消积理脾散与厌食贴联合常规治疗儿童厌食症（脾失健运证）的临床观察

doi:10.20274/j.cnki.issn.1674-3865.2025.06.001

Abstract

Abstract:

Objective To observe the efficacy of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia of spleen dysfunction syndrome, as well as its effects on TCM syndrome scores, trace elements and hemoglobin in children. Methods A total of 86 children with anorexia who visited the Pediatric Outpatient Department of Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from October 2023 to December 2024 were selected as research subjects. They were randomly divided into a control group and an observation group, with 43 cases in each group. Both groups were treated with oral lysine inositol vitamin B₁₂ oral liquid, while the observation group was additionally given Xiaoji Lipi powder and anorexia plaster. Both groups received a 4-week course of treatment. TCM syndrome scores, efficacy, trace elements(Zn, Fe, Ca), hemoglobin and adverse reactions were compared between the two groups. Results The effective rate of the observation group was 95.35%(41/43), which was higher than 81.40%(35/43) of the control group, and there was a statistically significant difference(P<0.05). After treatment, the scores of symptoms, such as poor appetite, reduced food intake, hiccups and belching, abdominal distension, sallow complexion and irregular defecation, as well as the total scores in both groups were significantly lower than those before treatment；moreover, the improvement of each symptom score and total score in the observation group was significantly better than that in the control group, there were statistically significant differences(P<0.05). After treatment, the levels of trace elements(Zn, Fe, Ca) and hemoglobin in both groups were significantly higher than those before treatment, and the improvement of each index in the observation group was significantly superior to that in the control group， there were statistically significant differences(P<0.05). There was no statistically significant difference in adverse reactions between the two groups(P>0.05). Conclusion The application of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia of spleen dysfunction syndrome can significantly improve appetite, increase food intake, and promote the recovery of nutritional status and the absorption of trace elements. It is significantly effective, safe and reliable, and is worthy of promotion.

Key words: Anorexia, Spleen dysfunction syndrome, Xiaoji Lipi powder, Anorexia plaster, Lysine inositol vitamin B₁₂, Child

CLC Number:

R442.1

Ruiqi CAI, Oumei HAO, Xuefeng WANG, Kexin ZHANG. Clinical observation of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia(spleen dysfunction syndrome)[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(6): 461-465.

Figures/Tables 3

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Table 2

Table 3

References 30

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组别	n	食欲不振		食量减少		呃逆嗳气		腹胀
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	43	3.67±1.44	1.40±1.48^a	3.86±1.41	1.16±1.25^a	1.47±0.86	0.65±0.81^a	1.60±0.82	0.63±0.73^a
观察组	43	3.86±1.41	0.70±1.15^a	3.81±1.44	0.42±0.82^a	1.37±0.85	0.30±0.56^a	1.56±0.83	0.33±0.52^a
t值		-0.61	2.44	0.15	3.26	0.51	2.32	0.26	2.22
P值		0.550	0.017	0.880	0.002	0.613	0.023	0.794	0.029
组别	n	面色少华		大便失调		形体消瘦		总积分
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	43	1.44±0.91	0.67±0.84^a	1.86±0.89	0.98±0.94^a	2.05±0.82	1.79±0.71^a	14.09±3.87	5.23±4.50^a
观察组	43	1.47±0.88	0.33±0.57^a	1.81±0.98	0.47±0.67^a	2.00±0.82	1.44±0.67^a	13.88±3.81	2.53±2.99^a
t值		-0.12	2.26	0.23	2.91	0.25	2.35	0.25	3.28
P值		0.904	0.027	0.820	0.005	0.800	0.021	0.801	0.002

组别	n	痊愈	显效	有效	无效	总有效
对照组	43	11(25.58)	11(25.58)	13(30.23)	8(18.60)	35（81.40）
观察组	43	19(44.19)	16(37.21)	6(13.95)	2(4.65)	41（95.35）^a

组别	n	血清Zn（μmol/L）		血清Ca（mmol/L）		血清Fe（μmol/L）		血红蛋白（g/L）
组别	n	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后	治疗前	治疗后
对照组	43	10.60±1.35	15.89±1.93^a	1.55±0.13	1.81±0.14^a	7.38±0.49	8.88±0.36^a	110.25±8.24	120.15±8.21^a
观察组	43	10.25±1.06	17.42±2.11^a	1.50±0.14	1.90±0.12^a	7.49±0.47	9.14±0.50^a	110.64±8.19	124.84±7.84^a
t值		1.32	-3.52	1.56	-3.05	-1.06	-2.78	-0.22	-2.71
P值		0.189	0.001	0.123	0.003	0.292	0.007	0.827	0.008

Clinical observation of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia(spleen dysfunction syndrome)

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