Abstract: Objective：To observe the clinical efficacy of modified asthma tonifying ointment combined with Sanfu plaster in the treatment of children with asthma in remission stage.
Methods：A total of 70 children with asthma in remission stage treated from August 2017 to June 2018 in Sichuan Hospital of Traditional Chinese Medicine were selected and randomly divided into control group(n=34) and observation group(n=36).The control group was treated with inhaled budesonide suspension and oral montelukast sodium chewable tablets,while the observation group was treated with oral asthma tonifying ointment with modification and Sanfu plaster.The course of treatment was 3 months.After treatment,the clinical effects of the two schemes were compared in terms of control level of asthma symptoms,lung function,TCM symptom score,TCM syndrome efficacy and safety.
Results：After treatment,there were 6 cases lost in observation group and 4 in control group.There was no significant difference in the control level of asthma symptoms or the time of nonwheezing symptoms between the two groups(P>0.05).In terms of pulmonary function,the PEF values of the two groups after treatment were lower than those before treatment,and the difference was statistically significant(P<0.05);there was no significant difference in PEF value between the two groups after treatment（P>0.05）.After treatment,the total score of TCM symptoms in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the TCM symptom scores of repeated colds,spontaneous sweating,poor appetite and abnormal stool in the observation group were significantly lower than those in the control group(P<0.05).The total effective rate in the observation group was 96.7%(29/30),which was significantly higher than that in the control group(43.3%,13/30),and the difference was statistically significant(P<0.05).There was no obvious adverse reaction during and after treatment with asthma tonifying ointment combined with Sanfu plaster for lung and spleen qi deficiency syndrome in children with asthma in remission stage.
Conclusion：Modified asthma tonifying ointment combined with Sanfu plaster is effective and safe in the treatment of children with asthma in remission stage.

Key words: Asthma in remission stage, Lung-spleen qi deficiency, Clinical efficacy, Safety