Abstract:
Objective
To observe the effect of lung protective ventilation strategy on the treatment for children with acute respiratory distress syndrome.
Methods
From January 2014 to January 2016,80 cases of acute respiratory distress syndrome in Hunan Children's Hospital were randomly divided into the control group and the observation group,40 cases in each group. The control group received traditional mechanical ventilation strategy,and the observation group adopted the lung protective ventilation strategy,the other treatments being the same. The indicators were observed after treatment,including inspiratory peak pressure,positive end expiratory pressure,mean airway pressure,inhaled oxygen concentration,respiratory rate,arterial blood gas analysis,and complications.
Results
The peak inspiratory pressure,mean airway pressure and suction parameters of oxygen concentration in observation group were significantly lower than those in control group,while positive end expiratory pressure and frequency of respiration parameters were significantly higher,the difference being statistically significant(P<0.05). The pH and PaO2 of the observation group were significantly lower than those of the control group,and the PCO2 was significantly higher than that of the control group,the difference being statistically significant (P<0.05).The incidence rate of ventilator induced lung injury,intraventricular hemorrhage and patent ductus arteriosus had no statistical difference after treatment in observation group(P>0.05),while the incidence rate of adverse reactions was lower than that of control group,the difference being statistically significant(P<0.05).
Conclusion
In the treatment of children with acute respiratory distress syndrome,the lung protective ventilation strategy can optimize the ventilator parameters,improve the arterial blood gas value of children,and reduce the incidence of adverse reactions,which has important clinical value and application significance.

Key words: Acute respiratory distress syndrome, Lung protective ventilation strategy, Mechanical ventilation, Children