Abstract: Objective To study the quality of life of children with epilepsy and what factors affect it.Methods Totally 75 children with epilepsy treated in the Department of Neurology and Department of Pediatrics of the People′s Hospital of Zhengzhou from January 2016 to January 2018 were randomly selected as the experimental group，At the same time normal children undergoing physical examination in the People′s Hospital of Zhengzhou were included as the control group.Quality of Life in Childhood Epilepsy(QOLCE) was used to assess the quality of life of children in the two groups.Their parents′ age,family income and parents′ education were recorded.At the same time,the age of onset,type of seizure,course of disease,type of medication and frequency of seizure in the recent half year were recorded.The difference in quality of life between the experimental group and the control group was compared,and the correlation between these factors and children′s quality of life was analyzed.Results The QOLCE score of the experimental group was lower than that of control group(P<0.05).There was no statistical difference between the parents of the two groups in age,educational background or family income(P>0.05).The QOLCE score of epileptic children had no significant correlation with their parents′ educational background,age of onset or family income,but was significantly negatively correlated with the frequency of seizures,the type of antiepileptic drugs taken and the course of epilepsy,and was correlated with the type of seizures.Conclusion In order to improve the quality of life of children with epilepsy,we need to reduce the types of antiepileptic drugs clinically used,reduce the frequency of seizures,control seizures,and enhance the understanding of epilepsy in the children with epilepsy and their parents.

Key words: Epilepsy, Quality of life, Children