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Professor Zhang Baoqing′s experience in treating children with tic disorder with Shenping decoction ZOU Zhiyun, SUI Xiaohui, ZHANG Baoqing. Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (3): 258-261.   DOI: 10.3969/j.issn.1674-3865.2024.03.016 Abstract （364）      PDF（pc） （1012KB）（17）       Knowledge map    Save The incidence of tic disorder has gradually increased in recent years， affecting the daily learning and life of children to varying degrees.In order to achieve better efficacy and reduce the adverse reactions caused by western medicine to the greatest extent， traditional Chinese medicine has gradually shown advantages in the treatment of this disease.This article introduces Professor Zhang Baoqing′s clinical experience in the treatment of children with tic disorder with Shenping decoction.Shenping decoction is from the book The Theory of Three Causes with One Prescription.Professor Zhang Baoqing believes that childhood tic disorder is located in the "liver"， which is closely related to the heart and lung， and the treatment should be based on stopping liver wind， taking the heart and lung into account.Professor Zhang combines the movement of Tiangan and the specific climate of Six Qi to flexibly use Shenping decoction in the treatment of children′s tic disorder,which has achieved remarkable effect.One case is attached for verification. Related Articles | Metrics

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Studies on short stature in Chinese and western medicine and the prospects YU Jian, WANG Na Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 372-376.   DOI: 10.3969/j.issn.1674-3865.2024.05.002 Abstract （298）      PDF（pc） （1076KB）（243）       Knowledge map    Save Short stature is affected by many congenital and acquired environmental factors, which involves every stage from pregnancy to adolescence. From the perspective of integrated Chinese and western medicine, this article systematically summarizes the definition and epidemiological features of short stature in clinical practice, as well as its diagnosis and treatment strategies in Chinese and western medicine. It is emphasized that a comprehensive intervention should be performed in order to scientifically cope with the issues on children's growth and development, especially short stature, which includes life style adjustment, nutritional regulation, exercise and sleep management. Researches have shown that the integrated Chinese and western medicine therapy can not only increase the growth rate of children's height effectively, but also adjust the constitution of children in a comprehensive way, which improves the general health level of children. This article aims to provide theoretical support and practical reference for future clinical management of short stature and not-up-tostandard stature. Related Articles | Metrics

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Expert consensus on the diagnosis and treatment of pharyngitis and tonsillitis in children WANG Xuefeng, SHANG Yunxiao, XIONG Lei, ZHANG Jianhua, QIN Yanhong, LIU Changshan, ZHANG Baoqing, CAO Ling, XU Hua, WANG Lining, YANG Nan, LI Miao, YANG Yungang, ZHANG Xiuying Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 399-403.   DOI: 10.3969/j.issn.1674-3865.2024.05.009 Abstract （277）      PDF（pc） （1047KB）（360）       Knowledge map    Save Pharyngitis and tonsillitis are common respiratory infectious diseases in childhood,and are highly prevalent in spring and fall.They can be categorized into acute and chronic stages.The acute stage is characterized by rapid onset and progression of the disease,and in severe cases,hoarseness and even respiratory difficulties may occur.In the chronic stage,the disease is prolonged due to the lack of proper treatment.Repeated pharyngitis and tonsillitis can lead to voice changes in children.At present,there are not many western medicines that can effectively treat childhood pharyngitis and tonsillitis,which are mainly antibiotic drugs,and although there are many types of traditional Chinese medicines used to clear the throat,western pediatricians are not standardized in the selection,syndrome differentiation and application of traditional Chinese medicines.Therefore,it is particularly important to explore the treatment for pharyngitis and tonsillitis in children with integrated Chinese and western medicine.This consensus firstly systematizes the Chinese and western medical understanding of pharyngitis and tonsillitis in children;secondly,it discusses its staging,etiology and main risk factors;thirdly,it clarifies its diagnostic criteria;finally,it gives a detailed elaboration on the principle of integrated Chinese and western medicine treatment for pharyngitis and tonsillitis in children and the Chinese and western medicine treatment methods.This consensus provides Chinese and western pediatricians,especially western physicians,with ideas on integrated Chinese and western medicine treatment,and further standardizes the rational selection and application of Chinese and western medicines. Related Articles | Metrics

