ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

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    Observation on the curative effect of Jianpi Yiqi ointment in treating anorexia(spleen and stomach qi-deficiency syndrome) in children
    Qimin TANG, Yishi TU
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 472-476.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.003
    Abstract1895)   HTML6)    PDF(pc) (595KB)(59)       Save

    Objective To explore the clinical effects of Jianpi Yiqi (tonifying spleen and benefiting qi) ointment in the treatment of pediatric anorexia (spleen stomach qi-deficiency syndrome). Method One hundred children with anorexia(spleen and stomach qi-deficiency syndrome) admitted to the Pediatric Department of Jingzhou Hospital of Traditional Chinese Medicine from January 2023 to February 2024 were selected as the research subjects, and they were randomly divided into a control group and an observation group, each consisting of 50 cases. The control group was treated with oral administration of Xingpi Yanger granules, while the observation group was treated with oral administration of Jianpi Yiqi ointment. The total effective rate of treatment, the excretion rate of urinary D-xylose, the ratio of salivary amylase activity, the levels of gastrin, motilin and neuropeptide Y, the improvement in symptom scores, and the body weight and height before and after treatment were observed and compared between the two groups. Results The total effective rate of treatment for children with anorexia(spleen and stomach qi-deficiency syndrome) in the observation group was 98.0%(49/50), significantly higher than that in the control group (84.0%, 42/50), with a statistically significant difference(P<0.05). After treatment, the urine D-xylose excretion rate, salivary amylase activity ratio, gastrin level, motilin level, and neuropeptide Y level in the observation group were higher than those in the control group, with statistically significant differences(P<0.05). After treatment, the symptom scores(food intake, appetite, and eating time) in the observation group were lower than those in the control group, with statistically significant differences(P<0.05). There was no statistically significant difference in body weight or height between the two groups before and after treatment(P>0.05). Conclusion Jianpi Yiqi ointment in the treatment of children with anorexia(spleen and stomach qi-deficiency syndrome) can significantly improve the therapeutic effect on the children, significantly improve a series of clinical indicators in them, and promote the relief of the clinical symptoms.

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    Traditional Chinese medicine theory of tic disorders comorbid with attention deficit hyperactivity disorder and the application
    Deqing NI, Jichao SUN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 512-516.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.009
    Abstract1876)   HTML6)    PDF(pc) (555KB)(58)       Save

    Tic disorders comorbid with attention deficit hyperactivity disorder (ADHD) is a common comorbidity of neurodevelopmental disorders in children. The core symptoms are motor/vocal tics, attention deficit and hyperactive impulsivity, which seriously affect the psychological and social functions of children. Atomoxetine and clonidine are the main drugs in western medicine treatment, but their clinical use is limited due to gastrointestinal and cardiovascular adverse reactions. Traditional Chinese medicines have the advantages of fewer adverse reactions and stable curative effect, which are easily accepted by the parents of children. For this disease, traditional Chinese medicine believes that its etiology is closely related to insufficient endowment, improper diet, emotional disorder, and invasion of external pathogens. The basic pathogenesis lies in the dysfunction of viscera and the imbalance of Yin and Yang, especially the "liver hyperactivity generating wind", which is the key. As a direct factor leading to tic symptoms, wind pathogen is often combined with sputum and fire and other pathological factors, forming a complex pathogenesis such as wind-sputum disturbance and wind-fire stimulation, which leads to the co-occurrence of tic symptoms with attention deficit and hyperactive impulse symptoms. Clinically, based on the pathogenesis, it can be divided into five main syndrome types: syndrome of liver wind carrying phlegm, syndrome of kidney deficiency and liver hyperactivity, syndrome of external wind causing activity, syndrome of latent fire in spleen and stomach and syndrome of heart and liver fire hyperactivity. The ultimate purpose of treatment is to harmonize Yin and Yang of viscera, and the core treatment principle of calming the liver and stopping wind is established. The pathological factors such as wind, phlegm and fire are concurrently managed according to the principle of "simultaneous application of principal and subordinate treatments". Based on different syndrome types, appropriate treatment principles and methods and prescriptions are selected for treatment.

