Objective：To explore the effect of botulinum toxin A combined with plaster cast on the gross motor function of spasmodic double paralysis.

Methods：A total of 40 children with spasmodic double paralysis hospitalized in Xiamen Maternal and Child Healthcare Hospital from Jan. 2013 to Oct. 2014 were included in the study, and they were randomly divided into two groups:observation group(20 cases) and control group(20 cases). Control group was treated only with botulinum toxin A injection followed by rehabilitation training. Observation group was given with botulinum toxin A combined with 3 weeks of plaster cast, and then rehabilitation training was carried out after removing the plaster. GMFM-88 was used to make evaluation of zone D and zone E before treatment and 1,3 and 6 months after treatment.

Results：Zone D and E was different 1,3 and 6 months after treatment by GMFM-88 in the observation group, compared with that before treatment, the difference being statistical(P<0.01). Zone D and E showed statistical difference 3 and 6 months after treatment in the control group compared with before treatment(P<0.01). Zone D and E showed statistical difference between observation and control group 1,3 and 6 months after treatment(P<0.01).
Conclusion：Botulinum toxin A injection combined with plaster cast is effective in treating pointed foot deformity of spasmodic double paralysis, and it can reduce muscle tone, improve motion function and effectively improve gross motion function, which is better than single use of botulinum toxin A.