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Current situation and prospect of TCM research in autism spectrum disorder ZHANG Yuehua, XIE Yuanyuan Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 301-304.   DOI: 10.3969/j.issn.1674-3865.2024.04.006 Abstract （269）      PDF（pc） （1073KB）（189）       Knowledge map    Save Autism spectrum disorder(ASD) is a group of neurodevelopmental disorders with a high rate of mental disability and an increasing incidence in recent years.The etiology of ASD is unknown,and there are no specific drugs or specific treatment methods.At present,the mainstream international treatment methods mainly rely on behavioral intervention and education to improve the core symptoms,and auxiliary drug therapy to improve the co-morbidity.In recent years,the research and exploration of TCM in the field of autism have been further.TCM therapy has unique advantages in improving the core disorders and comorbidities of autism,but it also faces difficulties and challenges.In this paper,the exploration of traditional Chinese medicine in the field of autism in recent years is reviewed to provide a certain theoretical basis and evidence for the treatment of autism by traditional Chinese medicine. Related Articles | Metrics

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Paying attention to the standardized diagnosis and treatment for children with short stature LUO Xiaoping, WU Wei Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 369-371.   DOI: 10.3969/j.issn.1674-3865.2024.05.001 Abstract （262）      PDF（pc） （1010KB）（230）       Knowledge map    Save Short stature has a significant impact on the physical and mental health of children, and it is a common disease in the endocrine department of pediatrics. Due to the rapid changes in children's growth and development and the complex etiology of short stature, there have always been such issues as missed diagnoses, misdiagnoses and insufficient intervention or overtreatment. This necessitates the strengthening of standardized diagnosis and treatment. This article discusses the challenges faced in the clinical diagnosis and treatment of children with short stature, especially emphasizing two aspects: one is to find out the etiology and make precise diagnosis, and the other is to perform individualized treatment strictly based on the indications. Meanwhile, the future direction of diagnosis and treatment of short stature is prospected, and suggestions are put forward for further standardization of diagnosis and treatment behavior of short stature, in order to provide useful reference for clinicians and policy makers. Related Articles | Metrics

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Traditional Chinese medicine understanding of short stature in children and syndrome differentiation and treatment for the disease WANG Xuefeng, ZHANG Xiuying Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 380-383.   DOI: 10.3969/j.issn.1674-3865.2024.05.004 Abstract （255）      PDF（pc） （1026KB）（432）       Knowledge map    Save Because children with short stature are shorter than children of the same age,they may suffer from low self-esteem,which seriously affects their mental health and has different degrees of impact on their future learning and lives.Traditional Chinese medicine has some advantages in the treatment of this disease because its syndrome differentiation and treatment can improve the growth and development of children.This paper first sorts out the historical development of short stature,which,as an independent name of the disease,was firstly seen in the textbook of Integrated Traditional Chinese and Western Medicine Pediatrics edited by Prof.Wang Xuefeng.Then,the etiology and mechanism of short stature are summarized.Its etiology is the deficiency of innate endowment and the lack of nutrition in later life.The disease is located in the spleen and kidneys,and it is closely related to the heart,liver and lungs. The nature of the disease is mostly deficiency.The primary mechanism of the disease is the deficiency of the five organs and the deficiency of essence and qi.The basic treatment principle is determined again,which is to support the spleen and nourish kidneys and also to take into account other organs.Among the treatment methods,the method of tonifying the kidneys and nourishing the liver is suitable to those with deficiency of yin in the liver and kidneys and loss of nourishment of the muscles and bones;the method of supporting the spleen and strengthening the stomach is suitable to those with weakness of the spleen and stomach and deficiency of qi and blood;the method of nourishing the kidneys and clearing the heart is suitable to those with deficiency of the heart and kidneys and imbalance of water and fire;the method of strengthening the spleen and nourishing the lungs is suitable to those with deficiency in the lungs and spleen and loss of qi of the mother;the method of warming and tonifying the kidney-yang is suitable to those with insufficiency of the kidney-yang and dysfunction of warming.Finally,the strategy of multi-dimensional care and prevention before the onset of disease is put forward.For children with short stature,attention should be paid to balanced nutrition,moderate increase in exercise,reasonable arrangement of sleep,and adjustment of the body in line with the four seasons. Related Articles | Metrics

