ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

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    Effect of compound Danshen injection on concentration of plasma lysophosphatidic acid in children with viral encephalitis and its significance
    WANG Yun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 447-450.   DOI: 10.3969/j.issn.1674-3865.2015.05.014
    Abstract684)      PDF(pc) (454KB)(1711)       Save

    Objective:
    To investigate the effect of compound Danshen injection on concentration of plasma lysophosphatidic acid in children with viral encephalitis and its significance.
    Methods:A total of 98 cases of viral encephalitis in children were randomly divided into the observation group and the control group (49 cases in each). The control group was given conventional treatment, and the observation group was treated with compound Danshen injection in addition to the treatment for the control group. Compare the change of the concentration of plasma lysophosphatidic acid and coagulation indexes of the two groups before and after treatment, and analyze the therapeutic effect in the two groups.
    Results:The total effective rate of observation group(95.92%) was significantly higher than that of control group (73.47%) ( P<0.05); the indexes of the two groups had statistically significant difference at different times after treatment(P<0.05).
    Conclusion:Compound Danshen injection can significantly improve the concentration of plasma lysophosphatidic acid in children with viral encephalitis, and thus improve the therapeutic effect, which is beneficial to disease remission.
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    Observation on the results of comprehensive nursing intervention in autumn diarrhea in infants and young children
    WANG Hongling
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 534-537.   DOI: 10.3969/j.issn.1674-3865.2015.05.048
    Abstract585)      PDF(pc) (571KB)(1496)       Save
    ObjectiveTo observe the clinical effect of comprehensive nursing intervention in autumn diarrhea in infants and young children.MethodsTotally 120 cases of autumn diarrhea in infants were randomly divided into observation group and control group with 60 cases in each group. In addition to conventional symptomatic treatment,routine nursing was given to the control group,while comprehensive nursing was given to the observation group. The total efficiency, satisfaction rate, length of hospital stay and costs were compared.ResultsThe satisfaction rate of children in observation group was 98.3%(59/60), and the total effective rate was 96.7%(58/60), which were significantly higher than 83.3%(50/60) and 83.3% (50/60) in the control group,the difference being statistically significant(P<0.05); and in the observation group hospitalization costs were lower and hospital stay was shorter than the control group, the difference being statistically significant(P<0.05).Conclusion Comprehensive nursing intervention can improve overall efficacy in children with diarrhea who receive symptomatic treatment, and it can also improve nursing satisfaction, which should be introduced.
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    Clinical study on treatment for malocclusion during primary dentition with INFANT TRAINER
    YU Peng
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 475-478.   DOI: 10.3969/j.issn.1674-3865.2015.05.024
    Abstract735)      PDF(pc) (482KB)(1424)       Save

    Objective:
    To study the clinical effects of INFANT TRAINER appliance on malocclusion in primary dentition.
    Methods:Ten patients with Class II malocclusion and 8 patients with Class Ⅲ malocclusion were treated with INFANT TRAINER. Overjet and overbite changes and bad oral habit of before and after treatment were observed and analysed.
    Results :Patients who were with INFANT TRAINER compliance had their teeth aligned,deep overjet and deep overbite corrected,and facial profile improved 6 months later.
    Conclusion:INFANT TRAINER appliance is effective in treating malocclusion with deep overjet and deep overbite in primary dentition.It is important for doctors and parents to encourage and guide children to wear the appliance correctly and on time.
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    Observation on the clinical efficacy of Xiaoer Chiqiao Qingre granule for herpangina in children
    ZHANG Hua
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (6): 584-586.   DOI: 10.3969/j.issn.1674-3865.2015.06.017
    Abstract662)      PDF(pc) (416KB)(1400)       Save

