ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2022, Vol. 14 ›› Issue (5): 428-431.doi: 10.3969/j.issn.1674-3865.2022.05.011

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Mechanism of the effect of Yishen Tongdu acupuncture therapy on motor function, cognitive level and serum neurofactor level in children with spastic cerebral palsy

TAN Longze, LUO Wei, WANG Paoqiu, LIU Chunlei, HUANG Chao   

  1. Rehabilitation Center, Hunan Children's Hospital, Changsha 410007, China

  • Received:2022-03-17 Published:2022-10-25 Online:2022-10-25
  • Contact: LUO Wei,E-mail:ruby1013@163.com

Abstract: Objective To explore the application effect of Yishen Tongdu acupuncture therapy in children with spastic cerebral palsy(CP), and its influence on motor function, cognitive level and serum neurofactor level. Methods A total of 89 children with spastic cerebral palsy admitted to our department from August 2019 to September 2021 were selected as the research subjects and randomly divided into two groups. The control group(n=44) was given exercise therapy, and the observation group(n=45) was given exercise combined Yishen Tongdu acupuncture therapy. The motor function, cognitive function and neurofactor levels of the two groups were compared.  Results After treatment, the gross motor function and fine motor function scores of the observation group were higher than those of the control group (P<0.05). Gesell Developmental Diagnostic Scale scores of fine motor and language,and personal-social scores of observation group were higher than those of the control group(P<0.05), and the scores of gross motor and adaptability tended to increase, and the differences were not statistically significant(P>0.05). The levels of nerve growth factor and brain-derived neurotrophic factor in the observation group were higher than those in the control group(P<0.05).Conclusion Yishen Tongdu acupuncture combined with exercise therapy can effectively improve gross and fine motor function and promote neurocognitive development by strengthening kidney and spleen, Tongdu and dredging meridian, and regulating the expression levels of serum nerve growth factor and brain-derived neurotrophic factor.


Key words: Cerebral palsy, Spasm type, Yishen Tongdu acupuncture therapy, Cognitive function, Neurofactor