ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (3): 316-318.doi: 10.3969/j.issn.1674-3865.2016.03.023

• 临床研究 • 上一篇    下一篇

早期持续微量喂养与常规间断喂养对低出生体重儿营养状况的影响

刘大鹏，郭静，王颖源，康文清，张耀东，熊虹   

  1. 450000 郑州，郑州市儿童医院新生儿重症监护室
  • 出版日期:2016-06-25 发布日期:2018-11-19
  • 通讯作者: 熊虹，E-mail: xionghong57@126.com
  • 作者简介:刘大鹏(1978-)，男，主治医师。研究方向：新生儿重症疾病的诊治

Effect of early continuous microfeeding and routine intermittent feeding on the nutritional status of low-birth-weight infants

LIU Dapeng，GUO Jing，WANG Yingyuan，KANG Wenqing，ZHANG Yaodong，XIONG Hong   

  1. Neonatal Intensive Care Unit, Zhengzhou Children's Hospital, Zhengzhou 450000，China.
  • Online:2016-06-25 Published:2018-11-19

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摘要：
目的: 观察早期持续微量喂养与常规间歇喂养在低出生体重儿中的效果。
方法: 2014年8月至2015年8月郑州市儿童医院新生儿重症监护室收治低出生体重儿124例，随机分为观察组和对照组各62例。对照组给予常规间歇喂养，观察组采用早期持续微量喂养。观察两组患儿治疗前后体质量变化和血清胃泌素变化情况|观察两组患儿体质量开始增长时间、自行吮吸时间、黄疸消退时间和喂养并发症发生情况。
结果: 观察组干预后体质量为(1 673.54±154.27)g，胃泌素(124.82±14.28)ng/L，显著高于对照组干预后体质量(1 395.77±102.54)g，胃泌素(98.79±6.88)ng/L，差异有统计学意义(P<0.05)。观察组体质量开始增长时间、自行吮吸时间、黄疸消退时间、喂养并发症发生率均优于对照组，差异有统计学意义(P<0.05)。
结论: 采用早期持续微量喂养应用在低出生体重儿中能够提高喂养耐受性，促进胃肠道组织成熟，增长体质量快，缩短黄疸持续时间，值得在临床上推广应用。

关键词: 低出生体重儿, 早期, 持续微量喂养, 间断喂养, 营养状况

Abstract:
Objective: To observe the effect of early continuous microfeeding and routine intermittent feeding in low-birth-weight infants.
Methods: From August 2014 to August 2015, in Zhengzhou Children's Hospital Neonatal Intensive Care Unit, 124 cases of low-birth-weight infants were randomly divided into observation group and control group, each with 62 cases. The control group was given routine intermittent feeding, and the observation group was treated with early continuous microfeeding. The changes of body mass and serum gastrin were observed before and after treatment in two groups. The time for body mass to begin to increase, the time of self sucking, the regression time of jaundice and the incidence of feeding complications were also observed.
Results: In observation group the body mass after intervention was (1 673.54±154.27)g and gastrin was (124.82±14.28)ng/L, significantly higher than the control group, whose body mass was (1 395.77±102.54)g and gastrin was (98.79±6.88)ng/L, the difference being of statistical significance(P<0.05). The time for body mass to begin to increase self sucking time, jaundice subsiding time and feeding complication rate in the observation group were better than those of the control group, the difference being statistically significant(P<0.05).
Conclusion: The early microfeeding in low-birth-weight infants can improve the feeding tolerance, promote the maturation of the gastrointestinal tract, increase body weight rapidly, and shorten the duration of jaundice, which is worthy of being popularized in clinics.

Key words: Low-birth-weight infant, Early stage, Continuous microfeeding, Intermittent feeding, Nutritional status