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Biostime probiotics combined with compound Huangbai solution in treatment of childhood eczema: an observation on the efficacy LI Fangfang Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (2): 121-123.   DOI: 10.3969/j.issn.1674-3865.2017.02.009 Abstract （762）      PDF（pc） （327KB）（347）       Knowledge map    Save Objective：To investigate the clinical efficacy of biostime probiotics combined with compound Huangbai solution in the treatment of eczema in children． Methods：Totally 82 children with eczema treated in our hospital from Aug. 2014 to Jan. 2016 were selected as the subjects, and they were randomly divided into two groups: observation group(A) and control group(B),41 children in each group. Group A was given biostime probiotics combined with external treatment of Huangbai solution，while Group B was only given external treatment of Huangbai solution．The eczema area, EASI scores and the clinical curative effect of two groups were observed after two weeks of treatment． Results：After the treatment of one week and two weeks, the EASI scores were statistically different between the two groups(P<0.05),and the curative effect of Group A was better than that of Group B. The total effective rate in Group A and B was 92.1% and 65.7%, respectively and the difference was statistical(P<0.05)． Conclusion：For children with eczema, the treatment of oral biostime probiotics combined with compound Huangbai solution for external use can achieve significant effect． Related Articles | Metrics

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Influencing factors of hyperbilirubinemia in preterm infants MU Huaixin，LI Juan Chinese Pediatrics of Integrated Traditional and Western Medicine    2018, 10 (1): 56-58.   DOI: 10.3969/j.issn.1674-3865.2018.01.016 Abstract （546）      PDF（pc） （325KB）（350）       Knowledge map    Save Objective To study the influencing factors of hyperbilirubinemia in preterm infants. Methods A total of 237 cases of preterm infants under 37 weeks of gestational age diagnosed with hyperbilirubinemia were selected, who received phototherapy in Shengjing Hospital of China Medical University from June 2013 to Dec. 2016, and they were included as the observation group. A total of 142 preterm infants without hyperbilirubinemia hospitalized during the same period were chosen as the control group. Compare the gestational factors of the mothers，  the general condition of the preterm infants and their relationship with the diseases in preterm infants between the two groups. Results The cesarean section rate of observation group was 43.5%（103/237）， the rate of 1 min Apgar score≤7 was 22.8%（54/237）， and the rate of time of first meconium＞24 h was 27.4%（65/237）， all being higher than those of control group（25.4%,11.3% and 17.6%，respectively）， and there was statistical difference（P<0.05）. The incidence rate of acidosis（18.6%，44/237），neonatal sepsis（EOS/LOS）（8.4%,20/237）, neonatal hemolysis disease(5.9%,14/237), and suppurative meningitis(2.53%,6/237) was significantly higher than that of control group(18.3%,0.7%,1.4% and 0.7%, respectively), the difference being statistical(P<0.05). The gestational age of the observation group［(33.8±2.1)weeks］ and the birth weight［(2 259±515)g］ were significantly lower than the control group（P<0.05）. The hemoglobin level［(170±21)g/L］ was higher in the observation group than in control group［(163±22)g/L］(P<0.05). Multi-factor Logistic regression analysis showed that the 1 min Apgar score≤7（OR=8.189，P<0.05）, cesarean section（OR=2.461，P<0.05）， the time of first meconium>24 h（OR=3.214，P<0.05）, neonatal sepsis（EOS/LOS）（OR=45.385，P<0.05）， and high level of hemoglobin（OR=1.024，P<0.05） were the risk factors of hyperbilirubinemia in preterm infants. Conclusion Many perinatal factors can lead to hyperbilirubinemia in the preterm infants. It will reduce the incidence of hyperbilirubinemia in preterm infants to improve delivery technique， detect early and give timely gastrointestinal feeding. Related Articles | Metrics

