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Effect of compound Danshen injection on concentration of plasma lysophosphatidic acid in children with viral encephalitis and its significance WANG Yun Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 447-450.   DOI: 10.3969/j.issn.1674-3865.2015.05.014 Abstract （761）      PDF（pc） （454KB）（1799）       Knowledge map    Save Objective：To investigate the effect of compound Danshen injection on concentration of plasma lysophosphatidic acid in children with viral encephalitis and its significance. Methods：A total of 98 cases of viral encephalitis in children were randomly divided into the observation group and the control group (49 cases in each). The control group was given conventional treatment, and the observation group was treated with compound Danshen injection in addition to the treatment for the control group. Compare the change of the concentration of plasma lysophosphatidic acid and coagulation indexes of the two groups before and after treatment, and analyze the therapeutic effect in the two groups. Results：The total effective rate of observation group(95.92%) was significantly higher than that of control group (73.47%) ( P＜0.05); the indexes of the two groups had statistically significant difference at different times after treatment(P＜0.05). Conclusion：Compound Danshen injection can significantly improve the concentration of plasma lysophosphatidic acid in children with viral encephalitis, and thus improve the therapeutic effect, which is beneficial to disease remission. Related Articles | Metrics

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Observation on the clinical efficacy of Xiaoer Chiqiao Qingre granule for herpangina in children ZHANG Hua Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (6): 584-586.   DOI: 10.3969/j.issn.1674-3865.2015.06.017 Abstract （797）      PDF（pc） （416KB）（1573）       Knowledge map    Save Objective：To observe the clinical curative effect and drug safety of Xiaoer Chiqiao Qingre granule in the treatment of child herpangina. Methods：A total of 156 cases of herpangina were randomly divided into control group and observation group, with 78 cases in each group. The control group was given conventional treatment of ribavirin antiviral therapy, while the observation group was given Xiaoer Chiqiao Qingre granule on the basis of ribavirin antiviral treatment；observe the clinical efficacy and drug safety of the two schemes. Results：The total effective rate of observation group was 96.2%(75/78), which was significantly higher than the 84.6% of control group(66/78), the difference being statistically significant (P＜0.05).The time for appetite to return to normal had no statistically significant difference between the two groups(P＞0.05). The incidence of drug reactions was 3.8%(3/78) in the control group, and compared with the 5.1%(4/78) of observation group, there was no statistically significant difference(P＞0.05). Conclusion：The scheme of combining Xiaoer Chiqiao Qingre granules with the conventional antiviral treatment to treat child herpangina has quick and significant effect, and its drug safety is not lower than conventional antiviral drugs. Related Articles | Metrics

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Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution WANG Qi, WANG Xuefeng, ZHAO Xia, LI Min Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (4): 277-282.   DOI: 10.3969/j.issn.1674-3865.2023.04.001 Abstract （625）      PDF（pc） （857KB）（1553）       Knowledge map    Save Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution Research Committee of World Federation of Chinese Medicine Societies Related Articles | Metrics

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Clinical study on treatment for malocclusion during primary dentition with INFANT TRAINER YU Peng Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 475-478.   DOI: 10.3969/j.issn.1674-3865.2015.05.024 Abstract （819）      PDF（pc） （482KB）（1543）       Knowledge map    Save Objective：To study the clinical effects of INFANT TRAINER appliance on malocclusion in primary dentition. Methods：Ten patients with Class II malocclusion and 8 patients with Class Ⅲ malocclusion were treated with INFANT TRAINER. Overjet and overbite changes and bad oral habit of before and after treatment were observed and analysed. Results ：Patients who were with INFANT TRAINER compliance had their teeth aligned，deep overjet and deep overbite corrected，and facial profile improved 6 months later． Conclusion：INFANT TRAINER appliance is effective in treating malocclusion with deep overjet and deep overbite in primary dentition．It is important for doctors and parents to encourage and guide children to wear the appliance correctly and on time. Related Articles | Metrics

