Abstract:
Objective
To investigate the treatment result of Suhuang cough-relieving capsule and its effect on immunologic function of children with cough variant asthma.
Methods
Eighty children with cough variant asthma admitted to Department of Pediatrics, the Second Hospital of Chaoyang from January 2015 to April 2016 were included, and equally randomized into treatment group and control group(n=40 per group). Children in the control group received routine treatment, and if necessary, inhalation therapy was given. In addition to the treatment for control group, the treatment group also received treatment of oral Suhuang cough-relieving capsule, 3 months as a course of treatment. After 3-month treatment, the total effect was observed, and serum CD4+, CD8+ levels of T lymphocyte subsets were measured by alkaline phosphatase-anti-alkaline phosphatase assay (APAAP method), and the ratio of CD4+/CD8+ was calculated.
Results
The total effective rate in the treatment group was significantly higher than that in the control group ［95% (38/40) vs. 80% (32/40), P<0.05］. Serum levels of CD4+ and CD8+ and their ratio were similar between the two groups before treatment(P>0.05). After treatment, serum level of CD4+ and the ratio of CD4+/CD8+ of both groups were significantly increased; however, serum level of CD8+ was decreased after treatment compared with before treatment (P<0.05).
Conclusion
Suhuang cough-relieving capsule can improve immunologic function and therapeutic effects in children with cough variant asthma.

Key words: Cough variant asthma, Suhuang cough-relieving capsule, Immunologic function, Child