Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2021, Vol. 13 ›› Issue (5): 431-435.
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Objective:To summarize and analyze the rules of medication and prescriptions of Traditional Chinese Medicine(TCM) experts in treating children with cough.#br# Methods:The child cases of cough treated by chief physician Wang Yonghong between April 2019 and October 2019 were collected and entered into TCM Inheritance Support System(V2.5).The association rules, entropy clustering of complex systems,unsupervised entropy hierarchical clustering and other data mining methods were used to count the frequency of the herbs in chief physician Wang's prescriptions for cough. Analyze the association rules between commonly used herbs,and excavate prescription herbs combinations and potential core prescriptions. #br# Results:Among the 301 collected prescriptions for children's cough,the four most frequently used herbs were Huangqin(Radix Scutellariae Baicalensis),Xingren(Semen Armeniacae Amarum),Chenpi(Citrusreticulata Blanco),Zhibanxia(prepared Rhizoma Pinelliae);the core prescription for children's cough was extracted by the association rule analysis ,which contained these following herbs:Huangqin(Radix Scutellariae Baicalensis),Xingren(Semen Armeniacae Amarum),Chenpi(Citrusreticulata Blanco),Zhibanxia(prepared Rhizoma Pinelliae),Chantui(Periostracum Cicadae),Kuandonghua(Flos Farfarae),Fuling(Poria),Sangbaipi(Morus albaL),Chaobaizhu(roasted Rhizoma Atractylodis Macrocephalae);8 groups of core herb combination and 4 potential prescriptions for cough were obtained by using the entropy clustering analysis method.#br# Conclusion:The cough in children is most likely caused by "diseased lung and spleen,exogenous evil attacking lung", so we should follow the principle of "simultaneous treatment of lung and spleen" during treatment. The combination of Dingchuan decoction,Zhisou powder and Erchen decoction should be used with modification to treat cough in children.