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Diagnosis and treatment guideline for functional dyspepsia in children with the integrated traditional Chinese and western medicine WANG Xuefeng, WU Jie, GONG Sitang, XIONG Lei, JIANG Mizu, WANG Baoxi, XU Hua, PENG Yu Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (6): 461-468.   DOI: 10.3969/j.issn.1674-3865.2024.06.001 Abstract （250）      PDF（pc） （1049KB）（335）       Knowledge map    Save Functional dyspepsia,as one of the most common functional diseases of upper digestive tract,seriously affects the quality of life and growth and development of children in China.Due to the changing definition and symptom spectrum of functional dyspepsia in children,its diagnosis and treatment are controversial.In order to standardize the diagnosis and treatment of children with functional dyspepsia with integrated traditional Chinese and western medicine,and effectively solve the clinical problems in the diagnosis and treatment of children with functional dyspepsia,this guideline is formulated to guide the standardized diagnosis and treatment of children with functional dyspepsia with integrated traditional Chinese and western medicine. Related Articles | Metrics

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Experience and reflection on traditional Chinese medicine treatment for precocious puberty in children and impaired height XIONG Lei, HE Xiying, CAO Ting Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 377-379.   DOI: 10.3969/j.issn.1674-3865.2024.05.003 Abstract （245）      PDF（pc） （1016KB）（299）       Knowledge map    Save The clinical manifestation of precocious puberty is the premature development of secondary sexual characteristics, which can cause increased growth rate, rapid skeletal maturation, premature epiphyseal closure, etc. If not treated in time, it may cause children to be short in adulthood and increase the risk of endocrine diseases. Gonadotrophin releasing hormone analogue is the first choice in the treatment of this disease in western medicine, which can significantly inhibit the sexual development process by regulating the hypothalamicpituitarygonadal axis, but there is still controversy in terms of benefits to children's height. Traditional Chinese medicine therapy has been proven to be safe and effective in improving children's symptoms, regulating sex hormone levels, delaying gonadal development, improving height impairment, and increasing adult height. Professor Xiong Lei believes that the core pathological mechanism of this disease is kidneyyin deficiency and hyperactivity of liveryang fire. The treatment should be nourishing yin to strengthen the root, and lowering fire to clear sources. At the same time, for the patients with stagnated heat of liver channel, the method of dispersing stagnatedliver qi and clearing fire is used; for those with internal retention of phlegmdampness, the method of invigorating spleen to dissipate phlegm is used; for those with disharmony in the middle jiao, the method of invigorating spleen and harmonizing stomach is used. For children with rapid progression, gonadotrophin releasing hormone analogue can be used at the same time; for children with growth retardation and height impairment, recombinant human growth hormone should be considered to maximize their benefits to the height. Related Articles | Metrics

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Treatment for pediatric adenoid hypertrophy by Professor Ye Weicheng using Xu′s pediatric theory of strengthening the spleen and resolving phlegm and masses ZHOU Junhui, ZHAO Jun, YE Weicheng, CUI Chen Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 339-341.   DOI: 10.3969/j.issn.1674-3865.2024.04.014 Abstract （243）      PDF（pc） （1040KB）（139）       Knowledge map    Save The clinical incidence of adenoid hypertrophy in children is increasing year by year.At present,surgery is the first choice in clinical treatment,but the disease is likely to recur after surgery,and the patients often have adenoid facial expression and secretory otitis media;in severe cases,it may cause complications such as obstructive sleep apnea hypopnea syndrome,which may seriously affect the children′s growth,physical and mental health,and the quality of their lives in the long run.Professor Ye Weicheng applies Xu′s pediatric theory of strengthening the spleen and resolving phlegm and masses to the treatment of adenoid hypertrophy,and uses Erchen decoction to strengthen the spleen and resolve phlegm;in addition,Xia Ku Cao is used for resolving masses;the treatment has achieved great clinical effects. Related Articles | Metrics

