ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (6): 625-627.doi: 10.3969/j.issn.1674-3865.2016.06.025

• 临床研究 • 上一篇    下一篇

婴幼儿血清铁蛋白检测在营养性缺铁性贫血中的临床应用

刘兰香,祝兴元,郑素平,刘云花   

  1. 410007 长沙,湖南省儿童医院核医学科
  • 出版日期:2016-12-25 发布日期:2018-11-19
  • 通讯作者: 祝兴元,E-mail:13908470687@163.com
  • 作者简介:刘兰香(1981-),女,主管技师。研究方向:儿童内分泌激素的临床项目检测

Clinical application of serum ferritin detection in children with nutritional iron deficiency anemia

LIU Lanxiang,ZHU xingyuan, ZHENG Suping, LIU Yunhua   

  1. Hunan Children's Hospital,Changsha 410007,China
  • Online:2016-12-25 Published:2018-11-19

摘要: 目的:观察婴幼儿血清铁蛋白测定在营养性缺铁性贫血中的应用。
方法:2013年1月至2016年1月在湖南省儿童医院儿童保健科正常体检的缺铁性贫血婴幼儿2 896例。按年龄分为3组,6个月至1岁组1 092例,>1~2岁组980例,>2~3岁组824例。检测不同年龄段婴幼儿血清铁蛋白水平及不同年龄段铁减少、缺铁性贫血和铁缺乏症检出情况。
结果:6~12个月和>1~2岁婴幼儿血清铁蛋白水平较>2~3岁显著偏低,差异有统计学意义(P<0.01);6~12个月婴幼儿血清铁蛋白水平与>1~2岁比较差异无统计学意义(P>0.05)。2 896例中铁减少457例(15.8%),缺铁性贫血437例(15.1%),铁缺乏症801例(27.7%)。6~12个月和>1~2岁婴幼儿铁减少检出率显著高于>2~3岁,差异有统计学意义(P<0.017);6~12个月婴幼儿铁减少检出率与>1~2岁比较差异无统计学意义(P>0.017)。随着年龄的增长缺铁性贫血和铁缺乏症检出率逐渐减低,不同年龄段间两两比较差异均有统计学意义(P<0.017)。
结论:6个月至3岁婴幼儿中普遍存在铁缺乏现象,为提高家长对婴幼儿铁减少和缺铁性贫血的及早预防,降低贫血的发生,应将血清铁蛋白检测作为婴幼儿期常规体检项目,从而指导家长为婴幼儿及时添加辅食,做到合理膳食,以防止营养性缺铁性贫血的发生。

关键词: 缺铁性贫血, 血清铁蛋白, 婴幼儿

Abstract: Objective:To study the application of serum ferritin detection in children with nutritional iron deficiency anemia.
Methods:From Jan.2013 to Jan.2016, a total of 2 896 children were found to be with iron deficiency anemia on routine physical examination in Hunan Children's Hospital. These children were divided into 3 groups according to their age: 6 months to 1 year old in group A(1 092 children),1 to two years old in group B(980 children),2 to 3 years old in group C(824 children).Detect serum level of ferritin in these children. The cases of iron decrease, iron deficiency anemia and iron deficiency were also detected.
Results:The serum level of ferritin in group A and group B was significantly lower than group C, there being statistical difference(P<0.01),but there was no statistical difference between group A and group B(P>0.05). There were 457 cases(15.8%) of iron decrease, 437 cases(15.1%) of iron deficiency anemia and 801 cases(27.7%) of iron deficiency. The detection rate of iron decrease in group A and B was significantly higher than in group C, and there was statistical difference(P<0.05), but there was no difference between group A and group B(P>0.05).With the child growing up, the detection rate of iron deficiency anemia and iron deficiency decreased gradually, and comparing any two groups among the 3 groups, there was statistical difference(P<0.05).
Conclusion:Iron deficiency is quite common in children between 6 months and 3 years old. In order to enhance parents' understanding about the early prevention of iron decrease and iron deficiency anemia and reduce the occurrence of anemia, the serum ferritin detection should be included in the routine physical examinations, and thus the parents can be taught to add solid food in time and to give balanced diet, achieving the aim of preventing nutritional iron deficiency anemia.

Key words: Iron deficiency anemia, Serum ferritin, Children