Abstract: Objective To investigate the efficacy of low temperature plasma adenoidectomy with that of electric aspiration adenoidectomy in the treatment of secretory otitis media in children with adenoid hypertrophy.Methods From January 2021 to May 2022，70 children with secretory otitis media complicating adenoid hypertrophy were enrolled in our hospital.The randomized number table method was used to randomly divide them into two groups,with 35 in each. Group A(control group) received electric aspiration adenoidectomy + catheterization，while group B(observation group) received low temperature plasma adenoidectomy + catheterization）.Observe the treatment effect，hearing intensity before and after surgery，operation time，postoperative pain score,intra-operative bloodloss,incidence of adverse events and expression of serum inflammatory factors were observed. Results After treatment，the effective rate of group A was 71.4%，which was significantly lower than that of group B(97.1%) and the difference was statistically significant（P＜0.05）.The air conduction level and the bone conduction were significantly lower in the two groups after treatment，but the difference between the two groups was not statistically significant（P＞0.05）.The operation time，the pain score at 12h after operation and the intraoperative blood loss were significantly lower in group B than in group A，the difference being statistically significant（P＜0.05）.The incidence of adverse events in group A was 28.6%(10/35), significantly higher than that in group B(5.7%,2/35),and the difference was statistically significant（P＜0.05）.Serum IL-1β and TNF-α were significantly lower in group B than in group A at 1 month and 6 months after treatment（P＜0.05）. Conclusion Low-temperature plasma adenoidectomy combined with catheterization,compared with electric aspiration adenoidectomy, has a better effect，reducing the operation time，intraoperative blood loss and postoperative 12h pain score.The incidence of adverse events and the levels of serum IL-1β and TNF-α at 1 month and 6 months after treatment are reduced，but it has no particular effect on hearing improvement.

Key words:

Secretory otitis media；Low temperature plasma adenoidectomy, Electric aspiration adenoidectomy, Adenoid hypertrophy being prolonged unhealed, Catheterization, Children