ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2017, Vol. 9 ›› Issue (2): 133-135.doi: 10.3969/j.issn.1674-3865.2017.02.013

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Effect of montmorillonite powder combined with bifid tiple viable on VIP, NPY and 5-HT of children with diarrhea

MA Huiling   

  1. Pediatric Department of the Second Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,China
  • Online:2017-04-25 Published:2017-12-18

Abstract:
Objective:To investigate the clinical effect of montmorillonite powder combined with bifid triple viable capsule in treating infantile diarrhea and its effect on vasoactive peptide(VIP), neuropeptide Y(NPY) and intestinal mucosa 5-hydroxytryptamine(5-HT).
Methods:A total of 124 child patients(under the age of three) diagnosed with diarrhea in our hospital from March 2014 to March 2016 were selected. They were randomly divided into groups: control group(62 cases) and observation group(62 cases). The children in control group were only given montmorillonite powder for oral treatment, while the children in observation group received bifid tiple viable treatment in addition to montmorillonite powder. Observations the remission situation of patients in the two groups and determine the level of VIP, NPY, intestinal mucosal 5-HT and serum CRP in the groups.
Results:The indexes of VIP, NPY, 5-HT and CRP in the observation group were significantly better than those before treatment, and the improvement was much greater than that of the control group. The children in observation group were better than those in control group in terms of diarrhea stopping time, fever abatement time and recovery of bowel movement. The above-mentioned differences all showed statistical significance(P<0.05).
Conclusion:The combined treatment of montmorillonite powder with bifid triple viable capsule has a significant effect on infantile diarrhea. It's worth promoting for it can quickly relieve clinical symptoms, improve the level of VIP, NPY and intestinal mucosa 5-HT and reduce inflammatory reaction.

Key words: Diarrha montmorillonite powder, Bifid tiple viable, Vasoactive peptide, vasoactive peptide Y, 5-Hydroxytryptamine, Children