ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (3): 241-246.doi: 10.3969/j.issn.1674-3865.2023.03.014

• 调查研究 • 上一篇    下一篇

特发性中枢性性早熟女童的生活质量及影响因素调查

付小平, 吴亚莉, 丁大为   

  1. 410007长沙，湖南省儿童医院儿童保健所（付小平，吴亚莉），儿童健康所（丁大为）
  • 收稿日期:2023-02-08 出版日期:2023-06-25 上线日期:2023-06-25
  • 通讯作者: 丁大为，E-mail：16337111@qq.com

Investigation of quality of life and influencing factors in girls with idiopathic central precocious puberty

FU Xiaoping, WU Yali, DING Dawei   

  1. Hunan Children′s Hospital，Changsha 410007，China
  • Received:2023-02-08 Published:2023-06-25 Online:2023-06-25
  • Contact: DING Dawei，E-mail：16337111@qq.com

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摘要： 目的 了解特发性中枢性性早熟女童的生活质量现状，分析其影响因素。方法 研究设计为成组病例对照研究。病例组为2021年6月至2022年11月湖南省某三级甲等儿童医院确诊的135例特发性中枢性性早熟女童。对照组为同期长沙市内某两所小学就读的182例正常发育的女童。应用一般资料问卷、儿童生存质量普适性量表(PedsQLTM4.0)进行调查。结果 病例组儿童PedsQLTM4.0总分、生理功能得分、情感功能得分、社交功能得分、学校表现得分均高于对照组，差异均有统计学意义(P<0.05)。多元回归分析显示，药物治疗疗程、家庭月收入、照顾者职业类型、医保、初复诊均是特发性中枢性性早熟女童的生活质量的影响因素。结论 特发性中枢性性早熟女童的生活质量较低，医护人员应加强关注，提高其生活质量。

关键词: 性早熟, 女童, 生活质量

Abstract: Objective To investigate the quality of life of girls with idiopathic central precocious puberty and analyze its influencing factors.
MethodsThe study was designed as a cluster case-control study.The case group was made up of 135 girls with idiopathic central precocious puberty confirmed in a tertiary A children′s hospital in Hunan Province from June 2021 to November 2022.The control group was made up of 182 girls with normal development attending two primary schools in Changsha during the same period.The general information questionnaire,the Universal Child Quality of Life Scale (PedsQLTM4.0) were used for investigation.Results The total scores of PedsQLTM4.0,physiological function score,emotional function score,social function score,and school performance score of the children in the case group were higher than those in the control group,and the differences were statistically significant (P<0.05).Multiple regression analysis showed that the course of drug treatment,monthly household income,type of caregiver′s occupation,medical insurance,and initial follow-up were all influencing factors of the quality of life of girls with idiopathic central precocious puberty.Conclusion Girls with idiopathic central precocious puberty have a low quality of life,and medical staff should pay more attention in order to improve their quality of life.


Key words: Precocious puberty, Girls, Quality of life