Abstract: Objective
To explore the effectiveness of internal and external treatment by traditional Chinese treatment combined with western medicine for enuresis in children.
Methods
A total of 67 enuresis children(aged 7 to 17) with spleen and kidney Yang-insufficiency were chosen as the research subjects, who were treated in Beijing Children's Hospital from Nov. 2016 to Dec. 2017. They were divided into two groups according the random number table method: 35 in the western medicine treatment group and 32 in the integrated Chinese and western medicine treatment group. Both groups were treated with desmopressin(orally taken) according to the recommendations of International Pediatric Urinary Control Association and Chinese expert consensus on the management of children's single-symptom night enuresis disease. In addition, the integrated treatment group was treated with Chinese medicine(orally taken) assisted by acupuncture point paste. The treatment lasted for 4 weeks as one course. Observe the clinical effect, improvement in TCM syndromes and the adverse events during treatment in the two groups.
Results
Of the 63 children who were enrolled in the study and completed the treatment and follow-up, there were 32 in the western medicine treatment group and 31 patients in the integrated Chinese and western medicine group. The total effective rate was 90.3%(28/31) in the integrated Chinese and Western medicine group and 84.4%(27/32) in the western medicine treatment group. There was no significant difference in the effective rate between the two groups(P>0.05). The improvement rate of TCM syndromes in the integrated group was 96.8%(30/31), which was significantly better than that in the western medicine group(62.5%，20/32), and the difference was statistically significant(P<0.05). In the two groups, no significant drug-related adverse reactions were observed during the treatment.
ConclusionDesmopressin combined with TCM syndrome differentiation treatment（traditional Chinese medicine treatment combined with acupuncture point paste） has significant effect on the improvement of TCM syndromes of spleen and kidney Yang-insufficiency in children with enuresis, and can effectively improve the TCM symptoms and physique of children with enuresis.

Key words: Enuresis, Integrated Chinese and western medicine, Acupuncture point paste, Children