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Application of external treatment of Chinese medicine in children's growth and development WANG Lining, SUN Kexing, LIANG Yi Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 384-387.   DOI: 10.3969/j.issn.1674-3865.2024.05.005 Abstract （239）      PDF（pc） （1006KB）（330）       Knowledge map    Save Short stature and not-up-to-standard stature belong to the category of "Wu Chi" and "Wu Ruan" in Chinese medicine, and Chinese medicine believes that the pathogenesis of them is deficiency in the spleen and kidney, which gets the heart and liver involved. External treatment of Chinese medicine is a unique natural and green therapy under the guidance of Chinese medicine theory, which has certain advantages in the treatment of short stature and not-up-to-standard stature. This article summarizes the treatment methods such as massage, acupuncture, moxibustion and acupoint application, as well as the mechanism of external treatment of Chinese medicine for children with short stature and not-up-to-standard stature, with a view to guide the early and timely clinical intervention, improve the function of children's internal organs and promote their growth and development. Related Articles | Metrics

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Expert consensus on traditional Chinese medicine intervention program for atopic dermatitis in children Zhao Yun, Ma Chunyan, Deng Dan, Wu Liqun, Zhang Huimin, Zhao Xia, Ye Qingyan, Zhu Shengguo, Yao Ting Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (3): 185-190.   DOI: 10.3969/j.issn.1674-3865.2024.03.001 Abstract （235）      PDF（pc） （851KB）（144）       Knowledge map    Save Atopic dermatitis in children is a common skin disease in infants and young children under the age of 3.Its recurrent itching and skin lesions affect the quality of life of the children.In order to further strengthen the clinical application and promotion of traditional Chinese medicine intervention in children with atopic dermatitis,the Pediatric Committee of Shanghai Association of Traditional Chinese Medicine and Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine have taken the lead in formulating this consensus,aiming to provide guidance for practitioners in traditional Chinese medicine pediatrics and better assist children. Related Articles | Metrics

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Effect of progressive resistance training on the activity and participation ability of children with spastic cerebral palsy SONG Fanxu, ZHAO Hongbo, PANG Wei Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 277-280.   DOI: 10.3969/j.issn.1674-3865.2024.04.001 Abstract （212）      PDF（pc） （1073KB）（16）       Knowledge map    Save Objective  To explore the effects of progressive resistance training on the activity and participation abilities of children with cerebral palsy at the ICF-CY level.Methods  The study subjects were 40 children with spastic diplegic cerebral palsy who were admitted to the Third Affiliated Hospital of Jiamusi University from January to December 2021.They were randomly divided into a control group and an observation group,with 20 cases in each group.The control group received routine rehabilitation training,while the observation group received progressive resistance training and routine rehabilitation training,with each group receiving treatment for 3 months.Before and after treatment,these children were evaluated for their activity and participation abilities using the Wee-FIM,PEDI,ADL,and TOP,respectively.Results  The Wee-FIM,PEDI,ADL,and TOP scores in the observation group were all higher than those in control group after treatment,and the differences were of statistical significance (P<0.05).Conclusion  The progressive resistance training can effectively improve the activity and participation ability of children with spastic diplegic cerebral palsy. Related Articles | Metrics

