Abstract:
Objective：To observe the clinical effects of azithromycin sequential therapy for children with mycoplasma pneumonia.
Methods：Totally 96 children with mycoplasma pneumonia who received treatments in Fuyong People's Hospital from June 2013 to August 2014 were taken as the research subjects，and these patients were randomly divided into the control group and the observation group，with 48 patients in each group.In the control group，they were treated with the erythromycin sequential therapy:erythromycin injection was administered intravenously once a day，continuously for 5 days，and then they were treated with the erythromycin tablets orally，3 times a day，continuously for 7 days;in the observation group，they were treated with the azithromycin sequential therapy，azithromycin injection for intravenous drip，once a day，and 5 days later the treatment was stopped for 4 days，and then azithromycin dry suspension was given orally，once a day，continuously for 3 days.Then，the treatment effect and adverse reaction of the two groups were observed.
Results：The total effective rate in observation group was 97.9%(47/48)，which was higher than that in the control group ［85.4%(41/48)］，and the difference was statistically significant(P＜0.05).The incidence rate of adverse reactions in the observation group was 14.6%(7/48)，which was lower than that in the control group ［27.1%(13/48)］，and the difference was statistically significant(P＜0.05).
Conclusion：In the treatment of children with mycoplasma pneumonia，the azithromycin sequential therapy can significantly improve the clinical symptoms，and it has quick effect and fewer adverse reactions with other advantages;it is safe with significant effect and it can greatly reduce the pain and improve the quality of life of children，thus it should be promoted in the clinical application.

Key words: Pneumonia, mycoplasma, Erythromycin, Azithromycin, Sequential therapy, Clinical effect, Children