Objective:To observe the clinical therapeutic effect of probiotics and gastrointestinal mucosal protective agents on antibiotic-associated diarrhea in children.

Methods:A total of 160 cases of children with antibiotic-associated diarrhea were divided into control group and observation group,each group with 80 cases,according to odd or even number of clinical visits.Both groups were given montmorillonite powder,and the observation group was added Bifid Triple Viable tablets taken orally,the dosage varying with different ages.The treatment stopped when the diarrhea stopped.After treatment,compare the time for fever to recede,the time for diarrhea to stop,the time for bowel movement to return normal,the clinical effect and the adverse reactions between the two groups.

Results:The total effective rate of the observation group was better than that of the control group,the difference being of statistical significant(P<0.05).Concerning the time of the abatement of fever,the time for diarrhea to stop,and the time for bowel movement to return normal,the observation group was better than the control group,and the difference was statistical(P<0.05).No adverse reaction was observed in the two groups.

Conclusion：The effect of Bifid Triple Viable tablets combined with montmorillonite powder is better than that of single use of montmorillonite,and the combination use should be popularized clinically.