ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2025, Vol. 17 ›› Issue (4): 281-286.doi: 10.20274/j.cnki.issn.2025.04.002

• 儿童抽动障碍康复专栏 • 上一篇    下一篇

基于数据挖掘分析现代名中医治疗抽动障碍的用药规律

孙远航1, 李冬梅2()   

  1. 110847 沈阳,辽宁中医药大学2022级中医儿科学专业研究生(孙远航)
    110032 沈阳,辽宁中医药大学附属医院儿科(李冬梅)
  • 收稿日期:2025-03-09 修回日期:2025-05-08 出版日期:2025-08-25 上线日期:2025-08-25
  • 通讯作者: 李冬梅 E-mail:amei888@126.com
  • 作者简介:孙远航(1999-),男,辽宁中医药大学2022级硕士研究生。研究方向:中医药治疗小儿神经系统疾病
  • 基金资助:
    国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函〔2022〕1号);辽宁省教育厅高等学校基本科研项目(面上项目)(LJKZ0890)

Data mining-based analysis of medication patterns of modern renowned traditional Chinese medicine physicians for tic disorders

Yuanhang SUN1, Dongmei LI2()   

  1. 1.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China
    2.Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,China
  • Received:2025-03-09 Revised:2025-05-08 Published:2025-08-25 Online:2025-08-25
  • Contact: Dongmei LI E-mail:amei888@126.com
  • Supported by:
    Basic Scientific Research Project of Colleges and Universities of the Education Department of Liaoning Province (General Program)(LJKZ0890)

摘要:

目的 借助中医传承计算平台(V3.5)软件,揭示现代名中医治疗抽动障碍的共性辨证思路及核心方药配伍策略。 方法 收集中国知网(CNKI)、万方数据知识服务平台、维普中文科技期刊数据库2000年1月至2025年2月有关名中医治疗抽动障碍的文献为研究资料,通过中医传承计算平台(V3.5),录入抽动障碍治疗处方,对药物频次,关联规则、聚类分析,性味归经、功效等进行统计分析。 结果 共收集到符合纳入排除标准的文献78篇,涉及61位名中医的用药经验,收集相关处方104条,包含214种药物。性味归经规律:药性以寒、平为主,五味以甘、苦居多,归经集中于肝、肺、脾。核心组合以“白芍-钩藤-甘草”为角药,辅以天麻、僵蚕、蝉蜕、石菖蒲、茯苓、菊花、牡蛎、全蝎、柴胡为核心处方。 结论 现代名中医在治疗抽动障碍时,以柔肝息风为主要治则,兼以平肝泻火、健脾化痰、宣肺透邪等治法,注重辨证论治,标本同治,用药以平肝息风类、补虚类、解表类为主。

关键词: 抽动障碍, 名中医, 数据挖掘, 中医传承计算平台(V3.5), 儿童

Abstract:

Objective To elucidate the common syndrome differentiation approaches and core prescription strategies of modern renowned traditional Chinese medicine (TCM) physicians in treating tic disorders using the TCM Inheritance Computing Platform(V3.5). Methods Literature on renowned TCM physicians' treatment for tic disorders was collected from the China National Knowledge Infrastructure (CNKI), Wanfang Data Knowledge Service Platform, and VIP Chinese Sci-Tech Journal Database from January 2000 to February 2025. Prescriptions for tic disorders were input into the TCM Inheritance Computing Platform(V3.5) for statistical analysis of frequency of medicinal use, association rules, cluster analysis, channel tropism of property and flavor, and efficacy. Results A total of 78 articles which met the inclusion criteria were collected, involving the experience of 61 renowned TCM physicians, and 104 prescriptions comprising 214 medicinal substances were included. Medicinal properties were predominantly cold and neutral; flavors were primarily sweet and bitter; channel tropism focused on the liver, lung, and spleen. The core combination was Baishao (Paeoniae Radix Alba), Gouteng (Uncariae Ramulus cum Uncis), and Gancao (Glycyrrhizae Radix et Rhizoma), supplemented by the core prescription of Tianma (Gastrodiae Rhizoma), Jiangcan (Bombyx Batryticatus), Chantui (Cicadae Periostracum), Shichangpu (Acori Tatarinowii Rhizoma), Fuling (Poria), Juhua (Chrysanthemi Flos), Muli (Ostreae Concha), Quanxie (Scorpio), and Chaihu (Bupleuri Radix). Conclusion The primary treatment principle of modern renowned TCM physicians for tic disorders is softening the liver and extinguishing wind, complemented by strategies such as calming the liver and purging fire, fortifying the spleen and resolving phlegm, and diffusing the lung and dispelling pathogens. Attention should be paid to syndrome differentiation and simultaneous treatment of root causes and symptoms, and the medicines used mainly include liver-calming and wind-extinguishing agents, tonics, and exterior-releasing substances.

Key words: Tic disorder, Renowned TCM physicians, Data mining, TCM Inheritance Computing Platform(V3.5)

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