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    Study on the assessment of "the TCM Constitution Scale for Children Aged 1+ to 7 Years"
    Xuefeng WANG, Qi WANG, Minghua BAI, Ji WANG, Hua XU, Lining WANG, Baoqing ZHANG, Zhenze CUI, Zhenqi WU, Xue ZHAO, Xiuying ZHANG, Xinyue KONG, Hao HE, Xinwei LIU
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 477-487.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.004
    Abstract1844)   HTML8)    PDF(pc) (578KB)(67)       Save

    Objective To test the reliability and validity of "the TCM Constitution Scale for Children Aged 1+ to 7 Years", and to optimize it. Methods Healthy children from 5 hospitals were selected for on-site inclusion. The reliability and validity of the scale were analyzed by means of decision value-critical ratio, item-total correlation method, Cronbach's α coefficient, split half reliability, retest reliability, and factor analysis,etc.,and the items with problems were summarized. Results Independent sample t-test was performed for the high and low subscales of 9 subscales, and the items of each subscale had t>3.000, P<0.05, without modification or deletion. Pearson correlation coefficient test was performed on 9 subscales, and the correlation coefficients of items Qi deficiency 9 and blood stasis 40 with the total score were all < 0.4, so it was considered to change or delete them. The Cronbach's α coefficient of the total scale and each subscale was >0.6, and the internal consistency was acceptable. After deleting items 5, 9, 13, 23, 29, 36, 40, 52, 58, 59, and 62, Cronbach's α coefficient increased, and it was considered to delete or change them. Principal component analysis was used to extract common factors based on eigenvalue greater than 1, and a total of 15 common factors were extracted, with a cumulative contribution rate of 62.226%. In order to further fit nine TCM constitution theories, the number of extraction factors was set at 9, and the cumulative contribution rate was shown to be 50.342%.In the structural validity analysis of each subscale, the one with 1 component had the dampness-heat quality and the peace quality; the one with 2 components had the Qi-deficiency quality, Yang-deficiency quality, phlegm-dampness quality, blood-stasis quality, Qi-stagnation quality and special quality subscale; the one with 3 components had the Yin-deficiency quality subscale. The factor loading for all subscale items was >0.4. Conclusion The reliability and validity of the "the TCM Constitution Scale for Children Aged 1+ to 7 Years" for the assessment of children's physical constitution are acceptable, but it still needs to be adjusted to improve its reliability and validity. Later, a discussion with relevant experts will be conducted, and the items with problems will be deleted or modified to form the second version of test of the "the TCM Constitution Scale for Children Aged 1+ to 7 Years", in order to make this scale more suitable for clinical identification of children's physical constitution.

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    Analyzing the experience in the treatment of children's tic disorders from the perspective of "liver collaterals"
    Yanqiu ZHOU, Aidong LIU, Xiaochun FENG, Xu YAN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 521-526.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.011
    Abstract1841)   HTML7)    PDF(pc) (676KB)(55)       Save

    In recent years, the incidence of tic disorders in pediatric clinical practice has been steadily increasing, emerging as a significant issue affecting the physical and mental development of affected children. This condition not only manifests as involuntary muscle tics or abnormal vocalizations but may also be accompanied by emotional and behavioral problems, directly impacting children's academic performance, daily life, and peer interactions. It urgently calls for collaborative attention from families, schools, and the healthcare institutions. Western medicine treatments may cause side effects such as sedation or drowsiness, and parents often worry about these adverse reactions and thus refuse to allow their children to take such medications. Traditional Chinese medicine (TCM) takes a different approach, proposing the concept of collaterals—organic pathways connecting internal organs and external limbs, and communicating between upper and lower parts of the body, which provides a unique perspective for TCM treatment. Based on the profound theoretical foundation of traditional Chinese medicine and rich clinical practice, the supervisor, Professor Feng Xiaochun, puts forward the academic idea of "differentiated treatment for children's diseases based on collaterals", and creatively believes that the core pathogenesis of the disease lies mainly in the "liver collateral imbalance", so the principle of its clinical treatment is to calm the liver and stop the wind and relax the tendons and promote the circulation. This is achieved by selecting herbal formulas with the effects of calming the liver, stopping wind, relieving spasms, and promoting circulation, while skillfully combining the external treatment of massage and herbal plaster application (Pingdong ointment), thus forming an integrated treatment system of "internal medication and external regulation" for childhood tic disorders. This approach has achieved significant therapeutic effects and advanced the prevention and treatment of childhood diseases from experience-based inheritance to precise intervention, bringing new insights to the prevention and treatment of childhood diseases.