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Observation on the results of comprehensive nursing intervention in autumn diarrhea in infants and young children WANG Hongling Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 534-537.   DOI: 10.3969/j.issn.1674-3865.2015.05.048 Abstract （686）      PDF（pc） （571KB）（1507）       Knowledge map    Save ObjectiveTo observe the clinical effect of comprehensive nursing intervention in autumn diarrhea in infants and young children.MethodsTotally 120 cases of autumn diarrhea in infants were randomly divided into observation group and control group with 60 cases in each group. In addition to conventional symptomatic treatment，routine nursing was given to the control group，while comprehensive nursing was given to the observation group. The total efficiency, satisfaction rate, length of hospital stay and costs were compared.ResultsThe satisfaction rate of children in observation group was 98.3%(59/60), and the total effective rate was 96.7%(58/60), which were significantly higher than 83.3%(50/60) and 83.3% (50/60) in the control group，the difference being statistically significant(P＜0.05); and in the observation group hospitalization costs were lower and hospital stay was shorter than the control group, the difference being statistically significant(P＜0.05).Conclusion Comprehensive nursing intervention can improve overall efficacy in children with diarrhea who receive symptomatic treatment, and it can also improve nursing satisfaction, which should be introduced. Related Articles | Metrics

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Diagnosis and treatment thoughts and intervention misunderstanding of infantile developmental retardation SONG Hujie，WANG Hui，REN Yongjia，LI Fangfang Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 416-420.   DOI: 10.3969/j.issn.1674-3865.2015.05.002 Abstract （956）      PDF（pc） （697KB）（1436）       Knowledge map    Save Based on the clinical characteristics of infantile developmental retardation, the author reviewed and summarized literature on etiology, classification, diagnosis, treatment, rehabilitation and problems easily ignored of children with developmental delays. Infantile developmental retardation is with diverse clinical manifestations, complex etiology and difficult diagnosis, which requires early detection, early diagnosis and early intervention. Related Articles | Metrics

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Experiences of Dachengqi decoction in treating children with sweating disease of stomach-burning type ZHANG Xiaobo, SHI Huijuan Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (1): 88-90.   DOI: 10.3969/j.issn.1674-3865.2017.01.027 Abstract （661）      PDF（pc） （454KB）（1392）       Knowledge map    Save Sweat is one of the products of human metabolism, which is commonly seen in hot weather or due to too much clothing or violent activities sweating disease in children is an abnormal disease, which is believed to be mainly deficiency syndrome in the traditional Chinese medicine concept. Excess syndrome is also observed in clinical practice and the type of stomach heat burnings more common. Giving priority to Dachengqi decoction in the treatment based on syndrome differentiation is utilized in the clinic. The effect is remarkable. Here is a test case. Related Articles | Metrics

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Experience on the treatment for infantile attention-deficit hyperactivity disorder by Chinese medicine DING Lizhong，LI Chunjuan, JIN Dongming Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 502-504.   DOI: 10.3969/j.issn.1674-3865.2015.05.034 Abstract （859）      PDF（pc） （422KB）（1390）       Knowledge map    Save ADHD is a common behavior disorder in childhood. Professor Jin Dongming thinks that the syndrome of stagnated heat of liver and stomach is one of important syndromes of the disease, so the treatment should be to relieve liver and lung. Baihu decoction and peony liquorice decoction were selected as alternative treatment. Besides, paying attention to protection of liquid, and keeping the Yin and proper use of Schisandra chinensis has achieved good effect. Related Articles | Metrics

