Abstract:
Objective：To investigate the current situation of cytomegalovirus infection of hospitalized children in the northwest areas of the city.
Methods：Totally 5245 cases of children with suspected cytomegalovirus infection admitted to Fuyong People's Hospital of Baoan District, Songgang People's Hospital of Baoan District, and People's Hospital of Guangming New District in the northwest areas of the city from July 2013 to June 2015 were investigated by CMV infection survey. Blood specimens were taken to perform CMVIgG and CMVIgM antibody detection.
Results：Among the 5245 cases of hospitalized children with suspected cytomegalovirus infection, there were 733 cases confirmed with cytomegalovirus infection and the infection rate was 14.0% (733/5245), of which 37.5% (275/733) was primary infection and 62.5% (458/733) was active infection. There were certain differences in the incidence rates of clinical manifestations, such as jaundice, liver function damage, pneumonia and blood system and the differences were statistically significant (P＜0.05). In 733 cases of infected children, the infected female was significantly more than the infected male (P＜0.05).
Conclusion：The infection rate of cytomegalovirus infection in hospitalized children in the northwest areas of Shenzhen is about 14.0%. The infection rate of the female is higher than that of the male and the main clinical manifestations are different in patients of different age.

Key words: Cytomegalovirus infection, Investigation, Immunity, Children