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    Research advances in the treatment of pediatric epilepsy with Pingxian granules
    Yijue JING, Zhengyu YAO, Lü GAO
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 488-492.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.005
    Abstract1813)   HTML8)    PDF(pc) (577KB)(71)       Save

    Epilepsy, a chronic neurological disorder, has become a significant public health problem impacting children's health and development. Pingxian granules, formulated by Professor Zhang Shiqing, National Renowned TCM Physician, have gradually been proved in the effect on pediatric epilepsy, demonstrating substantial application potential and offering a novel therapeutic strategy in the treatment of pediatric epilepsy. Through sorting out the previous clinical and basic research results in the treatment of pediatric epilepsy by Pingxian granules, this paper discusses the mechanisms of action and development prospects, as well as current technical limitations, aiming to offer ideas for further exploring the therapeutic mechanism of Pingxian granules and provide reference for the prevention and treatment of pediatric epilepsy in traditional Chinese medicine.

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    Clinical observation of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia(spleen dysfunction syndrome)
    Ruiqi CAI, Oumei HAO, Xuefeng WANG, Kexin ZHANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 461-465.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.001
    Abstract1809)   HTML15)    PDF(pc) (567KB)(111)       Save

    Objective To observe the efficacy of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia of spleen dysfunction syndrome, as well as its effects on TCM syndrome scores, trace elements and hemoglobin in children. Methods A total of 86 children with anorexia who visited the Pediatric Outpatient Department of Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from October 2023 to December 2024 were selected as research subjects. They were randomly divided into a control group and an observation group, with 43 cases in each group. Both groups were treated with oral lysine inositol vitamin B12 oral liquid, while the observation group was additionally given Xiaoji Lipi powder and anorexia plaster. Both groups received a 4-week course of treatment. TCM syndrome scores, efficacy, trace elements(Zn, Fe, Ca), hemoglobin and adverse reactions were compared between the two groups. Results The effective rate of the observation group was 95.35%(41/43), which was higher than 81.40%(35/43) of the control group, and there was a statistically significant difference(P<0.05). After treatment, the scores of symptoms, such as poor appetite, reduced food intake, hiccups and belching, abdominal distension, sallow complexion and irregular defecation, as well as the total scores in both groups were significantly lower than those before treatment;moreover, the improvement of each symptom score and total score in the observation group was significantly better than that in the control group, there were statistically significant differences(P<0.05). After treatment, the levels of trace elements(Zn, Fe, Ca) and hemoglobin in both groups were significantly higher than those before treatment, and the improvement of each index in the observation group was significantly superior to that in the control group, there were statistically significant differences(P<0.05). There was no statistically significant difference in adverse reactions between the two groups(P>0.05). Conclusion The application of Xiaoji Lipi powder and anorexia plaster combined with conventional treatment for children with anorexia of spleen dysfunction syndrome can significantly improve appetite, increase food intake, and promote the recovery of nutritional status and the absorption of trace elements. It is significantly effective, safe and reliable, and is worthy of promotion.

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    Exploration of prescription patterns in Professor Wang Xiaoming's treatment for pediatric food accumulation and stagnation based on data mining
    Qing WANG, Yaqin CHEN, Danfei YIN, Suli WANG, Xiaoming WANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 466-471.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.002
    Abstract1801)   HTML6)    PDF(pc) (796KB)(58)       Save

    Objective To collate and analyze Professor Wang Xiaoming's traditional Chinese Medicine(TCM) prescriptions for pediatric food accumulation and stagnation, and summarize her clinical experience in medication for pediatric food accumulation and stagnation. Methods Prescription data from the outpatient department of Wang Xiaoming's Distinguished TCM Practitioner Studio in Zhejiang Province from January 1, 2019 to December 31, 2024 were collated and screened. Statistical software was employed to perform frequency analysis, analysis of medicinal properties (nature, flavor, channel tropism), analysis of medicinal efficacy, association rule analysis, and cluster analysis of the constituent herbs. Results A total of 382 prescriptions were screened out, identifying 19 high-frequency herbs. These herbs predominantly targeted the spleen, lung, stomach, and liver channels, with bitter, sweet, and pungent flavors being most common, and cold, warm, and neutral properties prevailing. The most frequently used herbs belonged to the categories of digestion-promoting, deficiency-tonifying and qi-regulating medicinals. The second-order association rule with the highest support was Fuling-Jineijin.The third-order association rule with the highest support was Baizhu-Fuling-Jineijin.Cluster analysis of high-frequency core herbs revealed two combinations. Conclusion Professor Wang's treatment for pediatric food accumulation and stagnation focuses on the core pathogenesis of "food accumulation leading to impaired spleen transportation, and qi stagnation, often accompanied by internal heat or liver qi stagnation." She establishes the core therapeutic principles of "promoting digestion and removing stagnation, strengthening the spleen and boosting qi, and regulating qi and harmonizing the middle Jiao." Innovatively, she emphasizes the simultaneous treatment of the liver and spleen and the clearance of stagnated heat.

