ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

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    Expert Consensus on the Prevention and Treatment of Children's Recurrent Respiratory Tract Infection by Integrating Traditional Chinese and Western MedicineRespiratory Group of Pediatric Committee of Chinese Association of Integrative Medicine
    Yunxiao Shang , Xuefeng Wang
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2022, 14 (6): 461-467.   DOI: 10.3969/j.issn.1674-3865.2022.06.001
    Abstract1535)      PDF(pc) (1482KB)(5445)       Save
    Recurrent respiratory tract infection is a common clinical phenomenon in children,which has a high incidence and brings a heavy burden to society and medical care,and has attracted much attention from pediatricians. The expert consensuses at home and abroad provided important guidance and suggestions for the diagnosis and treatment of children′s recurrent respiratory infections,but they were limited to the field of western medicine and did not include valuable experience in traditional Chinese medicine. The Expert Consensus on the Prevention and Treatment of Children′s Recurrent Respiratory Tract Infection by Integrating Traditional Chinese and Western Medicine integrates the traditional Chinese treatment based on syndrome differentiation with western medicine,revised repeatedly with reference to the latest guidelines,consensus and research progress of Chinese and Western medicine worldwide. This consensus will provide an important basis for pediatricians to reasonably integrate traditional Chinese and western medicine in the prevention and treatment of children′s recurrent respiratory infections.
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    Experience in the diagnosis and treatment of children's diseases from "accumulated internal heat"
    ZHANG Yu, XIAO Yang, ZHOU Mengxiao, SUN Liping
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 59-63.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.012
    Abstract2785)      PDF(pc) (1073KB)(5397)       Save
    The function of the spleen in children is often insufficient, and improper feeding, or disease damage may cause the fact that food can't be digested, which is food accumulation。Although it is a disease of the spleen, Professor Sun Liping believes that long time of food accumulation can form internal heat syndrome, thereby inducing a variety of pediatric diseases. Attention should be paid to the physical changes caused by congenital abnormality and acquired dystrophy. Based on the physiological and pathological characteristics of children, Yin and Yang theory, five-element theory and constitution theory, and through combination with more than 30 years of clinical experience of Professor Sun Liping, this paper explores the etiology and pathogenesis of children's diseases caused by "food", the disease outcome transformed by "heat", the diagnosis experience from "observation", and the treatment method by "elimination". A new line of thinking of "same treatment for different diseases" is provided for the diagnosis and treatment of abdominal pain, cough, asthma and tic disorders caused by food accumulation.
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    Meta analysis of the efficacy and safety of traditional Chinese patent medicine in the treatment of tic disorders in children
    LI Ruiben, NIE Lianghui, YANG Libin, MA Rong
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (6): 479-485.   DOI: 10.3969/j.issn.1674-3865.2023.06.004
    Abstract1346)      PDF(pc) (3684KB)(4426)       Save
    Objective To systematically evaluate the efficacy and safety of traditional Chinese patent medicine in the treatment of tic disorders in children.Methods Randomized controlled trials of traditional Chinese patent medicine in the treatment of tic disorders in children were comprehensively searched in CNKI,Wanfang Database,VIP,China Biomedical Database,Pubmed,Embase and Cochrane Library.Two independent researchers screened and evaluated the quality of the literature based on pre-set inclusion and exclusion criteria,and made a meta-analysis of the included literature using RevMan 5.3 software.Results A total of 3 088 pediatric patients were ultimately included in 12 studies.Meta analysis showed that the effective rate of traditional Chinese patent medicine was higher than that of the placebo group,with a statistically significant difference [RR=2.06 (1.63,2.62),P<0.000 01].The effective rate of traditional Chinese patent medicine was not significantly different from that of tiapride hydrochloride [RR=1.03 (0.98,1.07),P=0.23].In terms of tic severity,traditional Chinese patent medicine could significantly reduce the total score of YGTSS compared with placebo [MD=-7.84 (-10.18,-5.51),P<0.000 01].Comparing traditional Chinese patent medicine with tiapride hydrochloride,there was no statistically significant difference in the reduction of the total score of YGTSS [MD=-0.32 (-1.21,0.58),P=0.75].In terms of adverse events,the incidence of dizziness,fatigue and sleepiness of traditional Chinese patent medicine was lower than that of tiapride hydrochloride.Conclusion Traditional Chinese patent medicine is effective and safe in the treatment of tic disorders in children,which still needs to be confirmed by more high-quality randomized controlled studies.
