小儿推拿联合运脾方治疗厌食症患儿的疗效观察

doi:10.20274/j.cnki.issn.1674-3865.2026.04.015

Abstract

Abstract:

Objective To observe the clinical efficacy of paediatric Tuina combined with the Yunpi formula in the treatment of children with anorexia. Methods A total of 112 children with anorexia admitted to the Paediatric Department of Pingdingshan Hospital of Traditional Chinese Medicine between April 2023 and June 2025 were selected and randomly divided into an observation group and a control group, each comprising 56 cases. Children in the control group were treated with oral bifidobacterium quadruple live bacteria tablets. Children in the observation group received treatment combining acupoint Tuina with the Yunpi formula. After 4 weeks of continuous treatment, the clinical efficacy, TCM syndrome scores, gastrointestinal hormone levels, D-xylose levels, appetite factor levels and adverse reactions were compared between the two groups. Results The overall effective rate in the observation group was 96.43%(54/56), which was higher than that in the control group (83.93%, 47/56), and the difference was statistically significant(P<0.05). After treatment, the TCM syndrome scores(loss of appetite, aversion to food, epigastric fullness and distension, belching and nausea, irregular bowel movements, and postprandial epigastric and abdominal distension) in the observation group were all lower than before treatment, and the observation group's scores were lower than those of the control group; all differences were statistically significant(P<0.05). After treatment, the levels of gastrointestinal hormones(serum gastrin, motilin) and D-xylose in the observation group were higher than before treatment, and the observation group was higher than the control group, with all differences being statistically significant(P<0.05). The level of the appetite factor neuropeptide Y after treatment in the observation group was higher than that before treatment, and the observation group's level was higher than that of the control group, with statistically significant differences(P<0.05). The level of the appetite factor leptin after treatment in the observation group was lower than that before treatment, and the observation group's level was lower than that of the control group, with statistically significant differences(P<0.05). No significant adverse reactions were observed in either group. Conclusion The combination of paediatric Tuina with Yunpi formula demonstrates significant efficacy in the treatment of children with anorexia. It effectively reduces the traditional Chinese medicine syndrome scores, improves gastrointestinal hormone levels, intestinal absorption and appetite factor levels, and is very safe.

Key words: Anorexia, Tuina, Yunpi formula, Traditional Chinese medicine syndrome score, Child

CLC Number:

R442.1

Huanhuan ZHANG, Jun LI, Cancan XU, Wanyue CHEN. Efficacy observation of pediatric Tuina combined with Yunpi formula in the treatment of children with anorexia[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(4): 348-352.

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References 30

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组别	n	性别（男/女，n）	年龄（x±s，岁）	病程（x±s，月）	体质量（x±s，kg）	病因（n）
组别	n	性别（男/女，n）	年龄（x±s，岁）	病程（x±s，月）	体质量（x±s，kg）	喂养不当	情志失调
对照组	56	31/25	3.41±0.57	5.79±1.63	15.44±1.67	31	25
观察组	56	33/23	3.59±0.60	5.90±1.84	14.86±1.82	34	22

组别	n	痊愈	有效	无效	总有效
对照组	56	17（30.36）	30（53.57）	9（16.07）	47（83.93）
观察组	56	36（64.29）	18（32.14）	2（3.57）	54（96.43）

组别	n	食欲不振		厌恶进食		胸脘痞闷
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	56	2.68±0.47	1.42±0.38^a	1.89±0.33	0.97±0.22^a	1.58±0.38	0.88±0.20^a
观察组	56	2.70±0.45	0.72±0.21^a	1.95±0.36	0.64±0.17^a	1.63±0.35	0.39±0.08^a
t值		0.230	12.065	0.919	8.882	0.724	17.023
P值		0.819	<0.001	0.360	<0.001	0.470	<0.001
组别	n	嗳气泛恶		大便不调		食后脘腹饱胀
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	56	1.70±0.43	1.08±0.29^a	1.48±0.29	1.06±0.18^a	2.04±0.55	1.47±0.38^a
观察组	56	1.78±0.41	0.75±0.12^a	1.44±0.31	0.77±0.13^a	2.10±0.48	1.05±0.29^a
t值		1.008	7.868	0.705	9.774	0.615	6.575
P值		0.316	<0.001	0.482	<0.001	0.540	<0.001

组别	n	胃泌素（ng/L）		胃动素（ng/L）		D-木糖（μmol/L）
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	56	21.36±4.73	46.79±5.88^a	182.17±17.84	248.02±13.82^a	0.51±0.09	0.62±0.17^a
观察组	56	22.49±5.01	63.28±6.07^a	180.03±19.57	301.38±10.86^a	0.49±0.10	0.84±0.24^a
t值		1.227	14.602	0.605	22.718	1.112	5.598
P值		0.222	<0.001	0.547	<0.001	0.268	<0.001

组别	n	神经肽Y		瘦素
组别	n	治疗前	治疗后	治疗前	治疗后
对照组	56	16.48±2.18	20.73±2.24^a	49.28±5.18	35.34±4.37^a
观察组	56	15.97±2.73	26.46±2.53^a	48.07±4.94	27.61±4.01^a
t值		1.092	12.689	1.265	9.753
P值		0.277	<0.001	0.209	<0.001

Efficacy observation of pediatric Tuina combined with Yunpi formula in the treatment of children with anorexia

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