Abstract: Objective To observe the clinical effect of Jianer Zhuzhang paste in the treatment of spleen and kidney deficiency in short stature children.Methods A total of 120 short stature children with spleen and kidney deficiency were selected， who were admitted to the Department of Pediatrics of Zhejiang Provincial Hospital of Traditional Chinese Medicine from March to May in 2020 and 2021， and they were divided into a treatment group and a control group by random number table method, with 60 cases in each group. Each group was divided into two subgroups according to age: 3-6 years old（n=30） and 7-11 years old（n=30）. Both groups were given lifestyle intervention for 6 months, and the treatment group was additionally treated with Jianer Zhuzhang paste for 2 months. After 2 months and 6 months, the clinical efficacy, height increase, bone age change and adverse reactions of the two groups were counted.Results In the children aged 3 to 6 years，the total effective rate of the treatment group was 73.33%(22/30),higher than that of the control group(26.67%,8/30)(P<0.05). The height increase of the treatment group in 2 months and 6 months was greater than that of the control group (P<0.05). In the children aged 7 to 11 years, the total effective rate was 63.33%（19/30）, which was higher than that of the control group(20.00%,6/30) (P<0.05).The height increase had no statistical difference between the two groups after two months of treatment(P>0.05).The height increase in treatment group was greater than that in control group at 6 months of treatment, with statistical difference(P<0.05). There was no difference in bone age change between the two groups at 6 months of treatment(P>0.05).Conclusion Jianer Zhuzhang paste can effectively improve the growth rate of children, has no adverse effect on bone age, and has good compliance in children and parents, which is worthy of clinical application.

Key words:

Short stature children, Deficiency of spleen and kidney, Acupoint application, External treatment