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An analysis of Professor Qin Yanhong′s experience in treating children with cough-variant asthma ZHANG Minjie, QIN Yanhong, ZHANG Sufeng Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 455-457.   DOI: 10.3969/j.issn.1674-3865.2024.05.020 Abstract （211）      PDF（pc） （1030KB）（78）       Knowledge map    Save Cough-variant asthma(CVA) is a common and frequently occurring respiratory disease in children.In recent years,with the aggravation of air pollution,the change in living habits and the increase in social pressure,the number of CVA cases in children is increasing year by year,which has a great impact on the physical and mental development of children and their social activities.Modern medicine is effective in treating CVA,but the treatment course is long and the compliance of children is low,which significantly increases the side effects.Traditional Chinese medicine treatment has the obvious advantages of definite curative effect and few side effects.Professor Qin Yanhong believes that the occurrence of CVA is the result of internal and external causes:the external evil is dominated by wind evil,and the internal cause is often the deficiency of lung and spleen in children.The key pathogenesis is the internal accumulation of wind sputum and the upward reversal of lung qi,and the pathological factors are mainly wind,sputum and qi,so the treatment emphasizes on dispersing wind,eliminating phlegm and regulating qi,and the self-designed "Zhike decoction" with modification is used to treat the disease.Due to the long course of CVA disease,and because the pathological focus of different periods is different,the treatment by stage is emphasized in clinical practice,the main treatment is to remove the evil during the attack period and to reinforce the deficiency and remove the evil during the recovery period.The effect is significant,and it is well recognized by parents. Related Articles | Metrics

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Research progress on external treatment of traditional Chinese medicine for children with sleep disorders LIU Wen, GUAN Lijun Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 410-413.   DOI: 10.3969/j.issn.1674-3865.2024.05.011 Abstract （207）      PDF（pc） （1030KB）（230）       Knowledge map    Save Sleep disorders have gradually become one of the common diseases in children,and sleep quality is very important for children′s growth and development.Traditional Chinese medicine has achieved remarkable results in the treatment of sleep disorders in children.Because of its safety,reliability,having no adverse reactions and simple operation,TCM external treatment is easy to be accepted by parents.This paper systematically sorts out the commonly used external treatment methods of Chinese medicine for children with sleep disorders,including acupuncture,acupoint application,massage and transcranial magnetic therapy,etc.,and summarizes and studies the relevant literature of these methods. Related Articles | Metrics

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Rehabilitation evaluation and treatment progress of hypotonia in infants and young children XU Haofan, ZHONG Zengquan, LAI Yanmei, LI Wei, ZHANG Xin, LI Hong, YANG Fan, LI Yiming, LYU Zhihai Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 414-419.   DOI: 10.3969/j.issn.1674-3865.2024.05.012 Abstract （203）      PDF（pc） （1091KB）（313）       Knowledge map    Save Hypomyotonia accompanied by growth retardation is an early symptom and sensitive sign of global developmental delay(GDD) in infants and young children,and is one of the early clinical manifestations of neurodevelopmental disorders and genetic metabolic diseases,which has a high incidence rate.According to the location of neuromuscular damage and involvement,hypotonia can be divided into three types:central hypotonia(CH),peripheral hypotonia(PH),or mixed hypotonia(MH).On the basis of etiological diagnosis of hypotonia,clinical evaluation and rehabilitation evaluation are conducted.Rehabilitation evaluation includes assessment of motor development level,developmental evaluation,evaluation of communication ability,and evaluation of daily life activity ability.Under the theoretical framework of the international classification of functioning,disability,and health(children and youth edition)(ICF-CY),the methods such as exercise therapy,traditional Chinese medicine rehabilitation,neuromuscular electrical stimulation,intramuscular patches,and assistant braces are adopted to promote the development of anti-gravity postures.Based on function-orientation and with the goal being to continuously improve activity and participation abilities,environmental factors such as rehabilitation aids are used to modify and improve the ability of daily life activities. Related Articles | Metrics

