Abstract: Objective  To screen and evaluate the opinions of pediatricians of integrated traditional Chinese and Western medicine on the diagnosis and treatment of precocious puberty, providing basis for formulating the integrated traditional Chinese and Western medicine guildline for diagnosis and treatment of child precocious puberty. Methods The Delphi questionnaire was used to investigate the diagnosis and treatment of children's precocious puberty based on integrated traditional Chinese and western medicine among 52 pediatric experts of integrated traditional Chinese and Western medicine in China, the results were statistically analyzed, and the indicators of the integrated traditional Chinese and western medicine guildline for diagnosis and treatment of children's precocious puberty were formulated.Results Totally 52 and 51 questionnaires were received in the first and second rounds of survey respectively, and the positive indexes of experts were 100% and 98.09%, respectively. The  of all items in the two rounds of questionnaires ranged from 0.33 to 2.00, Sum ranged from 28 to 104, R ranged from 0% to 69%, and CV ranged from 0% to 160%.Conclusion Enthusiasm and professional level of the experts in this survey are high and the geographical coverage is wide. The expert questionnaire survey based on Delphi method can well summarize the plan for diagnosis and treatment by integrated traditional Chinese and western medicine for precocious puberty, and provide objective basis for formulating the draft of the guildline.

Key words:

Precocious puberty, Delphi method, Integrated traditional Chinese and western medicine