新生儿肠外营养相关性胆汁淤积危险因素分析

doi:10.3969/j.issn.1674-3865.2009.04.003

Abstract

Abstract: Objective：To analyze the risk factors of parenteral nutritionassociated cholestasis（PNAC) in high-risk neonates.Methods：A total of 116 cases who had accepted parenteral nutrition during the neonatal period for at least 14 days were included in this study.The risk factors of PNAC were analyzed.Results：The incidence of PNAC was 26.7%.Gestational age,birth weight,persistence time in PN and infection were all closely correlated with PNAC.The pesistance time in PN was an independent risk factor of PNAC.Conclusion：The longer the persistence time,the more risk of happening of PNAC.Early enteral feeding and shortening the time of PN are the important measures to lower the incidence of PNCA.

Key words: Infant,newborn/disease, Parenteral nutrition, Cholestasis, Pneumonia, Hyaline membrane disease in neonates

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