Abstract:
ObjectiveTo explore mechanism of prevention and treatment of  Double Relieving Superficies Syndrome Methods by investigating the expression of TLR4MyD88NFκB P65 protein on influenza viral  pneumonia in mice.
MethodsThe mice were infected with influenza virus. The traditional Chinese medicine groups were provided for Yinqiao power，Yupingfeng power and Yinqiao power+Yupingfeng power. The control group was provided for ribavirin.Then expression of TLR4MyD88NFκB P65 protein was measured by SABC immunohistochemical assay after five days.
ResultsThe protein expression of TLR4MyD88NFκB P65 in Double Relieving Superficies Syndrome Methods group was lower than that of other groups(P＜0.05).
ConclusionInfluenza virus can trigger the TLR4MyD88NFκB P65 message channel. Double Relieving Superficies Syndrome Methods can suppress the expression of TLR4MyD88NFκB P65 protein and is better than others.

Key words: Double Relieving Superficies Syndrome Methods；TLR4MyD88NFκB P65;mice;animal, experiment