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Clinical study of scalp acupuncture combined with transcranial ultrasound therapy and language training for children with mental retardation and language disorder WANG Xue Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (2): 93-.   Abstract （414）      PDF（pc） （507KB）（421）       Knowledge map    Save Objective：To explore the effect of Scalp acupuncture with transcranial ultrasound therapy combined with language training in the treatment of children with mental retardation and language disorder. Methods：Totally 90 children with mental retardation and language disorder who were admitted to our hospital from June 1,2018 to December 31,2019 were selected as the study subjects. According to the order of admission, they were divided into test group, control group 1 and control group 2,30 cases each. Control group 1 was treated with traditional language cognitive training, Control Group 2 was treated with scalp acupuncture on the basis of language training, and test group was additionally treated with transcranial ultrasound therapy. Results：The intelligence level and language function of 3 groups were improved; the total effective rate of control group 2 was higher than that of control group 1, and the total effective rate of observation group was significantly higher than that of control group 1 and control group 2; all the differences were of statistical significance. Conclusion：Scalp acupuncture with transcranial ultrasound therapy combined with language training is significantly effective in the treatment of children with mental retardation and language disorder. Related Articles | Metrics

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Observation of clinical effect of Bifid Triple Viable Capsules Dissolving at Intestines combined with smecta in treatment of infantile diarrhea LIU Weiping, LIAO Chaoping, CHEN Yanli Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (1): 44-46.   DOI: 10.3969/j.issn.1674-3865.2017.01.013 Abstract （476）      PDF（pc） （373KB）（350）       Knowledge map    Save Objective: To observe the effect of Bifid Triple Viable Capsules Dissolving at Intestines combined with smecta in treatment of infantile diarrhea. Methods: Totally 98 cases of children with diarrhea who accepted treatments in Gangtou Community Health Service Center of Central Hospital of Longhua District of Shenzhen City from September 2014 to January 2016 were randomly divided into observation group and control group, with 49 cases in each group. The control group received routine therapy, while the observation group, on the basis of the treatment for the control group, were treated with the Bifid Triple Viable Capsules Dissolving at Intestines combined with smecta. Then, after 1 week of treatment, the treatment effect, recovery time and adverse reaction of two groups of patients were observed. Results: The total effective rate in the observation group was 91.8%(45/49), which was higher than the control group(75.5%, 37/49), and the difference was statistically significant(P<0.05). The recovery time of body temperature, stool frequency and stool character in the observation group was shorter than that in the control group, the difference being statistically significant(P<0.05). There was no serious adverse reaction in the two groups. Conclusion: The clinical effects of Bifid Triple Viable Capsules Dissolving at Intestines combined with smecta in treatment of infantile diarrhea are significant, which can quickly control the disease, reduce the pain of children, and the safety is high, thus it can be used as the preferred drug treatment for children with diarrhea. Related Articles | Metrics

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Nutritional status and influencing factors of 389 preschool children in Dadong District of Shenyang City LI Jinghui， REN Gang， ZHAN Jie， LI Jing， MA Lijie Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (4): 340-342.   DOI: 10.3969/j.issn.1674-3865.2017.04.021 Abstract （459）      PDF（pc） （337KB）（365）       Knowledge map    Save Objective To investigate the nutritional status of preschool children in 4 kindergartens in Shenyang City， and to provide reliable for nutritional intervention in preschool children. Methods Height and weight were measured and Kaup index was cakulated in 389 preschool children in Dadong District. The food types and eating habits were surveyed by questionnaires. Analyze the relationship between the related factors and the nutritional status of children. Results In 389 cases of children the average Kaup index was 16.30±2.07， and it was 16.45±1.87 in the boys and 16.12±2.27 in the girls；the index was normal in 346 cases. There were 41 lean cases and 2 cases a little fat. The questionnaires showed that the causes of malnutrition in children were mainly: hating fish， meat， eggs， soybean， etc.，being picky eaters，eating slowly，not having three meals on time，and wrong idea about nutrition in parents. Conclusion Some preschool children in Dadong District of Shenyang city have the phenomenon of malnutrition. Related Articles | Metrics