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    Advances in diagnosis and treatment of pediatric mesenteric lymphadenitis based on integrated traditional Chinese and western medicine
    Minli GUAN, Xiaolin GAO
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 128-132.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.007
    Abstract1772)   HTML6)    PDF(pc) (595KB)(85)       Save

    Mesenteric lymphadenitis in children is a common pediatric abdominal pain disorder, which has the characteristics of repeated attacks and prolonged course of disease, seriously affecting the physical and mental health and quality of life of children. At present, there is no unified consensus on the diagnostic criteria and treatment of the disease. Anti-infection and symptomatic treatment are still the main clinical treatments, but long-term use of antibiotics can easily cause intestinal flora imbalance and drug resistance. In recent years, the role of probiotics in regulating intestinal microecology, reducing inflammation, shrinking lymph nodes, and assisting the treatment of children with mesenteric lymphadenitis has received increasing attention. The core treatment in traditional Chinese medicine (TCM) is regulating qi and relieving pain, reducing swelling and resolving nodules, and invigorating spleen and stomach, and various interventions are performed, such as oral administration of Chinese medicines, acupoint application, moxibustion and massage, which has achieved great effect. Integrated traditional Chinese and western medicine can synergistically enhance the effect, reduce the recurrence rate and improve the compliance, showing a good application prospect. This article systematically reviews the research progress in etiology, pathogenesis, key diagnostic points, western medicine treatment, traditional Chinese medicine treatment, integrated traditional Chinese and western medicine and probiotics application in children with mesenteric lymphadenitis, and sorts the limitations and controversies of current diagnosis and treatment, so as to provide references for standardized clinical diagnosis and treatment and subsequent researches.

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    Progress in traditional Chinese and western medicine treatments for idiopathic short stature
    Ruoyun REN, Wenqing YANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 498-502.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.007
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    Idiopathic short stature is a collective term for a group of highly heterogeneous conditions with unknown causes, primarily responsible for the short stature in children. If not promptly addressed, it can easily lead to psychological disorders and social adaptation difficulties in patients, significantly impacting their lifelong development quality. Currently, in western medicine, the core treatment approach is recombinant human growth hormone replacement therapy, supplemented by drugs that regulate the developmental process, such as gonadotropin-releasing hormone analogs and aromatase inhibitors. In traditional Chinese medicine, a syndrome-differentiated treatment system is employed, and internal administration of herbal medicines combined with external therapies of acupuncture, massage, and topical application of patches is used to promote bone growth, regulate endocrine metabolism, and improve physical condition, which demonstrates unique therapeutic effects and mechanism advantages.

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    Application of the "aromatic orifice-opening" method in pediatric pulmonary and nasal diseases
    Hang YANG, Mingzhang LI, Xi LI, Xinchen WU, Xiangjuan SUN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 147-151.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.011
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    "Aromatic orifice-opening" method has a long history and is widely used. Based on children's physiopathological characteristics and the theoretical basis of "the lung opens the orifices in the nose", the "aromatic orifices-opening" method is applied to children's pulmonary and nasal diseases, such as upper airway cough syndrome, allergic rhinitis, sinusitis, adenoid hypertrophy, etc. The causes and mechanisms of the diseases are explored in depth. Due to the nature of dispelling wind of aromatic products, such as Angelica dahurica, Atractylodes lancea, Agastache rugosa, etc., they are used to facilitate the opening of the nosal orifices, in order to promote the lung qi, relieve dampness and invigorate the spleen. The methods of warming yang and consolidating surface, activating blood circulation and removing blood stasis are also used. which result in good effects. A typical medical case is presented here for verification.

