Abstract: A boy, aged 26 months, had hypophosphoric rickets with abnormal blood coagulation and liver function. The clinical manifestations were unsteady walking, epistaxis, nausea and vomiting. Through the analysis of the etiology of hypophosphoric rickets and the in-depth auxiliary examination, the child was finally diagnosed with type 1 tyrosinemia. Thus, we reanalyzed the diagnosis and treatment process of hypophosphoric rickets in children.

Key words: Rickets, Hypophosphoric rickets, Fanconi syndrome, Type 1 tyrosinemia