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Clinical observation on vegetative state of children with craniocerebral injury managed by acupoint electrical stimulation of median nerve ZHANG Ling，DUAN Hualin，QI Daili，LIU Yueyu，HU Li，DENG Ying Chinese Pediatrics of Integrated Traditional and Western Medicine    2019, 11 (4): 339-342.   DOI: 10.3969/j.issn.1674-3865.2019.04.017 Abstract （313）      PDF（pc） （581KB）（246）       Knowledge map    Save Objective To explore and analyze the vegetative state of children with craniocerebral injury managed by acupoint electrical stimulation of the median nerve. Methods Fifty children at vegetative state due to various causes were chosen, who were treated in Hunan Children's Hospital from Apr. 2013 to Apr. 2017. They were randomly divided into two groups: observation group(25) and control group(25). Both groups received routine comprehensive rehabilitation training. In addition, the observation group was given acupoint electrical stimulation of the median nerve, 30 min at a time, once a day, five days a week, for 6 courses in a row. The Glasgow Coma Measurement Scale(modified) was used to score in both groups. The children's EEG was monitored before and after treatment. Meanwhile, the mean flow velocity of middle cerebral artery(MCA) and basilar artery(BA) was determined by transcranial Doppler in thegroups. Results After treatment, the improvement in the EEG of observation group was better than that of control group(P<0.05). The Glasgow score was higher in both groups after treatment, and it was even higher in observation group than in control group(P<0.05). The mean flow velocity of the two kinds of arteries was significantly higher after treatment than before treatment in both groups, and it was higher in observation group than in control group(P<0.05). Conclusion The acupoint electrical stimulation of median nerve on the basis of routine treatment can play an effective role in promoting the arousal of the patients, which is beneficial to the rehabilitation and prognosis of children at vegetative state. Related Articles | Metrics

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Effects of Anti-disease Sachet(a type of Zhuang medicine) on the secretion of respiratory sIgA and IgG in Qi-deficiency mice WANG Lining，ZHANG Yixian，DENG Puyuan，LI Jie，ZHOU Zhining Chinese Pediatrics of Integrated Traditional and Western Medicine    2018, 10 (1): 6-8.   DOI: 10.3969/j.issn.1674-3865.2018.01.002 Abstract （572）      PDF（pc） （436KB）（323）       Knowledge map    Save Objective To study the effect of Anti-disease Sachet(a type of Zhuang medicine) on local immune function in Qi-deficiency mice, and to explore its mechanism in prevention and treatment of recurrent respiratory tract infection. Methods A total of 24 SPF mice of Kunming species were chosen(male and female), whose body mass was 18-22 g. They were randomly divided into four groups: blank group, model group, incense module group and sachet group, with 6 mice in each group. They were intervened by Anti-disease Sachet for 4 weeks, and at the fourth week, Qi-deficiency model was established; after that, ELISA was used to determine the concentration of sIgA and IgG in the alveolar lavage fluid. Results There was no statistical difference in sIgA in alveolar fluid between model group and sachet group(P>0.05). The sIgA in alveolar fluid of mice was significantly higher in sachet group than in blank group and model group, and there was statistical difference(P<0.05). There was no statistical difference in IgG in alveolar fluid of mice among the four groups(P>0.05). Conclusion Anti-disease Sachet(a type of Zhuang medicine) is effective in improving respiratory immune function, so it can be used to prevent recurrent respiratory tract infection in children. Related Articles | Metrics

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Experience on the treatment for infantile attention-deficit hyperactivity disorder by Chinese medicine DING Lizhong，LI Chunjuan, JIN Dongming Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 502-504.   DOI: 10.3969/j.issn.1674-3865.2015.05.034 Abstract （579）      PDF（pc） （422KB）（811）       Knowledge map    Save ADHD is a common behavior disorder in childhood. Professor Jin Dongming thinks that the syndrome of stagnated heat of liver and stomach is one of important syndromes of the disease, so the treatment should be to relieve liver and lung. Baihu decoction and peony liquorice decoction were selected as alternative treatment. Besides, paying attention to protection of liquid, and keeping the Yin and proper use of Schisandra chinensis has achieved good effect. Related Articles | Metrics

