Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2021, Vol. 13 ›› Issue (5): 416-420.
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Objective:To investigate the clinical characteristics and treatment of 23 hospitalized children with pertussis in Chengdu.#br# Methods:The clinical data of 23 children with pertussis receiving treatment from January 2018 to December 2019 were retrospectively analyzed.#br# Results:The characteristics of 23 hospitalized children were as follows:(1)Age: there were 15 babies, 5 infants and 3 preschool children.(2)Vaccination history: 3 had none,8 cases had 1 or 2 doses, and 12 had 3 or 4 doses.(3)Respiratory infection history in the family: 19 cases had clear contact history with respiratory symptoms.(4)Season of disease: there were 7 cases(30.4%) in spring,4 in summer(17.4%), 4 in autumn(17.4%) and 8 in winter(34.8%).(5)Laboratory examination: Blood routine examination: Twenty children had WBC≥15×10.9/L, the median value being 21.46×10.9/L; being complicated with other pathogens: 5 cases were infected by the bacteria and 5 cases with respiratory syncytial virus. Chest radiographs showed pulmonary infection in 7 cases.#br# Conclusion:Winter and spring are the high incidence season of pertussis in Chengdu. Infants, the children with a history of contacting with people with respiratory infection and those being not fully vaccinated and being not revaccinated against pertussis in time are at high risk of pertussis.At the same time, hyperleukaemia, pulmonary infection and organ function impairment are the high risk factors for severe pertussis.