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    Etiology and pathogenesis of pediatric pneumonia from the perspective of the "Prolonged-Lying-Impairs-Qi" theory and the collaborative strategy of integrated Chinese-western medicine treatment
    Yuang LI, Kejin AN, Chuanqi ZHAO, Shirui SUN, Yuran WANG, Changqing SHEN, Na LI
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (5): 387-391.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.05.005
    Abstract1691)   HTML5)    PDF(pc) (671KB)(856)       Save

    Pediatric pneumonia progresses rapidly with a tendency of swift pathological changes, and prolonged lying with reduced activity is a significant intrinsic predisposing factor. Based on the traditional Chinese medicine (TCM) theory of "Prolonged Lying Impairs Qi" and considering the physiological characteristics of children——the delicate and immature viscera and underdeveloped Qi activity, this article systematically analyzes the mechanism by which "prolonged lying" damages the functional activities of Qi (Qi activity) in the lungs and spleen. It emphasizes the critical role of this mechanism in the onset, prolongation, and recovery of pediatric pneumonia. By integrating modern research, the article confirms that "prolonged lying" can reduce pulmonary function and immune levels, substantiating its pathogenic basis. Furthermore, it proposes an collaborative model of integrated Chinese-western medicine treatment, which combines infection control with TCM approaches of regulating Qi and reinforcing vital energy (Fuzheng) to improve symptoms and promote recovery. At the nursing level, we emphasize a trinity strategy of intervention: management of lying in bed, dietary therapy, and emotional support. Starting from the integration of traditional theory with modern evidence, this paper provides a systematic and feasible new approach to the prevention and treatment of pediatric pneumonia with integrated Chinese-western medicine.

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    Clinical efficacy analysis of foot bath with Jiebiao Toure decoction combined with meridian scraping in the treatment of exogenous fever (wind-heat type) in children
    Xuejiao WANG, Chen SHEN, Miao YU, Yiwen GAO, Heng LI
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 168-173.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.014
    Abstract1682)   HTML2)    PDF(pc) (638KB)(486)       Save

    Objective To explore the intervention effect of foot bath with Jiebiao Toure decoction (decoction for resolving symptoms and clearing heat) combined with meridian scraping on children with wind-heat-type exogenous fever. Method A total of 100 children with exogenous fever (wind-heat type) admitted to Pediatric Department of Affiliated Hospital of Changchun University of Chinese Medicine from April 2024 to October 2024 were selected and randomly divided into a control group and an observation group, each consisting of 50 cases. The control group received conventional treatment with western medicines, while the observation group received the treatment of foot bath with Jiebiao Toure decoction combined with meridian scraping in addition to the conventional western treatment. The total clinical effective rate after 3 days of treatment, changes in TCM symptom scores (red throat, nasal congestion, runny nose and cough), body temperature at each time point, time of complete defervescence, onset time of defervescence, frequency of antipyretic drug use, and average length of hospital stay were observed in both groups. Result There were 4 cases of loss of follow-up in the control group and 3 cases of dropping out in the observation group, and finally 93 patients completed the whole course of observation (46 in the control group and 47 in the observation group). The total effective rate was 89.4% (42/47) in the observation group, higher than the control group (71.7%, 33/46), and the difference was statistically significant(P<0.05). The symptom scores of red throat, runny nose and nasal congestion significantly decreased after treatment compared to before treatment, and the observation group was lower than the control group, with statistically significant difference(P<0.05). There was no statistically significant difference in symptom score of cough(P>0.05).The measurements at 1.5 h, 48 h and 72 h after treatment showed that the body temperature of the observation group was significantly lower than that of the control group, and all the differences were statistically significant(P<0.05). The time of complete defervescence, the onset time of defervescence and the average length of hospital stay were shorter in the observation group than in the control group, and the differences were statistically significant(P<0.01). There was no statistically significant difference in the frequency of antipyretic drug use between the two groups(P>0.05). Conclusion The combination of Chinese herbal medicine foot bath with meridian scraping can reduce the body temperature of children and improve clinical symptoms, has a significant antipyretic effect, and effectively shortens the treatment cycle.