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Research progress of TCM treatment for functional abdominal pain in children MA Jinmei，CHEN Lu Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (4): 293-295.   DOI: 10.3969/j.issn.1674-3865.2017.04.006 Abstract （684）      PDF（pc） （311KB）（282）       Knowledge map    Save A lot of literatures have shown that western medicine has its limitation in the treatment of functional abdominal pain in children, which is mainly anti-infectious, anti-viral, sedative and anti-allergic treatments. In traditional Chinese medical treatment, there are many ways which by combining the internal with the external therapies, has achieved rapid effect, and also, there is no obvious adverse reaction. For external treatment, there are external application, acupunction, moxibustion, cupping, massage and chiropractic therapy. All these treatments are easy to perform and without side effects, and the compliance in children is comparatively high. However, there has been no consensus on TCM treatment due to the recognition difference, so it is necessary to look for more suitable and more accurate ways and to standardize the process of diagnosis and treatment. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (3): 207-212.   DOI: 10.3969/j.issn.1674-3865.2015.03.005 Abstract （298）      PDF（pc） （734KB）（232）       Knowledge map    Save Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2010, 2 (1): 56-58.   DOI: 10.3969/j.issn.1674-3865.2010.01.024 Abstract （229）      PDF（pc） （397KB）（202）       Knowledge map    Save Related Articles | Metrics

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Experience of Prof.She Jilin in treating children with Tourette syndrome QIN Shengjuan,WANG Chengjiao,SHE Jilin Chinese Pediatrics of Integrated Traditional and Western Medicine    2018, 10 (1): 90-92.   DOI: 10.3969/j.issn.1674-3865.2018.01.028 Abstract （1077）      PDF（pc） （482KB）（287）       Knowledge map    Save This paper briefly introduces Prof. She Jilin’s experience in the treatment of children with Tourette syndrome from the aspects of etiology, pathogenesis, treatment principles and prescriptions. At onset stage, the disease manifests as "Shi Zheng"(with the symptom of high fever, no sweat, abdominal distension, etc.), and the treatment aims to calm the liver wind, clear away heart-fire, nourish Yin and clear the heat. At remission stage, the disease manifests as "Xu Zheng"(deficiency syndrome), and the treatment focuses on invagrating spleen, nourishing Yin and Yang, calming liver wind and nourishing liver and kindey. Meanwhile, Prof. She also pays attention to psychological behavior intervention. Prof. She thinks that this disease in children most often is related to allergy, which makes more attacks at the turn of seasons and becomes more severe after catch a cold. During treatment, anti-allergic medicine should be given and pay attention to the regulation of lung, in order to strengthen the children's physical condition and improve the allergic situation of the children. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2013, 5 (4): 292-294.   DOI: 10.3969/j.issn.1674-3865.2013.04.002 Abstract （231）      PDF（pc） （464KB）（281）       Knowledge map    Save Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2014, 6 (3): 206-207.   DOI: 10.3969/j.issn.1674-3865.2014.03.006 Abstract （368）      PDF（pc） （328KB）（342）       Knowledge map    Save Related Articles | Metrics

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Analysis of epidemiology and drug resistance in 200 children with mycoplasma pneumonia WU Juntian, ZHANG Jiabin, ZHOU Shuming Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (2): 172-174.   DOI: 10.3969/j.issn.1674-3865.2017.02.027 Abstract （440）      PDF（pc） （312KB）（266）       Knowledge map    Save Objective：To analyze the epidemiology and drug resistance in 200 children with mycoplasma pneumonia and to provide reference for clinical treatment. Methods：Throat swabs were collected from 652 children with respiratory infection in out-patient department in our hospital. The swabs were cultured to detect MP. The MP infection was recorded according to seasons, ages and gender. The drug resistance to multiple antibiotics was detected. Results：MP culture showed that the positive rate was 30.67%;the infection rates in different seasons had differences, and the infection rate was the lowest in winter(15.00%), which was significantly lower than that in other seasons(P<0.05),and it was the highest in fall(38.50%);the infection rate in male children was slightly lower than the female patients(30.02% vs 31.80%,P>0.05);the infection rates in different age groups were significantly different(P<0.05):0-1-year-old group was higher than the 6-14-year-old group(P<0.008 3). Susceptibility test showed that drug resistance rates were significantly different to different antibiotics(P<0.05).ERY and ROX resistance rates were significantly higher than AZI(P<0.05). Conclusion：MP infection in children with respiratory tract infection has high proportion, which is age-related; it doesn't often occur in winter, and in the clinical treatment MP throat swab culture and drug sensitivity testing are required to guide the clinical administration. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (2): 100-104.   DOI: 10.3969/j.issn.1674-3865.2015.02.002 Abstract （331）      PDF（pc） （643KB）（233）       Knowledge map    Save Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (3): 195-198.   DOI: 10.3969/j.issn.1674-3865.2015.03.002 Abstract （277）      PDF（pc） （502KB）（221）       Knowledge map    Save Related Articles | Metrics

