ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2017, Vol. 9 ›› Issue (2): 103-105.doi: 10.3969/j.issn.1674-3865.2017.02.004

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Influence of minimally invasive embedder wire on serum immunoglobulin and plate activating factor of children with cough variant asthma

JIN Jichao   

  1. Pediatric Department of Zhengzhou TCM Hospital, Zhengzhou 457000, China
  • Online:2017-04-25 Published:2017-12-18

Abstract:
Objective:To study the influence of minimally invasive embedded wire on serum IgE, IgG, IgA and PAF of children with cough variant asthma.
Methods:A total of 206 children with CVA who received treatment from Mar. 2013 to Dec.2015 were randomly divided into observation group(101 children) and control group(105 children). The observation group was treated with minimally invasive embedded wire and montelukast chewable tablets, while the control group only took montelukast chewable tablets. The treatment course was 3 months for both groups. Observe the clinical effect and the changes of IgE, IgG, IgA and PAF after treatment.
Results:The total effective rate of the observation group was 93.1%(94/101) and it was 87.6%(92/105) in the control group, the difference between them was of statistical significance(P<0.05).The improvement in serum level of total IgE,IgG,IgA and PAF was better in the observation group after treatment, and there was statistical difference(P<0.05).
Conclusion:Minimally invasive embedded wire can increase the level of IgA and IgG and the children's immunity.It can inhibit the excessive release of PAF and control inflammation level. It effectively reduce IgE-mediated allergic reaction and airway allergic inflammation.

Key words: Cough variant asthma, Minimally invasive embedded wire, Children