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    Observation on the efficacy of pelvic floor magnetic stimulation combined with bladder function training in children with neurogenic bladder after spinal cord injury
    Yingying WU, Jinming LI, Caixiao SHI, Qing SHANG, Xiangli WANG, Liang HAN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 174-179.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.015
    Abstract1682)   HTML1)    PDF(pc) (591KB)(53)       Save

    Objective To explore the effects of pelvic floor magnetic stimulation combined with bladder function training on children with neurogenic bladder after spinal cord injury. Methods Sixty children with neurogenic bladder after spinal cord injury who were treated at Zhengzhou University Affiliated Children's Hospital from January 2023 to October 2025 were selected as the research subjects. According to the order of admission, 30 cases admitted from January 2023 to May 2024 were assigned to the control group, and 30 cases admitted from June 2024 to October 2025 were assigned to the observation group. The control group received conventional rehabilitation treatment, nursing measures, and bladder function training, while the observation group received pelvic floor magnetic stimulation in addition to the treatment for control group. The scores of voiding symptoms [core lower urinary tract symptom score (CLSS), urinary symptom distress scale (USDS)], neurogenic bladder symptom score (NBSS), and urodynamic indicator scores were compared between the two groups before and after the intervention. Results After the intervention, the CLSS, USDS, and NBSS of both groups were lower than those before the intervention, and the observation group was lower than the control group, with statistically significant differences(P<0.05). Concerning the urodynamic indicators, after the intervention, the maximum bladder capacity and internal bladder pressure of both groups were higher than those before the intervention, and the observation group was higher than the control group, with statistically significant differences(P<0.05); after the intervention, the residual urine volume of both groups was lower than that before the intervention, and the observation group was lower than the control group, with statistically significant differences(P<0.05). Conclusion Pelvic floor magnetic stimulation combined with bladder function training can improve the voiding symptoms of children with neurogenic bladder after spinal cord injury, relieve neurogenic bladder symptoms, and promote the recovery of urodynamic indicators, which has significant clinical effects and application value.

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    Research progress on influencing factors for childhood asthma control
    Lizheng JIN, Jiapei LIN, Hanyu SUN, Guangju HUANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 104-110.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.003
    Abstract1677)   HTML3)    PDF(pc) (676KB)(155)       Save

    Asthma is the most common chronic airway inflammatory disease in children, and its control status is closely related to the disease burden and prognosis. Despite the continuous advancement in diagnosis and treatment technologies, the control rate of childhood asthma globally and in China remains unsatisfactory. This article systematically elaborates on the factors affecting childhood asthma control from three aspects: first, discuss how the individual characteristics such as gender, obesity, comorbidities, etc. affect the asthma control physiologically; secondly, analyze how the environmental factors such as outdoor air pollution, indoor allergen exposure, tobacco exposure, and respiratory virus infections aggravate asthma symptoms; finally, the discussion focuses on management behaviors, especially the effect of treatment compliance and inhaler use techniques on asthma control. The aim is to provide a reference for accurately identifying high-risk factors and formulating individualized intervention strategies in clinical practice.

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    Exploring the mechanism and treatment of precocious puberty combined with obesity based on the theory of "Yang transforms qi and yin takes shape"
    Mengdi DENG, Guiju ZHANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 527-531.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.012
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    Precocious puberty in children shortens the period of growth and development and is associated with adverse long-term health outcomes. Obesity is an important risk factor for precocious puberty, and the two often coexist and their mechanisms are involved in each other. Based on the theory of "Yang transforms qi and yin takes shape" in Huangdi Neijing, Prof. Zhang Guiju proposes that the pathogenesis of obesity combined with precocious puberty is characterized by insufficient yang transforming qi and excessive yin taking shape in the early stage, excessive use of yang and loss of yin essence in the middle stage, and loss of yin involving yang and insufficient use of yang in the late stage. The treatment emphasizes the staged approach: at the early stage, warm and recuperate the spleen and kidney yang qi, transform phlegm dampness, and eliminate fat and turbidity; at the middle stage, nourish the kidney yin, clear and reduce the phlegm-fire, and dredge and regulate qi; at the late stage, tonify the kidney and fill up the essence, balance yin and yang, and regulate the vital organs. The whole process of eliminating phlegm dampness and fat and regulating qi and vital organs is aimed at warming yang and transforming qi to promote metabolism, nourishing yin and reducing fire to control hyperactivity of yang, tonifying the spleen and kidney to assist growth, and ultimately restoring the balance of yin and yang to ensure the normal developmental rhythms in children.

