ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2009, Vol. 1 ›› Issue (3): 213-216.doi: 10.3969/j.issn.16743865.2009.03.004

• 论著 • 上一篇    下一篇

嗽宁口服液的镇咳、祛痰及平喘作用的实验研究

刘曦,宋铁玎   

  1. 110032 沈阳,辽宁中医药大学研究生学院(刘曦);辽宁中医药大学附属医院儿科(宋铁玎)
  • 出版日期:2009-06-25 发布日期:2019-06-12
  • 通讯作者: 宋铁玎(1956-),男,教授、主任医师,硕士研究生导师。研究方向:中西医结合儿科
  • 作者简介:刘曦(1982-),女,辽宁中医药大学研究生学院2007级硕士研究生。研究方向:中医治疗反复呼吸道感染。

Experiment study on the antitussive,eliminating phlegm and antiasthmatic action of Souning oral

LIU Xi,SONG Tieding.   

  1. Graduate College,Liaoning University of TCM,Shenyang 110032,China
  • Online:2009-06-25 Published:2019-06-12

摘要: 目的观察嗽宁口服液的镇咳、祛痰及平喘作用。
方法采用豚鼠枸橼酸引咳实验、小鼠SO2引咳实验、小鼠酚红法祛痰实验、乙酰胆碱组胺豚鼠引喘实验、卵白蛋白豚鼠引喘实验方法进行嗽宁口服液镇咳、祛痰及平喘作用的研究。
结果嗽宁口服液在豚鼠枸橼酸引咳实验及小鼠SO2引咳实验中表现出显著的镇咳作用,在小鼠酚红法祛痰实验中祛痰作用显著,对乙酰胆碱、组织胺引喘实验豚鼠及卵白蛋白引喘实验豚鼠具有显著的平喘作用。
结论嗽宁口服液的中医处方具有镇咳、祛痰及平喘的功效。

关键词: 嗽宁口服液;咳嗽/治疗;祛痰;喘/治疗;动物, 实验

Abstract: ObjectiveTo study the antitussive,eliminating phlegm and antiasthmatic effects of Souning oral liquid.MethodsSome experiments were done,including cough induced by citric acid in guinea pigs,cough induced by SO2 in mice,expectorant tests by phenol red in mice,asthma induced by histamine and acetylcholine in guinea pigs,asthma induced by ovalbumin in guinea pig,to study the antitussive,eliminating phlegm and antiasthmatic effects of Souning oral liquid.ResultsSouning oral liquid exhibited significant effects in the tests of cough induced by citric acid,cough induced by SO2,expectorant tests by phenol red,asthma induced by histamine and acetylcholine,and asthma induced by ovalbumin.ConclusionThe study suggests that Souning oral liquid has  antitussive,eliminating phlegm and antiasthmatic effects.

Key words: Souning oral liquid, Cough/Treatment, Eliminating phlegm, Asthma/Treatment, Animal,experiment