ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (6): 527-.

• 临床研究 • 上一篇    下一篇

腹型过敏性紫癜患儿临床特征分析及窄带成像技术下内镜诊断的应用价值

李九英，李平真，邱亚明   

  1. 475000 河南 开封，开封市儿童医院消化内科(李九英,李平真);475000 河南 开封，河南大学淮河医院儿科(邱亚明)
  • 出版日期:2020-12-25 发布日期:2021-05-14
  • 通讯作者: 李九英，E-mail：chezhan6969@163.com
  • 作者简介:李九英（1976-），女，医学硕士，副主任医师。研究方向：小儿内科疾病的诊治

Clinical characteristics of children with Henoch-Sehonlein purpura of abdominal type and the application value of endoscopic diagnosis under narrow band imaging

LI Jiuying,LI Pingzhen,QIU Yaming   

  1. Department of Gastroenterology,Kaifeng Children's Hospital，Kaifeng 475000，China
  • Online:2020-12-25 Published:2021-05-14

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摘要： 目的:分析腹型过敏性紫癜（HSP）患儿的临床特点以及窄带成像技术（NBI）内镜对腹型HSP的诊疗应用价值。
方法:选择本院2016年5月至2019年5月收治的疑似腹型HSP患儿70例，分别给予腹部B超及NBI内镜检查，总结HSP患儿的临床特点。以病理诊断结果为标准，比较两种检查方法对腹型HSP的诊断率，分析NBI内镜在腹型HSP患儿临床诊断中的应用价值。
结果:本研究70例腹型HSP患儿均有不同程度的腹痛，有或无阵发性加重，疼痛部位不固定，以脐周为主，所有患儿病程中均出现皮肤紫癜症状；NBI内镜对腹型HSP检查的灵敏度、特异度、准确率分别为95.24%（60/63）、71.43%（5/7）、92.86%（65/70），与腹部B超检查的79.25%（42/53）、29.41%（5/17）、67.14%（47/70）相比，在灵敏度和准确率方面比较差异有统计学意义（P<0.05）。
结论:腹型HSP患儿的胃肠道症状无明显特异性，NBI内镜检查对小儿腹型HSP的灵敏度及准确率较高，可为小儿HSP的临床诊疗提供可靠的依据，具有较高的临床应用价值。

关键词: 腹型过敏性紫癜, 临床特征, 内镜检查, 窄带成像技术, 应用价值

Abstract: Objective:To analyze the clinical characteristics of children with Henoch-Sehonlein purpura(HSP) of abdominal type and the application value of NBI endoscopy in the diagnosis and treatment of HSP of abdominal type.
Methods:Seventy children with suspected HSP of abdominal type who were admitted to the hospital between May 2016 and May 2019 were selected as the subjects. They were examined with abdominal B ultrasound and NBI endoscopy. The clinical characteristics of children with HSP were summarized. Based on the pathological diagnosis results, the diagnosis rates of HSP of abdominal type by the two examination methods were compared. The application value of NBI endoscopy in the clinical diagnosis of children with HSP of abdominal type was analyzed.
Results:In this study, all subjects had different degrees of abdominal pain, with or without paroxysmal exacerbation. The pain was not fixed, but was mainly around the navel, and all children had symptoms of skin purpura in the course of the disease. The diagnostic sensitivity, specificity and accuracy of NBI endoscopy for HSP of abdominal type were 95.24%(60/63), 71.43%(5/7) and 92.86%(65/70), respectively. Compared with 79.25%(42/53), 29.41%(5/17) and 67.14%(47/70) by abdominal B ultrasound examination, the differences in sensitivity and accuracy were significant (P<0.05).
Conclusion:There are no specific gastrointestinal symptoms in children with HSP of abdominal type. The diagnostic sensitivity and accuracy of NBI endoscopy in children with HSP of abdominal type are high, which can provide a reliable basis for the clinical diagnosis and treatment of children with HSP and the clinical application value is high.

Key words: Henoch-Sehonlein purpura of abdominal type, Clinical characteristics, Endoscopy, Narrow band imaging, Application value