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    Experience of Professor Jia Liujin in treating pediatric pneumonia with dyspnea and cough
    Qing YANG, Jingnan XUE, Liujin JIA
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (2): 111-115.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.02.004
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    Professor Jia Liujin believes that lung qi depression and closure is the core mechanism of pediatric pneumonia with dyspnea and cough, and that relieving depression and opening up closure is the main method of treatment for this disease, so he proposes a sequential therapy that focuses on dispersing lung qi in the early stage, clearing in the middle stage, and tonifying in the late stage. The article also summarizes Professor Jia's experience in the diagnosis and treatment of pediatric pneumonia with dyspnea and cough, pointing out that it is important to focus on the identification of early pneumonia in the clinical diagnosis and treatment process, and summarizes the experience of using single and pair of medicines, which provides a reference for the clinical diagnosis and treatment of pediatric pneumonia with dyspnea and cough.

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    Experience of Professor Chang Ke in treating damp-heat syndrome of mycoplasma pneumoniae pneumonia in children with the method of dredging obstruction and resolving turbidity(Xuanbi Huazhuo)
    Jiayu LI, Yuan SUN, Xin FENG, Ke CHANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (5): 442-446.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.05.015
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    This paper summarizes Professor Chang Ke's experience in treating damp-heat syndrome of mycoplasma pneumoniae pneumonia in children with the method of Xuanbi Huazhuo. The core pathogenesis of this disease is that damp-heat stagnates and suppresses clear yang, condenses to form phlegm, and obstructs the lung collaterals. At the beginning, it is due to the stagnation of lung qi and failure in diffusion and descent, leading to the internal retention of dampness and fluid; then, the stagnated dampness turns into heat, which goes upward to the lungs; damp and heat binds together, generating phlegm and turbidity and blocking the lung collaterals, which is the key to the pathological changes. Eventually, damp, heat, phlegm and turbidity interacts with each other. Clinically, there are symptoms such as persistent fever, severe cough with much phlegm, nasal congestion, shortness of breath, chest tightness and phlegm congestion. Some children also have symptoms of damp-heat in the middle jiao, such as nausea and vomiting, poor appetite, yellowish-white or yellow-greasy tongue coating. In view of this, Xuanbi Huazhuo is the main treatment method. The self-made "Xuanjing decoction" is taken orally. It is composed of Shangjiao Xuanbi decoction (decoction for relieving obstruction in the upper Jiao) which can promote the flow of qi, resolve dampness and clear heat, combined with Qianjin Weijing decoction which can clear the lung, resolve phlegm, remove blood stasis and expel turbidity. Almond is added to enhance the functions of dispersing, descending and relieving cough, and talc is added to strengthen the clearing and draining of damp-heat. The whole prescription aims to dredge the obstruction of lung qi and clear away damp-heat, phlegm and turbidity. The empirical formula "Fuxiong powder" for external application helps to dredge the lung collaterals, warm and resolve phlegm and turbidity, disperse stagnation and promote qi flow. This treatment method focuses on the core of damp-heat, phlegm and turbidity obstructing the lung collaterals. It addresses the root cause of the stubborn turbidity by internally dredging the stagnation of qi in the lung collaterals; externally, it diffuses and penetrates through the skin, membranes and interstitial spaces, loosening the phlegm and blood stasis, thus launching a three-dimensional attack on "bi(obstruction)" and "zhuo(turbidity)". Clinical practice has confirmed that it can effectively relieve symptoms, which embodies the characteristics of traditional Chinese medicine in the treatment of this disease and the academic thoughts of Professor Chang Ke.

