ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2019, Vol. 11 ›› Issue (6): 461-464.doi: 10.3969/j.issn.1674-3865.2019.06.001

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Research on the medication rule of famous veteran doctor of TCM-Zhao Kun-in prescriptions containing Aconiti lateralis radix praeparata based on data mining

WANG Yanhui, SONG Guihua, ZHAO Kun   

  1. WANG Yanhui, SONG Guihua, ZHAO Kun. Henan Uni-versity of Traditional Chinese Medicine, Zhengzhou 450009,China

  • Received:2019-09-11 Published:2019-12-25 Online:2019-12-25
  • Contact: SONG Guihua, E-mail:songgh123@126.com

Abstract:

Objective:To explore the medication rule of famous veteran doctor of TCM-Zhao Kun-in prescription containing Aconiti lateralis radix praeparata.Methods:Based on the establishment of prescription database, the method of association rules was used to analyze the following items in the prescriptions containing Aconiti laterlis radix praeparata, including the frequency of single drug, frequency of drug combination, the association rules and the core drug combinations.Results:The prescriptions containing Aconiti lateralis radix praeparata were commonly used for treating asthma, cough and common cold. The drugs with highest frequency were Aconiti lateralis radix praeparata, Ephedrae herba, Farfarae flos, Houttuynia cordata thunb, Armeniacae semen amarum, Phragmitis rhizoma, Gypsum fibrosum and so on. The drug combinations with highest frequency were 'Aconiti lateralis radix praeparata and Ephedrae herba', 'Aconiti lateralis radix praeparata and Paeoniae radix rubra', and 'Aconiti lateralis radix praeparata and Pseudostellariae radix'. The drug association rules with the confidence being more than 0.9 were 'Aconiti lateralis radix praeparataEphedrae herba','Aconiti lateralis radix praeparataFarfarae flos', 'Paeoniae radix rubraAconiti lateralis radix praeparata', and'Paeoniae radix albaEphedrae herba, Aconiti lateralis radix praeparata', and so on. The core drug combinations of association rules for treating asthma, cough and common cold had some similarities to Mahuang Fuzi Xixin decoction and Xiaoqinglong decoction.Conclusion:The prescriptions containing Aconiti lateralis radix praeparata developed by Pro. Zhao are widely used in pediatric pulmonary disease syndrome. The prescription medication is more concentrated, and the combination method is clear.

Key words:

Aconiti lateralis radix praeparata, Data mining, Association rules