ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2023, Vol. 15 ›› Issue (4): 314-318.doi: 10.3969/j.issn.1674-3865.2023.04.008

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Research progress in the genetics of febrile seizures in children

JIANG Yanli, YAN Lulu, XIE Min, ZHUANG Danyan, LI Haibo   

  1. School of Medicine,Ningbo University,Ningbo 315000,China

  • Received:2023-03-23 Published:2023-08-25 Online:2023-08-25
  • Contact: LI Haibo,E-mail:lihaibo-775@163.com

Abstract: Febrile seizures(FS) is one of the most common diseases in infancy and early childhood, and some children with FS progress to epilepsy in the later stage of the disease. At present, the pathogenesis of FS is not clear. In recent years, studies have shown that FS has a significant familial genetic tendency, and their pathogenesis is related to mutations in sodium channel genes, potassium channel genes, chloride channel genes, cytokine genes, proline-rich transmembrane protein 2 gene, and synaptic fusion protein 1B gene. 

Key words: Febrile seizures, Genetics, Gene, Epilepsy