Abstract:
Objective: To observe the characteristics of blood glucose，insulin, cortisol and complication in neonates of mothers with gestational diabetes mellitus(GDM) and healthy macrosomia.
Methods: The 38 cases of neonates of GDM mothers(group A), 34 cases of healthy macrosomia of mothers without GDM(group B) and 35 healthy neonates of mothers without GDM(group C) born in our hospital from January 2014 to June 2015 were included in the study. The level of blood glucose，insulin and cortisol were measured in the three groups, and complication were also recorded in the 3 groups, including asphyxia, hypoglycemia, hyperbilirubinemia, hypocalcemia and polycythemia.
Results: Compared with group C，the level of blood glucose in group A and group B was apparently lower(P＜0.05), while the level of insulin and cortisol in group A and group B was apparently higher, the difference was of statistical significance. There was no difference in blood glucose, insulin or cortisol between group A and group B(P>0.05)| The incidence of hypoglycemia in group A was significantly higher than that in group C and the difference was statistical(P<0.017).
Conclusion: The abnormal rate of blood glucose，insulin and cortisol in the infants of gestational diabetic mothers and healthy macrosomia is high, and GDM neonates should be monitored for hypoglycemia.

Key words: Gestational diabetes mellitus, Blood glucose, Complication, Infant,newborn