Abstract:
Objective: To study the endoscopic and clinical features of Henoch-Schonlein purpura(HSP) in children with digestive tract symptoms.
Methods: Analyze the clinical features of 215 children with HSP in our hospital and summarize endoscopic results of 119 children who took gastroscopy. According to severity of mucosa damage under endoscopy, the children were divided into two groups. The total time of abdominal pain, the time of abdominal pain after admission, the hospital stay, the rate of pancreatitis and HSPN were compared between the two groups, and the high risk factors of severe mucosal damage were analyzed.
Results: The major digestive clinical manifestations of HSP were abdominal pain, emesia and hematochezia; abdominal pain was found as the first-onset symptom in 90 cases (41.9%). No significant difference was observed in the total time of abdominal pain and rate of pancreatitis between the two groups(P＞0.05). Significant differences was observed in the time of abdominal pain after admission, the hospital stay and the rate of HSPN between the two groups (P＜0.05). The rate of renal damage was of statistical significance in the risk factors of HSP children with severe digestive mucosa damage.
Conclusion: Abdominal pain can be the first-onset symptom. The endoscopic results of HSP in children can help to make the diagnosis. The severity of mucosa damage under endoscopy of HSP in children is not correlated with the total time of abdominal pain or the rate of pancreatitis, but is significantly correlated with the time of abdominal pain after admission, the hospital stay and the rate of HSPN. The risk factor associated with severe mucosa damage in HSP is renal damage.

Key words: Henoch-Schonlein purpura, Endoscopy, Gastrointestinal mucosal damage, Children