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Analysis of the death cause in congenital hypertrophic pyloric stenosis ZOU Chanjuan，LI Bixiang，ZHOU Chonggao，WANG Haiyang，XU Guang，XIA Renpeng Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 440-443.   DOI: 10.3969/j.issn.1674-3865.2015.05.011 Abstract （853）      PDF（pc） （503KB）（1389）       Knowledge map    Save Objective：To analyze the data of the death cause in congenital hypertrophic pyloric stenosis in order to improve the survival rate. Methods：Totally 626 patients diagnosed with HPS were analyzed, 602 cases underwent laparoscopic pyloromyotomy and cured, 20 cases were discharged from hospital without operation, and 4 cases died, the cure rate being 96.16%. For the 4 death cases, we analyzed the clinical characteristics and causes of death. Results:The 4 deaths occurred after operation：2 cases died after operation because of cardiorespiratory function failure，and 1 case died from hyperkalemia. The surgical wound bleeding occurred in 1 patient after operation, and there was a sudden death in the treatment. Conclusion:The main causes of death of HPS are severe infection, internal metabolic disorders, stress reaction after operation, and improper feeding. Paying high attention to the prevention and managing actively can reduce the fatality. The key to successful recovery is the control of infection, electrolyte disturbance correction, and improved nutrition in preoperative period, and careful and comprehensive treatment and prevention of stress reaction during and after operation. Related Articles | Metrics

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Effect observation of large-dose vitamin C in treating acute glomerulonephritis in children WANG Yong, FANG Hongxing, SUN Yajun, LIU Huimin Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 450-453.   DOI: 10.3969/j.issn.1674-3865.2015.05.015 Abstract （824）      PDF（pc） （444KB）（1346）       Knowledge map    Save Objective：To investigate the clinical effect of large-dose vitamin C in treating acute glomerulonephritis. Methods：Eighty cases of acute glomerulonephritis were divided into control group and observation group, 40 cases in each group. The control group was given conventional western medicine and observation group was given large-dose vitamin C in addition to the conventional western medicine. After 4 weeks of treatment, observe the extinction of edema,blood sedimentation, routine urine test and complement change of the two groups. Results：Total effective rate of the two groups had no statistical significance(P＞0.05). Cure rate of observation group was 70.0%(28/40), higher than control group(47.5%，19/40), the difference being statistically significant(P＜0.05). Extinction of edema, blood sedimentation, routine urine test and complement of observation group had shorter recovery time than control group, the difference being statistically significant(P＜0.05). Conclusion：Large-dose vitamin C plays an important role in the treatment of acute glomerulonephritis. It is worthy of wide application. Related Articles | Metrics

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Experience in treating pediatric diseases by Siya Sanxian decoction LIU Shangjian, ZHOU Yuanhang, CAI Jiang, XU Rongqian Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 508-511.   DOI: 10.3969/j.issn.1674-3865.2015.05.037 Abstract （1057）      PDF（pc） （594KB）（1296）       Knowledge map    Save Professor Xu Rongqian is a famous expert in traditional Chinese medicine and is the guidance teacher of academic experience inheritance. With 36 years of clinical experience, Professor Xu is good at treating all kind of pediatric diseases. Based on many years of clinical summary and deep analysis of child physiology, he has created Siya Sanxian decoction under the guidance of the Shaoyang theory. The function of the decoction is to eliminate the stagnation and promote the spleen. It has remarkable curative effect in treating pediatric diseases. Related Articles | Metrics