    Objective:To observe the clinical curative effect and drug safety of Xiaoer Chiqiao Qingre granule in the treatment of child herpangina.
    Methods:A total of 156 cases of herpangina were randomly divided into control group and observation group, with 78 cases in each group. The control group was given conventional treatment of ribavirin antiviral therapy, while the observation group was given Xiaoer Chiqiao Qingre granule on the basis of ribavirin antiviral treatment;observe the clinical efficacy and drug safety of the two schemes.
    Results:The total effective rate of observation group was 96.2%(75/78), which was significantly higher than the 84.6% of control group(66/78), the difference being statistically significant (P<0.05).The time for appetite to return to normal had no statistically significant difference between the two groups(P>0.05). The incidence of drug reactions was 3.8%(3/78) in the control group, and compared with the 5.1%(4/78) of observation group, there was no statistically significant difference(P>0.05).
    Conclusion:The scheme of combining Xiaoer Chiqiao Qingre granules with the conventional antiviral treatment to treat child herpangina has quick and significant effect, and its drug safety is not lower than conventional antiviral drugs.
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    Analysis of the death cause in congenital hypertrophic pyloric stenosis
    ZOU Chanjuan,LI Bixiang,ZHOU Chonggao,WANG Haiyang,XU Guang,XIA Renpeng
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 440-443.   DOI: 10.3969/j.issn.1674-3865.2015.05.011
    Abstract775)      PDF(pc) (503KB)(1330)       Save

    Objective:
    To analyze the data of the death cause in congenital hypertrophic pyloric stenosis in order to improve the survival rate.
    Methods:Totally 626 patients diagnosed with HPS were analyzed, 602 cases underwent laparoscopic pyloromyotomy and cured, 20 cases were discharged from hospital without operation, and 4 cases died, the cure rate being 96.16%. For the 4 death cases, we analyzed the clinical characteristics and causes of death.
    Results:The 4 deaths occurred after operation:2 cases died after operation because of cardiorespiratory function failure,and 1 case died from hyperkalemia. The surgical wound bleeding occurred in 1 patient after operation, and there was a sudden death in the treatment.
    Conclusion:The main causes of death of HPS are severe infection, internal metabolic disorders, stress reaction after operation, and improper feeding. Paying high attention to the prevention and managing actively can reduce the fatality. The key to successful recovery is the control of infection, electrolyte disturbance correction, and improved nutrition in preoperative period, and careful and comprehensive treatment and prevention of stress reaction during and after operation.
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    Experiences of Dachengqi decoction in treating children with sweating disease of stomach-burning type
    ZHANG Xiaobo,SHI Huijuan
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (1): 88-90.   DOI: 10.3969/j.issn.1674-3865.2017.01.027
    Abstract554)      PDF(pc) (454KB)(1305)       Save
    Sweat is one of the products of human metabolism, which is commonly seen in hot weather or due to too much clothing or violent activities sweating disease in children is an abnormal disease, which is believed to be mainly deficiency syndrome in the traditional Chinese medicine concept. Excess syndrome is also observed in clinical practice and the type of stomach heat burnings more common. Giving priority to Dachengqi decoction in the treatment based on syndrome differentiation is utilized in the clinic. The effect is remarkable. Here is a test case.
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    Diagnosis and treatment thoughts and intervention misunderstanding of infantile developmental retardation
    SONG Hujie,WANG Hui,REN Yongjia,LI Fangfang
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 416-420.   DOI: 10.3969/j.issn.1674-3865.2015.05.002
    Abstract866)      PDF(pc) (697KB)(1276)       Save

    Based on the clinical characteristics of infantile developmental retardation, the author reviewed and summarized literature on etiology, classification, diagnosis, treatment, rehabilitation and problems easily ignored of children with developmental delays. Infantile developmental retardation is with diverse clinical manifestations, complex etiology and difficult diagnosis, which requires early detection, early diagnosis and early intervention.
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    Experience in treating pediatric diseases by Siya Sanxian decoction
    LIU Shangjian, ZHOU Yuanhang, CAI Jiang, XU Rongqian
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 508-511.   DOI: 10.3969/j.issn.1674-3865.2015.05.037
    Abstract882)      PDF(pc) (594KB)(1270)       Save
    Professor Xu Rongqian is a famous expert in traditional Chinese medicine and is the guidance teacher of academic experience inheritance. With 36 years of clinical experience, Professor Xu is good at treating all kind of pediatric diseases. Based on many years of clinical summary and deep analysis of child physiology, he has created Siya Sanxian decoction under the guidance of the Shaoyang theory. The function of the decoction is to eliminate the stagnation and promote the spleen. It has remarkable curative effect in treating pediatric diseases.
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    Effect observation of large-dose vitamin C in treating acute glomerulonephritis in children
    WANG Yong, FANG Hongxing, SUN Yajun, LIU Huimin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 450-453.   DOI: 10.3969/j.issn.1674-3865.2015.05.015
    Abstract732)      PDF(pc) (444KB)(1259)       Save

