Abstract: Objective:To analyze the relationship between risk factors and prognosis of febrile seizures in children.Methods:Totally 120 cases of children with febrile seizures who were admitted to Hunan Children's Hospital from August 2013 to August 2015 were studied. The relationship of prognosis with first-onset age, initial body temperature, family history and disease history was analyzed.Results:The follow up time was 3 to 6 years, averaged (4.8±1.1)years. Among 120 children with febrile seizures, the prognosis was poor in 14 cases(11.7%). The electroencephalogram confirmed that 10 cases were converted to epilepsy and 4 cases were determined to have intelligence disorder. The risk factors of febrile seizures included first-onset age, initial temperature, family history and disease history, and the differences were statistically significant among groups(P<0.05). Logistic regression analysis suggested that the independent risk factors affecting the prognosis of children with febrile seizures were first onset age <1 year, initial body temperature <40 ℃, disease history, and family history.Conclusion:The risk factors such as first-onset age, initial temperature, family history and history of febrile seizures were closely related to prognosis.

Key words: Febrile seizures, Risk factors, Prognosis, Children