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Individualized intervention strategies in the treatment of childhood and adolescent obesity based on precision medicine LI Ping, YANG Fan, LIU Hanmin Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 1-7.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.001 Abstract （775）      PDF（pc） （1165KB）（1269）       Knowledge map    Save Childhood and adolescent obesity has become a global challenge in public health.Its high weight regain rate and risks of metabolic complications highlight the limitations of traditional intervention strategies.This review systematically explores individualized intervention strategies for obesity in children and adolescents in the context of precision medicine,breaking the traditional "one-size-fits-all" model.It integrates multi-omics technologies with intelligent management methods,proposing a multidimensional framework for precise intervention.First,a precise diagnosis and evaluation system is constructed based on multi-modal data,including genomics,radiomics,and gut microbiomics,to identify genetic susceptibility,metabolic phenotypes and microbiome characteristics,laying the foundation for stratified interventions.Secondly,individualized intervention plans are developed based on genetic risk scores,epigenetic regulatory mechanisms,and gut microbiome-targeted therapies:gene-guided strategies aim to optimize dietary structure through multi-gene risk assessments; epigenetic interventions aim to regulate DNA methylation and histone modification by taking advantage of nutrients (such as methyl donors and short-chain fatty acids),reversing metabolic dysregulation; microbiome remodeling aims to improve energy metabolism balance through probiotics and synbiotics.Furthermore,artificial intelligence and wearable devices are employed for dynamic monitoring in multiple scenarios.By collaborating with multidisciplinary teams in nutrition,sports medicine,and psychology,a smart management model of "hospital-family-community" network is established.While precision medicine offers groundbreaking directions for childhood obesity treatment,challenges such as biomarker validation,data integration,and long-term efficacy evaluation remain to be addressed.This review provides theoretical foundations and practical pathways for the improvement in the effectiveness and sustainability of interventions,emphasizing the need to integrate interdisciplinary innovative technologies in the future in order to promote the transformation of childhood obesity management toward precision and intelligence. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2014, 6 (4): 356-358.   DOI: 10.3969/j.issn.16743865.2014.04.031 Abstract （389）      PDF（pc） （381KB）（1245）       Knowledge map    Save Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2013, 5 (4): 292-294.   DOI: 10.3969/j.issn.1674-3865.2013.04.002 Abstract （326）      PDF（pc） （464KB）（1233）       Knowledge map    Save Related Articles | Metrics

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Assessment and diagnosis of global developmental delay LI Runjie，WANG Chun Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 420-423.   DOI: 10.3969/j.issn.1674-3865.2015.05.003 Abstract （1041）      PDF（pc） （579KB）（1181）       Knowledge map    Save Global development delay (GDD) has various causes，whose diagnosis is difficult. Cause analysis of GDD is helpful to evaluate the prognosis of patients，assess morbidity of siblings and perform targeted intervention to specific cases. This article mainly summarizes clinical assessment of GDD (medical history，physical examination，etc)，cause analysis (metabolic assessment，genetic assessment，etc) and imaging assessment based on latest literatures，thus generating comprehensive diagnosis，which helps to perform treatment aiming at causes and early-stage rehabilitation to improve prognosis of patients. Related Articles | Metrics

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Current research of traditional Chinese medicine on ADHD in children HAN Xinmin Chinese Pediatrics of Integrated Traditional and Western Medicine    2016, 8 (5): 465-467.   DOI: 10.3969/j.issn.1674-3865.2016.05.001 Abstract （827）      PDF（pc） （372KB）（1139）       Knowledge map    Save In this paper, we analyzed the evolution of TCM name of ADHD, clinical and experimental research, characteristics and advantages，and deficiencies and prospects. Although there are many clinical reports, most of them lack strict design, without multicentric, randomized, controlled and large-sample clinical research. In the recent 10 years, the research projects supported by National Natural Science Foundation of China haven't obtained ground-breaking progress. The advantages of TCM treatment for ADHD are individualized diagnosis and therapy, syndrome differentiation treatment, integral regulation and restoration of the function of the internal organs. In order to make greater innovative achievements, it is necessary to conduct further research and standardize experiment through cooperation. Related Articles | Metrics

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Clinical study of scalp acupuncture combined with transcranial ultrasound therapy and language training for children with mental retardation and language disorder WANG Xue Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (2): 93-.   DOI: 10.3969/j.issn.1674-3865.2021.02.001 Abstract （603）      PDF（pc） （507KB）（1059）       Knowledge map    Save Objective：To explore the effect of Scalp acupuncture with transcranial ultrasound therapy combined with language training in the treatment of children with mental retardation and language disorder.Methods：Totally 90 children with mental retardation and language disorder who were admitted to our hospital from June 1,2018 to December 31,2019 were selected as the study subjects. According to the order of admission, they were divided into test group, control group 1 and control group 2,30 cases each. Control group 1 was treated with traditional language cognitive training, Control Group 2 was treated with scalp acupuncture on the basis of language training, and test group was additionally treated with transcranial ultrasound therapy.Results：The intelligence level and language function of 3 groups were improved; the total effective rate of control group 2 was higher than that of control group 1, and the total effective rate of observation group was significantly higher than that of control group 1 and control group 2; all the differences were of statistical significance.Conclusion：Scalp acupuncture with transcranial ultrasound therapy combined with language training is significantly effective in the treatment of children with mental retardation and language disorder. Related Articles | Metrics

