Abstract: Objective To observe the effect of atomization inhalation of ribavirin in the treatment of infantile herpangina and its effect on serum immunoglobulin level. Methods Totally 116 children diagnosed with herpangina from December 2017 to February 2019 in pediatrics department of our hospital were selected and divided into control group and observation group according to the random number table,with 58 cases each.Both groups were treated with conventional symptomatic therapy,and the observation group was treated with atomization inhalation of ribavirin on the basis of this,with a course of treatment of 5d in both groups.The therapeutic effect was observed and the serum immunoglobulin levels were compared and analyzed. Results The time of recovery of body temperature,disappearance of herpes and disappearance of sore throat in the observation group was shorter than that in the control group(P<0.05).The serum IgA,IgG and IgM in the observation group were increased and were higher than those in the control group(P<0.05).The total effective rate in the observation group was 9138%(53/58),which was higher than that in the control group(77.59%,45/58)(P<005). Conclusion The atomization inhalation of ribavirin can enhance the immune function of children with herpangina.The effect is good and it is worthy of clinical application.

Key words: Herpangina, Ribavirin, Atomization inhalation, Immunoglobulin, Children