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Individualized intervention strategies in the treatment of childhood and adolescent obesity based on precision medicine LI Ping, YANG Fan, LIU Hanmin Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 1-7.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.001 Abstract （186）      PDF（pc） （1165KB）（195）       Knowledge map    Save Childhood and adolescent obesity has become a global challenge in public health.Its high weight regain rate and risks of metabolic complications highlight the limitations of traditional intervention strategies.This review systematically explores individualized intervention strategies for obesity in children and adolescents in the context of precision medicine,breaking the traditional "one-size-fits-all" model.It integrates multi-omics technologies with intelligent management methods,proposing a multidimensional framework for precise intervention.First,a precise diagnosis and evaluation system is constructed based on multi-modal data,including genomics,radiomics,and gut microbiomics,to identify genetic susceptibility,metabolic phenotypes and microbiome characteristics,laying the foundation for stratified interventions.Secondly,individualized intervention plans are developed based on genetic risk scores,epigenetic regulatory mechanisms,and gut microbiome-targeted therapies:gene-guided strategies aim to optimize dietary structure through multi-gene risk assessments; epigenetic interventions aim to regulate DNA methylation and histone modification by taking advantage of nutrients (such as methyl donors and short-chain fatty acids),reversing metabolic dysregulation; microbiome remodeling aims to improve energy metabolism balance through probiotics and synbiotics.Furthermore,artificial intelligence and wearable devices are employed for dynamic monitoring in multiple scenarios.By collaborating with multidisciplinary teams in nutrition,sports medicine,and psychology,a smart management model of "hospital-family-community" network is established.While precision medicine offers groundbreaking directions for childhood obesity treatment,challenges such as biomarker validation,data integration,and long-term efficacy evaluation remain to be addressed.This review provides theoretical foundations and practical pathways for the improvement in the effectiveness and sustainability of interventions,emphasizing the need to integrate interdisciplinary innovative technologies in the future in order to promote the transformation of childhood obesity management toward precision and intelligence. Related Articles | Metrics

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Effect of Chiqiao Qingre granules combined with cefuroxime in the treatment of acute respiratory tract infection in children and its influence on inflammatory factors MA Xiaodan, GAO Wenli, WANG Jiaojiao Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 444-448.   DOI: 10.3969/j.issn.1674-3865.2024.05.018 Abstract （184）      PDF（pc） （1066KB）（60）       Knowledge map    Save Objective：To explore the effect of Chiqiao Qingre granules combined with cefuroxime in the treatment of acute respiratory tract infection(ARTI) in children and its influence on inflammatory factors.Methods：A total of 103 children with ARTI admitted to our hospital from March 2021 to March 2023 were selected and divided into observation group(treated with Chiqiao Qingre granules combined with cefuroxime,n=52) and control group(treated with cefuroxime,n=51) according to different treatment methods.The clinical curative effect and symptom disappearance time of the two groups were observed,and the inflammatory factors,immune function and the incidence of adverse reactions of the two groups were compared.Results：After treatment,the total effective rate of the observation group was 90.4%(47/52),significantly higher than that of the control group(70.6%,36/51)(P<0.05).Compared with the control group,the disappearance time of fever and other symptoms,such as cough,dry throat,running nose and chest pain,in the observation group was significantly shorter(P<0.05).The levels of serum interleukin-6(IL-6),serum amyloid A(SAA),C-reactive protein(CRP) and procalcitonin(PCT) in the two groups were reduced,and the level in the observation group was lower than that in the control group(P<0.05).The Th1 and Th1/Th2 in the two groups were increased,and the Th1/Th2 in the observation group was higher than that in the control group(P<0.05).The Th2 in both groups was decreased,and the Th2 in the observation group was lower than that in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion：Chiqiao Qingre granules combined with cefuroxime is more effective in treating ARTI in children,which can speed up the disappearance of symptoms,relieve the body′s inflammatory response,and maintain immune balance,and it is safe and reliable. Related Articles | Metrics

