Abstract: Objective：To evaluate the clinical efficacy of Yipi Xiaoshi decoction in the treatment of children with indigestion with spleen deficiency and accumulation syndrome.Methods：Totally 60 children with indigestion (with spleen deficiency and accumulation syndrome) admitted to Dongying Traditional Chinese Medicine Hospital from March 2023 to March 2024 were selected as the study subjects,and they were randomly divided into an observation group and a control group,with 30 cases in each group.The control group was given Xingpi Yanger granules orally,while the observation group was given Yipi Xiaoshi decoction orally.After two treatment courses (14 days),the major symptoms (lack of appetite,reduced food intake,and bloating in the epigastric region) and minor symptoms (nausea and vomiting,fatigue,pale complexion,and irregular bowel movements) were quantitatively scored and the efficacy was evaluated.Results：(1) The total effective rate of both groups was 100%,with a significant improvement rate of 93%-3%(28/30) in the observation group,which was significantly higher than that of the control group (26%-7%,8/30),and the difference was statistically significant(P<0.05).(2) After treatment,the scores of each major and minor symptom,as well as the total score of symptoms in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).Conclusion：Yibi Xiaoshi decoction has a definite therapeutic effect on children with indigestion with spleen deficiency and accumulation syndrome,which improves the score of traditional Chinese medicine syndrome,and is worthy of clinical promotion and application.

Key words: Indigestion, Type of spleen deficiency and accumulation syndrome, Yipi Xiaoshi decoction, Child