Abstract: Objective: To explore and analyze the clinical features and auxiliary examination results of children with pertussis.Methods: A total of 100 children with pertussis treated in our hospital from September2018 to January 2020 were chosen as research subjects, and the clinical characteristics were analyzed by descriptive method based on the information of symptoms, signs, baseline data, auxiliary examination and so on.Results: Totally 77 children were positive by PCR and 34 were positive by PT-IgG; including 6 cases of negative PCR and 17 without detection. There were 62 children under 6 months. Among the 100 children, there was statistical difference in no-vaccination between the common pertussis children and severe pertussis children（P<0.05）. There was statistical differences in spasticity, cyanosis around mouth and apnea betweencommon pertussis children and severe ones when coughing（P<0.05）,while there was no statistical difference in red face,cockcrow echo or short of breath between them(P>0.05). Auxiliary examinations showed that there was no statistical difference in the complication with choamydiae infection/pneumonia, respiratory virus infection or EB virus infection between common pertussis children and severe ones（P>0.05）. There was statistical difference in normal WBC count, WBC count>30×109/L and hypoxia betweencommon pertussis children and severe ones（P<0.05）, and there was also statistical difference in the increase in WBC count, WBC count being (15-30)×109/L,the increase in lymphocyte proportion, the increasein C-reactive protein, the increase in hypersensitive C-reactive protein, the increase in procalcitonin, the increase in transaminase, the increase in myocardial enzymes, chest imaging pneumonia,emphysema, respiratory failure and atelectasis between them（P<0.05）.There was one case of death after being transferred to another hospital, and the other childrenhad one to five months of cough after discharge.Conclusion: The children with pertussis are mostly under 6 months of age, and the disease is more likely to occur in children who are not vaccinated. The main source of infection is family members, and the clinical manifestations of spastic cough are often seen. The prognosis is quite good.

Key words: Pertussis, Auxiliary examination, Clinical features, Vaccination