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Research progress in the mechanism of Chinese medicine in the treatment of tic disorders based on network pharmacology ZHONG Mingxiu, ZHANG Di, LIU Ying Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 305-308.   DOI: 10.3969/j.issn.1674-3865.2024.04.007 Abstract （181）      PDF（pc） （1065KB）（20）       Knowledge map    Save With the development of society and the influence of the environment,the incidence of tic disorders (TD) has increased year by year in recent years,and it has become one of the more common pediatric diseases in clinical practice.The treatment for TD in western medicine is mainly based on dopamine (DA) and central α2 receptor agonists,combined with psychotherapy,which has certain efficacy,but its adverse reactions make some children intolerant.The holistic concept and treatment based on syndrome differentiation in traditional Chinese medicine have significant advantages in safety and efficacy in the prevention and treatment of TD.Single herbs,drug pairs and compounds in traditional Chinese medicine have multi-target and multi-pathway regulatory effects,which are consistent with the core idea of network pharmacology in modern theory.Therefore,network pharmacology methods are gradually being accepted and adopted by traditional Chinese medicine to study its mechanism of action.This paper reviews the research and application progress of network pharmacology in the mechanism of action of traditional Chinese medicine in the treatment of TD,and expounds the existing problems in the research,in order to provide reference for the application of network pharmacology in the research of traditional Chinese medicine in the treatment of TD. Related Articles | Metrics

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Meta-analysis of traditional Chinese medicine combined with recombinant human growth hormone in the treatment of children with idiopathic short stature WU Yishi, ZHANG Xiuying, LI Zhaoyang, WANG Xuefeng Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 425-430.   DOI: 10.3969/j.issn.1674-3865.2024.05.014 Abstract （175）      PDF（pc） （2283KB）（188）       Knowledge map    Save Objective：To systematically assess the clinical efficacy of traditional Chinese medicine in conjunction with recombinant human growth hormone, as well as that of recombinant human growth hormone alone, in the treatment of children with idiopathic short stature, thereby providing an evidence-based reference for clinical treatment. Methods：CNKI, VIP, Wanfang, CBM, and Pubmed were searched for literature that met the inclusion and exclusion criteria from the establishment of the database to September 30, 2024. RevMan 5.4 software was used for statistical analysis.Results：A total of 19 randomized controlled clinical trials with 1 756 patients were included, including 873 cases in the observation group and 883 cases in the control group. The results of Meta-analysis showed that the application of traditional Chinese medicine combined with recombinant human growth hormone in the treatment of idiopathic short stature was significantly better than the simple application of recombinant human growth hormone in improving the total effective rate, height, weight, growth rate, insulin-like growth factor 1 and insulin-like growth factor binding protein 3 levels, and the incidence of adverse reactions was lower than the simple application of recombinant human growth hormone.Conclusion：The integration of traditional Chinese medicine with recombinant human growth hormone demonstrates significant efficacy in the treatment of children with idiopathic short stature. Related Articles | Metrics

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Mechanism of inflammation in simple obesity and the treatment progress in Chinese and western medicine NIU Changmiao, YAN Xiaoning, YIN Yongkai, LIANG Liting Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 404-409.   DOI: 10.3969/j.issn.1674-3865.2024.05.010 Abstract （173）      PDF（pc） （1081KB）（234）       Knowledge map    Save Simple obesity refers to the fact that the body′s intake of energy is greater than the consumption of energy,which is accumulated in the body in the form of fat,resulting in the main clinical manifestation of obesity,and it can be accompanied by abnormal metabolism of glucose and lipid and endocrine disorders.Its incidence is increasing year by year,and it has become a serious social public health problem.Simple obesity is a chronic low-grade inflammatory state,and its mechanism is closely related to endoplasmic reticulum stress,mitochondrial dysfunction,oxidative stress,and macrophage polarisation in the body.For this disease,both Chinese medicine and western medicine have their intervention and treatment means,but modern medicine believes that the treatment for obesity is a combination of dietary and nutritional structural adjustment,exercise,psycho-psychological and medication,which requires a high level of execution and compliance of the patient,and the medication also has obvious side effects.Chinese medicine has a unique theoretical understanding of obesity,and Chinese medicine treatment also has its unique advantages.In this paper,we will make a review of the mechanism of adipose tissue inflammation in simple obesity and the current status of Chinese and western medicine treatment. Related Articles | Metrics