Abstract:
objective
To observe the clinical effect of Yupingfeng powder combined with fluticasone propionate aerosol for cough variant asthma of pulmonosplenic-qi deficiency type in children.
Methods
From April 2016 to February 2017, 90 cases of CVA children admitted to Baiyun District Hospital of Traditional Chinese Medicine and Huadu District Maternal and Child Health Hospital in Guangzhou were selected as the research subjects, and they were randomly divided into two groups:45 cases in the observation group and 45 in the control group. Three cases fell off in the observation group, with 42 cases included in the end; in the control group 5 cases fell off and finally 40 cases were included. The observation group was given oral Yupingfeng powder combined with fluticasone propionate aerosol and the control group was given fluticasone propionate aerosol. The two groups were treated for 12 weeks. The clinical efficacy, cough relief and disappearance time and adverse reactions of the two groups were observed. Four weeks after completion of treatment，the clinical effects of the two groups were compared by follow-up.
Results
After treatment, the total effective rate of the observation group(92.86%,39/42) was higher than that of the control group(77.50%,31/40), and the difference was statistically significant(P<0.05). The cough relief and disappearance time in the observation group was significantly shorter than that in the control group, and the difference was statistically significant(P<0.05). Four weeks after completion of treatment，the total effective rate of observation group(88.10%,37/42) was still higher than that of the control group(65%,26/40), and the difference was statistically significant(P<0.05), but the difference was not statistically significant(P>0.05) compared with that at the end of treatment. No obvious adverse reactions occurred during the treatment.
Conclusion
Yupingfeng powder granules combined with fluticasone propionate aerosols are superior to fluticasone alone in improving the symptoms of children with CVA of pulmonosplenic-qi deficiency type.

Key words: Cough variant asthma, Yupingfeng powder, Fluticasone propionate aerosol, Pulmonosplenic-qi deficiency type, Children