ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2023, Vol. 15 ›› Issue (3): 199-202.doi: 10.3969/j.issn.1674-3865.2023.03.004

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Application of metagenomic next generation sequencing in the diagnosis of respiratory infectious diseases in children

LAI Dingxiang, ZHENG Jishan, PAN Yun, ZHOU Ying, LI Haibo   

  1. School of Medicine,Ningbo University,Ningbo 315000,China
  • Received:2023-03-02 Published:2023-06-25 Online:2023-06-25
  • Contact: ZHENG Jishan,E-mail:zjs222@163.com;LI Haibo,E-mail:lihaibo-775@163.com

Abstract: Respiratory tract infection is the most common infection in children,which seriously threatens the life and health of children.Early identification of pathogens is of great significance for the clinical diagnosis and treatment of such diseases.Metagenomic next generation sequencing(mNGS) has the advantages of unbiasedness,full coverage and high efficiency,and is now being applied to clinical diagnosis of infectious diseases.This article introduces the application value of mNGS in children′s respiratory infectious diseases through a series of examples.

Key words:

Respiratory infection, Metagenomic next generation sequencing, Application, Children