    Objective:
    To investigate the clinical effect of large-dose vitamin C in treating acute glomerulonephritis.
    Methods:Eighty cases of acute glomerulonephritis were divided into control group and observation group, 40 cases in each group. The control group was given conventional western medicine and observation group was given large-dose vitamin C in addition to the conventional western medicine. After 4 weeks of treatment, observe the extinction of edema,blood sedimentation, routine urine test and complement change of the two groups.
    Results:Total effective rate of the two groups had no statistical significance(P>0.05). Cure rate of observation group was 70.0%(28/40), higher than control group(47.5%,19/40), the difference being statistically significant(P<0.05). Extinction of edema, blood sedimentation, routine urine test and complement of observation group had shorter recovery time than control group, the difference being statistically significant(P<0.05).
    Conclusion:Large-dose vitamin C plays an important role in the treatment of acute glomerulonephritis. It is worthy of wide application.
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    Experience on the treatment for infantile attention-deficit hyperactivity disorder by Chinese medicine
    DING Lizhong,LI Chunjuan, JIN Dongming
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 502-504.   DOI: 10.3969/j.issn.1674-3865.2015.05.034
    Abstract704)      PDF(pc) (422KB)(1187)       Save
    ADHD is a common behavior disorder in childhood. Professor Jin Dongming thinks that the syndrome of stagnated heat of liver and stomach is one of important syndromes of the disease, so the treatment should be to relieve liver and lung. Baihu decoction and peony liquorice decoction were selected as alternative treatment. Besides, paying attention to protection of liquid, and keeping the Yin and proper use of Schisandra chinensis has achieved good effect.
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    Assessment and diagnosis of global developmental delay
    LI Runjie,WANG Chun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 420-423.   DOI: 10.3969/j.issn.1674-3865.2015.05.003
    Abstract944)      PDF(pc) (579KB)(1045)       Save

    Global development delay (GDD) has various causes,whose diagnosis is difficult. Cause analysis of GDD is helpful to evaluate the prognosis of patients,assess morbidity of siblings and perform targeted intervention to specific cases. This article mainly summarizes clinical assessment of GDD (medical history,physical examination,etc),cause analysis (metabolic assessment,genetic assessment,etc) and imaging assessment based on latest literatures,thus generating comprehensive diagnosis,which helps to perform treatment aiming at causes and early-stage rehabilitation to improve prognosis of patients.
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    Clonazepam for intramuscular injection and enema in the treatment of infantile convulsion:curative effect observation
    HUANG Ling
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 445-448.   DOI: 10.3969/j.issn.1674-3865.2015.05.013
    Abstract1075)      PDF(pc) (438KB)(1042)       Save

    Objective:
    To observe the clinical effect and safety of clonazepam for intramuscular injection and enema in the treatment of infantile convulsion.
    Methods:Ninety children with convulsion were randomly divided into 3 groups:group of clonazepam for intramuscular injection(A),group of clonazepam for enema (B) and control group(C),with 30 cases in each.Group A was given clonazepam at 0.05 mg/kg for intramuscular injection;group B was given clonazepam at 0.1 mg/kg for enema;control group was given luminal at 5 mg/kg for intramuscular injection.Observe the treatment results and adverse reactions.
    Results: Total effective rate was 90.0%(27/30) in both group A and group B,which was 63.3%(19/30) in group C,the difference being of statistical significance(P<0.017).There was no significant difference between group A and group B(P>0.017).There was no relapse in either group A or B,while there were 8 cases of relapse in group C.There was no respiratory depression or circulation disorder in all the 3 groups after treatment.
    Conclusion:Clonazepam for intramuscular injection and enema is effective in the treatment of infantile convulsion.It is safe and easy to perform with no adverse reaction,which is worthy of being applied in the local hospitals.
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    Xiaoqinglong decoction in the treatment of infant wheezing:a clinical observation
    LI Xin,HE Weijia,XIANG Hong,YANG Kun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 465-468.   DOI: 10.3969/j.issn.1674-3865.2015.05.020
    Abstract963)      PDF(pc) (484KB)(971)       Save

