to calm the heart and kidney in order to promote negative entropy; conducting overall syndrome differentiation to restore the order and balance the entropy. This article combines traditional Chinese medicine theory with entropy disease theory, highlights the unique advantages of the holistic concept of traditional Chinese medicine in the prevention and treatment of modern pediatric diseases from the perspective of "regulating the function of dissipative structure", reveals the nature of childhood obesity combined with precocious puberty, which is "imbalance of the body's orderliness", and elaborates on the pathogenesis evolution of childhood obesity combined with precocious puberty from the perspective of entropy disease, aiming to open up the treatment ideas for this disease.

Key words: Obesity, Precocious puberty, Entropy disease theory, Systematic Chinese medicine, Principle of orderliness, Principle of functionality, Child