Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2018, Vol. 10 ›› Issue (4): 327-329.doi: 10.3969/j.issn.1674-3865.2018.04.016
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GAO Chuchu,YANG Zuming,WANG Sannan,CAI Yan
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Abstract: Objective To analyze the clinical characteristics and pathogenic bacteria distribution of early-onset and late-onset neonatal sepsis, in order to aid in the early clinical diagnosis and treatment. Methods From Jan. 2017 to Oct. 2017, 28 cases of early-onset neonatal sepsis and 31 cases of late-onset neonatal sepsis were treated in our hospital, and their clinical data were analyzed. Results The incidence of apnea, abdominal distention and heart rate increase was significantly higher in lateonset group (P<0.05). There was no statistical difference in the incidence of abnormal body temperature, milk decrease, jaundice, skin empyesis or shortness of breath. Percentage of elevated C-reactive protein in late-onset group was significantly higher than that in early-onset group (P<0.05). There was no statistical difference in the percentage of abnormal WBC or platelet decrease. Streptococcus agalactiae was detected with the highest frequency in early-onset group(25%,7/28), while klebsiella pneumonia was the most frequently detected strain in late-onset group(38.71%,12/31). Conclusion The symptoms of apnea, abdominal distention and heart rate increase are more common in late-onset neonatal sepsis than in early-onset neonatal sepsis. C-reactive protein is an important indicator in early evaluation of late-onset neonatal sepsis. Early-onset and late-onset neonatal sepsis differ in the distribution of pathogenic bacteria. Antibiotics should be used according to actual clinical conditions.
Key words: Neonatal sepsis, Early-onset sepsis, Late-onset sepsis, Pathogen, Infant, newborn
GAO Chuchu,YANG Zuming,WANG Sannan,CAI Yan. Clinical characteristics and etiology of early-onset and late-onset neonatal sepsis[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(4): 327-329.
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URL: https://www.zxek.net/EN/10.3969/j.issn.1674-3865.2018.04.016
https://www.zxek.net/EN/Y2018/V10/I4/327