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    Professor Xiong Lei's experience in treating pediatric adenoid hypertrophy with aromatic herbs based on the theory of "Deficient Qi and Liquid Stagnation"
    Yi JIANG, Lei XIONG, Ting CAO, Yujiang XI
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (5): 451-456.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.05.017
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    Adenoid hypertrophy(AH) is a common pediatric disease characterized by pathological enlargement of the adenoid due to repeated stimulation of inflammation, causing symptoms such as nasal obstruction, snoring, and mouth breathing. It is often associated with obstructive sleep apnea and adenoid facial expression. Based on the theory of "Deficient Qi and Liquid Stagnation" and long-term clinical experience, Professor Xiong Lei proposes that the core pathogenesis of pediatric AH follows a "deficiency-rooted, stagnation-manifested" pattern. Professor Xiong thinks that the root cause of disease is the deficient qi of the lung, spleen and kidney, while the fluid stagnation of such pathological factors as phlegm, dampness and blood stasis is the disease manifestation, exacerbated by external pathogens. Considering the disease features of "deficiency in origin and excess in superficiality", the treatment principle emphasizes "tonifying deficiency, resolving stagnation, and regulating qi dynamics", with the management tailored to disease phases (acute, remission and chronic). Professor Xiong uses aromatic herbs to regulate qi and blood, and uses drug pairs to enhance the effect (agastache–Fritillaria thunbergii, Coix lacryma jobi–Ostrea gigas, and Paeonia lactiflora–Luffa cylindrica). Insect-derived drugs, such as silkworm larva and cicada slough, are also utilized for targeted treatment. By integrating the theory of "Deficient Qi and Fluid Stagnation" with aromatic therapy, this approach of Professor Xiong Lei simultaneously addresses dysfunction of the lung, spleen and kidney while resolving phlegm, dampness and stasis, providing a novel TCM strategy for the prevention and treatment of pediatric AH. A supporting case study is included to validate the clinical efficacy of this method.

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    Clinical experience of Professor Chang Ke in treating autism spectrum disorder in children with Xinyang decoction
    Xin FENG, Yuan SUN, Jiayu LI, Ke CHANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (6): 532-536.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.06.013
    Abstract1660)   HTML5)    PDF(pc) (608KB)(45)       Save

    Childhood autism spectrum disorder is a common mental and behavioral disorder in children. Taking the physiological and pathological characteristics of children into account, Professor Chang Ke analyzes the etiology and pathogenesis of autism spectrum disorder from four aspects: wind, phlegm, stasis and deficiency, and establishes the method of "searching for wind-eliminating phlegm-resolving stasis-replenishing deficiency", and emphasizes the importance of opening up the orifices in the treatment of this disease. Professor Chang Ke primarily employs his self-made formula—the Xinyang decoction—with modifications to treat symptoms associated with this condition. He further adjusts the formula based on the specific stage of the child's illness. Through syndrome differentiation, Professor Chang Ke focuses on expelling pathogenic factors (wind, phlegm, stasis) and opening up the orifices during the active phase of the disease, and during the remission phase, he emphasizes strengthening the body's vital energy (tonifying the kidneys and replenishing essence) to consolidate the foundation. This approach yields excellent therapeutic results, which offers new insights for the differentiated treatment for this condition in clinical TCM practice. One case is attached for verification.

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    Analysis of expert questionnaire on TCM syndromes of community-acquired pneumonia in children based on Delphi method
    Qian LIU, Xuefeng WANG, Xiuying ZHANG, Xinran FENG, Yanyan NI, Zhifan TIAN, Hui WANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (5): 410-417.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.05.009
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    Objective To investigate the diagnostic experience of experts on the syndrome of community-acquired pneumonia(CAP) in children by using the Delphi method, screen for the diagnostic indicators of syndromes, evaluate their importance, and provide evidence for the formulation of diagnostic standards for pediatric CAP. Methods Based on literature research, a questionnaire survey was conducted among selected experts using the Delphi method. The results of the questionnaire were statistically processed using Excel and SPSS 27.0 software, and the expert positive coefficient, expert authority coefficient, and the expert opinion coordination degree and concentration degree were calculated. Results A total of 30 domestic experts were selected for the questionnaire survey, with a questionnaire recovery rate of 90%. The expert authority coefficient was 0.905, and the expert coordination coefficient was 0.348(P<0.001). A total of 8 syndrome types were set up in the first round of expert questionnaire survey, including syndrome of heat pathogen blocking the lung, syndrome of lung and spleen-qi deficiency, syndrome of damp-heat blocking the lung, syndrome of wind-cold blocking the lung, syndrome of wind-heat blocking the lung, syndrome of toxic-heat blocking the lung, syndrome of phlegm-heat blocking the lung and syndrome of yin-deficiency with lung-heat, and their syndrome characteristics were analyzed. Conclusion This study initially explores the distribution pattern and characteristics of TCM syndromes in pediatric CAP, laying a foundation for subsequent researches on the diagnostic standards and clinical studies of TCM syndromes in pediatric CAP.

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