    Objective:
    To observe the clinical curative effect of Xiaoqinglong decoction subtraction in the treatment of infant wheezing.
    Methods:Totally 120 cases of children with wheezing episodes were randomly divided into observation group and control group(n=60). Observation group was given Xiaoqinglong decoction;control group was treated with budesonide and compound ipratropium bromide atomization inhalation;compare clinical curative effect of two groups.
    Results:Seven days after treatment the clinical control rate of observation group was 83.3%(50/60), higher than the control group [63.3%(38/60)], the difference being statistically significant(P<0.05). The time for cough asthma and lung wheezing sound to disappear had no statistical difference(P>0.05);the time for lung phlegm sound to disappear in observation group was obviously shorter than the control group, the difference being statistically significant(P<0.05).
    Conclusion:Xiaoqinglong decoction is very effective in eliminating phlegm and relieving wheezing.
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    Evaluation of the recovery results and diagnosis of growth retardation in children
    MA Hongwei
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 413-417.   DOI: 10.3969/j.issn.1674-3865.2015.05.001
    Abstract841)      PDF(pc) (627KB)(948)       Save

    This paper introduced the evaluation of the recovery results and the diagnosis of growth retardation in children during rehabilitation training based on some cases.The results in some child patients were not in accordance with the expectation or the disease diagnosed,or some new manifestations appeared,when we needed to rethink about the previous diagnosis or to complete the diagnosis.For the children with growth retardation,we should pay attention to the special facial features,special posture,special movements or recession in some aspects.
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    Experimental research into the influence of Yiqi Guben capsule on the spleen lymphocyte proliferation function and organ index in the kidneyYang deficiency asthma model mice.
    CHEN Yueyuan,SUN Liping.
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2013, 5 (1): 12-16.   DOI: 10.3969/j.issn.1674-3865.2013.01.004
    Abstract334)      PDF(pc) (566KB)(905)       Save