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Effect of Xiyanping injection on expression of Bcl-2/Bax protein in adenovirus-infected Hep-2 cells ZHANG Xiuying, WANG Xuefeng, WANG Siyuan, PING Jing. Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (2): 96-99.   DOI: 10.3969/j.issn.1674-3865.2017.02.002 Abstract （430）      PDF（pc） （474KB）（261）       Knowledge map    Save Objective:To explore mechanism of antiviral mechanism of Xiyanping injection in vitroby invstigating influence of  Xiyanping injection on expression of Bcl-2/Bax protein in adenovirus-infected Hep-2 cells. Methods:The Hep-2 cells were infected with adenovirus, which were interfered with high, medium and low dose of Xiyanping injection and ribavirin. Then expressions of Bcl-2/Bax protein were measured by immunohistochemistry. Results:The expressions of Bax protein in model group were significantly higher than normal groups（P<0.05）.The expression of Bax protein in all Xiyangping groups and ribavirin control group was lower than that of model group, and it was much lower in the high-dose Xiyanping group and ribavirin control group than in the model group(P<0.05). The expressions of Bal-2 protein in different groups had no significant difference（P>0.05）. ConclusionXiyanping injection can kill ADV by suppressing the expressions of Bax protein. The high-dose Xiyanping injection is better than others. Related Articles | Metrics

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Chinese Pediatrics of Integrated Traditional and Western Medicine    2010, 2 (4): 357-359.   Abstract （368）      PDF（pc） （360KB）（454）       Knowledge map    Save Related Articles | Metrics

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Infection situation of Mycoplasma pneumoniae in small infants with spastic cough and its treatment analysis WANG Jiangtao，WANG Xiaoling，LIU Rong Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (1): 40-43.   DOI: 10.3969/j.issn.1674-3865.2017.01.012 Abstract （516）      PDF（pc） （503KB）（300）       Knowledge map    Save Objective: To understand the infection status of mycoplasma pneumonia in 1-3-month children with spastic cough and analyse effect of macrolide drugs on spastic cough. Methods: A total of 235 cases of whooping cough syndrome in children were hospitalized for treatment from January 2015 to August 2016 in Zhengzhou Children's Hospital to different pathogens: Mycoplasma pneumoniae infection group(A，33 cases), non-Mycoplasma pneumoniae infection group(B,103 cases) and unknown pathogen group(C,99 cases). Direct immunofluorescence assay was used to detect the 7 common respiratory pathogenic antibodies. ELISA was performed to determine the titer of Mycoplasma pneumoniae antibodies in the serum at acute stage and recovery stage. Blood Agar was used to perform sputum bacteria culture. The children in group A and B were given cephalosporin and macrolides antibiotics, while those in group C were given cephalosporins, the treatment lasting 7 days. Observe the time for the spasmodic cough to disappear and the clinical effect in the children who came to hospital within 7 days of disease onset and after 7 days. Results: The pathogens of whooping cough syndrome were mostly viruses and bacteria; the detection rate of Mycoplasma pneumoniae was 14.04%(33/235).The spasmodic cough lasted for (5.79±0.89) days in the children visiting hospital within 7 days and their average hospital stay was (10.25±1.66) days, both of which were lower than the children who visited hospital for treatment 7 days after disease onset ［(10.38±2.00) days,(13.75±1.49) days］, and the difference being significant(P<0.05). The total effective rate in the 3 groups was respectively 93.94%(31/33), 91.26%(94/103) and 79.80%(79/99), and there was statistical difference(P<0.05). Conclusion: The pathogens of whooping cough syndrome are mostly viruses and bacteria. It can shorten the time of spasmodic cough and average hospital stay to visit hospital early, make early diagnosis and perform effective treatment. Cephalosporins are very effective in the treatment of whooping cough syndrome in small babies, but their abuse should be avoided. Related Articles | Metrics