粪菌移植治疗儿童神经发育障碍性疾病的研究进展

doi:10.20274/j.cnki.issn.1674-3865.2025.01.005

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2025, Vol. 17 ›› Issue (1): 22-26.doi: 10.20274/j.cnki.issn.1674-3865.2025.01.005

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Research advances in the treatment of neurodevelopmental disorders in children with fecal microbiota transplantation

HUA Zhichao¹,CHEN Yuyan²，YANG Yufang²，CHEN Xiaoling³

¹The First Clinical Medical School of Zhejiang Chinese Medical University, Hangzhou 310053, China；²The First Affiliated Hospital of Zhejiang Chinese Medical University，Hangzhou 310006, China；³Traditional Chinese Medicine Hospital of Fenghua District of Ningbo City，Ningbo 315599, China

Received:2024-07-29 Revised:2024-09-01 Published:2025-02-25 Online:2025-02-25
Contact: CHEN Yuyan，E-mail：chyuyan@163.com
Supported by:
Zhejiang Province Traditional Chinese Medicine Science and Technology Plan（No.2024ZR084）

Abstract

Abstract: Fecal microbiota transplantation (FMT), as a method to treat intestinal and extra-intestinal diseases by regulating intestinal flora dysbiosis, has attracted widespread attention in recent years. Its effect in the treatment of children's neurodevelopmental disorders (NDDs) has gradually been verified, showing great application prospects, which provides new strategies for the treatment of NDDs. This article explores its clinical efficacy, development prospects and some technical limitations that still exist at present by summarizing the relevant animal and clinical studies on FMT treatment for NDDs, aiming to provide relevant references for the subsequent clinical treatment of NDDs.

Key words: Neurodevelopmental disorders, Fecal microbiota transplantation, Gut microbiota, Child

HUA Zhichao, CHEN Yuyan, YANG Yufang, CHEN Xiaoling. Research advances in the treatment of neurodevelopmental disorders in children with fecal microbiota transplantation[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(1): 22-26.

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Research advances in the treatment of neurodevelopmental disorders in children with fecal microbiota transplantation

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