    Objective:To observe the influence of Yiqi Guben capsule on the spleen lymphocyte proliferation function and organ index in the kidneyYang deficiency asthma model mice and to explore its clinical significance.MethodsTotally 96 mice were randomly divided into seven groups: normal control group, asthma group, the kidneyYang deficiency asthma group, kidneyqitonifying pill group, the Yiqi Guben capsule lowdose group, middledose group, highdose group. Apart from the asthma group consisting of 12 mice, the remaining groups each consisted of 14 mice(male and female in half). kidneyYang deficiency asthma groups were treated with Yiqi Guben capsule. Recorded changes in the general condition of the mice in each group during modeling and the period of administration, such as, body weight, body temperature and activity, hair color, diet, breathing frequency, etc. After the experiment, took the spleen and examined the lymphocyte proliferation function; took the kidney, spleen and thymus, and weighed them and calculated the organ coefficient.ReslutsIn the Yiq Guben capsule group and kidneyqitonifying pill group, the mice weight and thymus weight were significantly higher than the kidneyYang deficiency asthma group; in the Yiqi Guben capsule middledose group, the highdose group and kidneyqitonifying pill group, the spleen lymphocyte proliferation by LPS stimulation was significantly higher than the kidneyYang deficiency asthma group.ConclusionYiqi Guben capsule can significantly improve the general state of the kidneyYang deficiency asthma mice, restore immune organ weights, and improve the function of the spleen lymphocyte proliferation.
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    Treatment for children with diarrhea (spleen deficiency diarrhea):an experience discussion
    LIANG Shanshan,SUN Liping
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 504-506.   DOI: 10.3969/j.issn.1674-3865.2015.05.035
    Abstract917)      PDF(pc) (395KB)(891)       Save
    Infantile diarrhea is a common disease in pediatrics.Professor Sun Liping believes that the spleen dampness is the key to the occurrence of diarrhea.The diarrhea due to spleen deficiency is the most difficult to treat and mostly exists in infants and young children.Based on the principle of enhancirg spleen and removing dampness,Prof. Sun created Sanbai decoction Treatment for children with diarrhea, which may be added other medicines according to various symptoms and achieves great clinical curative effect.
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    Clinical study of scalp acupuncture combined with transcranial ultrasound therapy and language training for children with mental retardation and language disorder
    WANG Xue
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (2): 93-.   DOI: 10.3969/j.issn.1674-3865.2021.02.001
    Abstract499)      PDF(pc) (507KB)(882)       Save
    Objective:To explore the effect of Scalp acupuncture with transcranial ultrasound therapy combined with language training in the treatment of children with mental retardation and language disorder.Methods:Totally 90 children with mental retardation and language disorder who were admitted to our hospital from June 1,2018 to December 31,2019 were selected as the study subjects. According to the order of admission, they were divided into test group, control group 1 and control group 2,30 cases each. Control group 1 was treated with traditional language cognitive training, Control Group 2 was treated with scalp acupuncture on the basis of language training, and test group was additionally treated with transcranial ultrasound therapy.Results:The intelligence level and language function of 3 groups were improved; the total effective rate of control group 2 was higher than that of control group 1, and the total effective rate of observation group was significantly higher than that of control group 1 and control group 2; all the differences were of statistical significance.Conclusion:Scalp acupuncture with transcranial ultrasound therapy combined with language training is significantly effective in the treatment of children with mental retardation and language disorder.
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    The diagnostic value of brain natriuretic peptide (BNP) in infants with severe pneumonia complicated with heart failure
    HE Leifeng, YANG Ying, LIU Zhongqi, TAN Runguo, WANG Jinghui, DU Qiuping, CHEN Xianghong
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 494-497.   DOI: 10.3969/j.issn.1674-3865.2015.05.031
    Abstract652)      PDF(pc) (435KB)(874)       Save
    ObjectiveTo summarize the value of brain natriuretic peptide (BNP) in the diagnosis of severe pneumonia complicated with heart failure in infants.MethodsIn 100 cases of children clinically diagnosed with common pneumonia (group A) and 100 cases of children with severe pneumonia complicated with heart failure (group B)and 80 cases of children with severe pneumonia (no heart failure) group (C),the laboratory results were retrospectively analyzed.ResultsIn the three groups of children the abnormal rate of CK, CKMB (creatine kinase, creatine kinase isoenzyme), CTNI (troponin) and BNP had significant difference (P<0.01); further comparison showed that befween group A and group B serum CK, CKMB, CTNI and BNP were significantly different (P<0.01)in abnormal rate; between group A and group C abnormal rate of serum BNP had no obvious difference (P>0.05), but abnormal rate of CK, CKMB and CTNI of had obvious difference (P<0.01); between group B and group C abnormal rate of CK, CKMB and CTNI had no significant difference (P>0.05), but abnormal rate of BNP had obvious difference (P<0.01); in group B, after heart failure was corrected, BNP was restored to normal range.ConclusionBNP is a sensitive and special objective marker for infants with severe pneumonia complicated with heart failure.
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    Clinical research in Saccharomyces boulardii to prevent secondary diarrhea after surgical reduction for intussusception
    WEN Haitao
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2015, 7 (5): 480-483.   DOI: 10.3969/j.issn.1674-3865.2015.05.026
    Abstract700)      PDF(pc) (497KB)(845)       Save

    Objective:
    To observe the preventive effect of Saccharomyces boulardii on secondary diarrhea after surgical reduction for intussusception.
    Methods:The children receiving only emergency operative reduction for intussusception were randomly divided into the observation group (given boulardii) (94 cases)and the control group (no boulardii) (88 cases) after operation.. All of the patients were checked the stool occult blood and rotavirus antigen, and received other preoperative examinations. After operation conditions of the stool were paid attention to,and if diarrhea stool occult blood occurred,we immediately reexamined rotavirus antigen.
    Results:In the observation group and the control group the incidence of secondary diarrhea was 6.3% (6/94)and 12.5% (11/88)respectively, the difference between the two groups having statistical significance (χ2=4.63,P=0.03); postoperative time of diarrhea was (3.24±1.22) d and (4.63±1.14)d, the difference between the two groups having statistical significance (F=5.14, P=0.022). All patients were cured and discharged. There was no recurrence of intussusception, wound infection, dehiscence, allergies or other conditions, and the discharge stools were normal.
    Conclusion:Saccharomyces boulardii, in terms of the prevention of secondary diarrhea after surgical reduction for intussusception can be applied to treatment.
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    Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution
    WANG Qi, WANG Xuefeng, ZHAO Xia, LI Min
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (4): 277-282.   DOI: 10.3969/j.issn.1674-3865.2023.04.001
    Abstract327)      PDF(pc) (857KB)(841)       Save
    Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution Research Committee of World Federation of Chinese Medicine Societies
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