Abstract: Vitamin D metabolism is complicated, and the probability of vitamin D deficiency in pregnant women is still relatively high, which is becoming a hot research area. The transfer of vitamin D in the placenta occurs mainly during the third trimester of pregnancy, so premature infants are at higher risk of vitamin D deficiency. However, the heart, brain and lung functions of preterm infants are not mature. There are many previous studies on the association of vitamin D with calcium, phosphorus and metabolic bone diseases. Recent rat studies have shown that maternal vitamin D deficiency leads to changes in cardiomyocytes, nerve cells and alveolar epithelial cells. This review aims to explore the relationship between vitamin D and heart, brain and lung diseases, in order to provide new ideas for the prevention and treatment of heart, brain and lung diseases in premature infants.

Key words:

Vitamin D, Premature infants, Cardiac function, Neonatal hypoxic-ischemic encephalopathy, Neonatal respiratory distress syndrome, Bronchopulmonary dysplasia in premature infants