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Clonazepam for intramuscular injection and enema in the treatment of infantile convulsion：curative effect observation HUANG Ling Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 445-448.   DOI: 10.3969/j.issn.1674-3865.2015.05.013 Abstract （1202）      PDF（pc） （438KB）（1055）       Knowledge map    Save Objective：To observe the clinical effect and safety of clonazepam for intramuscular injection and enema in the treatment of infantile convulsion. Methods：Ninety children with convulsion were randomly divided into 3 groups：group of clonazepam for intramuscular injection(A)，group of clonazepam for enema (B) and control group(C)，with 30 cases in each.Group A was given clonazepam at 0.05 mg/kg for intramuscular injection；group B was given clonazepam at 0.1 mg/kg for enema；control group was given luminal at 5 mg/kg for intramuscular injection.Observe the treatment results and adverse reactions. Results： Total effective rate was 90.0%(27/30) in both group A and group B，which was 63.3%(19/30) in group C，the difference being of statistical significance(P＜0.017).There was no significant difference between group A and group B(P＞0.017).There was no relapse in either group A or B，while there were 8 cases of relapse in group C.There was no respiratory depression or circulation disorder in all the 3 groups after treatment. Conclusion：Clonazepam for intramuscular injection and enema is effective in the treatment of infantile convulsion.It is safe and easy to perform with no adverse reaction，which is worthy of being applied in the local hospitals. Related Articles | Metrics

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Intervention effect of health management with traditional Chinese medicine on children with Qi-deficient constitution(recurrent cold) DUAN Zheng, WANG Zhuo Chinese Pediatrics of Integrated Traditional and Western Medicine    2022, 14 (1): 68-72.   DOI: 10.3969/j.issn.1674-3865.2022.01.017 Abstract （166）      PDF（pc） （803KB）（1049）       Knowledge map    Save Objective To provide evidence for the clinical effect of health management with traditional Chinese medicine on children with Qi-deficient constitution (recurrent cold). Methods A total of 68 cases of children with Qi-deficient constitution (recurrent cold) were selected, who were treated in Henan TCM Hospital. Formulate intervention regimen of TCM health management (including diet, living, sports, massage, herbal tea and foot bath), and health education was regularly carried out for the guardians of children. Management time was 4 months, the follow-up period was 1 year, and clinical efficacy was observed before management, and after the 4th month, the 8th month, and the 12th month, including the changes in symptom score of Qi-deficient constitution, the effective rate of constitution improvement and changes in number of colds. Results (1) Through TCM health management, at different time points in a year (after the 4th month, the 8th month, the 12th month), individual symptom score and total score of Qi-deficient constitution were lower than those before management(P<0.001); the number of colds was significantly less than before(P<0.001). (2) After the 12th month, there were 68 cases whose rate of decrease in total score of clinical manifestations of Qi-deficient constitution was no more than 30%, and the effective rate of TCM health management in physical improvement of Qi-deficient constitution was 100%.Conclusion The effect of TCM health management intervention on children with Qi-deficient constitution is significant, which can effectively improve the Qi-deficient constitution and reduce the incidence of cold. TCM health management intervention for children with Qi-deficient constitution(recurrent cold) has a long-term effect. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2010, 2 (1): 56-58.   DOI: 10.3969/j.issn.1674-3865.2010.01.024 Abstract （305）      PDF（pc） （397KB）（1047）       Knowledge map    Save Related Articles | Metrics