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    Chinese Pediatrics of Integrated Traditional and Western Medicine    2010, 2 (1): 56-58.   DOI: 10.3969/j.issn.1674-3865.2010.01.024
    Abstract719)      PDF(pc) (397KB)(4361)       Save
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    Research progress of language development assessment in children
    LIU Fang
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2019, 11 (2): 125-129.   DOI: 10.3969/j.issn.1674-3865.2019.02.009
    Abstract1344)      PDF(pc) (555KB)(4064)       Save

    Language is a cognitive expression that reflects the human brain's thinking and psychological process. Language plays an important role in children's cognitive and social development. Children's language is an important aspect reflecting intelligence. Language development disorders are the most common disorders of childhood development. Early childhood language problems can be used as a vigilance indicator of the brain's overall dysplasia, and can be used as an indicator to predict the cognitive processing obstacles of children's brains now and in the future. Language impaired children routinely need to have their cognitive processing levels detected.
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    Individualized intervention strategies in the treatment of childhood and adolescent obesity based on precision medicine
    LI Ping, YANG Fan, LIU Hanmin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 1-7.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.001
    Abstract3530)      PDF(pc) (1165KB)(3908)       Save
    Childhood and adolescent obesity has become a global challenge in public health.Its high weight regain rate and risks of metabolic complications highlight the limitations of traditional intervention strategies.This review systematically explores individualized intervention strategies for obesity in children and adolescents in the context of precision medicine,breaking the traditional "one-size-fits-all" model.It integrates multi-omics technologies with intelligent management methods,proposing a multidimensional framework for precise intervention.First,a precise diagnosis and evaluation system is constructed based on multi-modal data,including genomics,radiomics,and gut microbiomics,to identify genetic susceptibility,metabolic phenotypes and microbiome characteristics,laying the foundation for stratified interventions.Secondly,individualized intervention plans are developed based on genetic risk scores,epigenetic regulatory mechanisms,and gut microbiome-targeted therapies:gene-guided strategies aim to optimize dietary structure through multi-gene risk assessments; epigenetic interventions aim to regulate DNA methylation and histone modification by taking advantage of nutrients (such as methyl donors and short-chain fatty acids),reversing metabolic dysregulation; microbiome remodeling aims to improve energy metabolism balance through probiotics and synbiotics.Furthermore,artificial intelligence and wearable devices are employed for dynamic monitoring in multiple scenarios.By collaborating with multidisciplinary teams in nutrition,sports medicine,and psychology,a smart management model of "hospital-family-community" network is established.While precision medicine offers groundbreaking directions for childhood obesity treatment,challenges such as biomarker validation,data integration,and long-term efficacy evaluation remain to be addressed.This review provides theoretical foundations and practical pathways for the improvement in the effectiveness and sustainability of interventions,emphasizing the need to integrate interdisciplinary innovative technologies in the future in order to promote the transformation of childhood obesity management toward precision and intelligence.
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    Research progress of Chinese medicine treatment for short stature children
    LIU Feng, YANG Wenxuan, LIU Qiansheng, ZHANG Hui, MA Yanfang
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2020, 12 (2): 128-131.   DOI: 10.3969/j.issn.1674-3865.2020.02.009
    Abstract1380)      PDF(pc) (543KB)(3703)       Save
    This paper mainly makes a retrospective analysis and summary of TCM literature related to dwarfism in the past 10 years,aiming to provide a theoretical basis for TCM diagnosis and treatment of dwarfism.The treatment for dwarfism in TCM includes oral administration of Chinese medicine,acupuncture,massage,acupoint application,etc The curative effect is good,the price is relatively low and there are fewer adverse reactions,so it is worthy of clinical promotion and further study.
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    Analysis of direct medical cost in children with acute lymphocytic leukemia
    YAN Yuzhu, YU Jie, AN Xizhou, GUO Xiaoli, YAO Juan, DENG Zhifen, ZHANG Wenjun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (2): 136-139.   DOI: 10.3969/j.issn.1674-3865.2024.02.008
    Abstract2283)      PDF(pc) (974KB)(3515)       Save
    Objective To analyze the direct medical cost and composition ratio of children with acute lymphocytic leukemia,in order to provide basis for the reform of medical system and guarantee the standard treatment of children with leukemia.Methods A total of 110 children with acute lymphocytic leukemia were included in the study,who were treated in the Department of Hematology Oncology of Children′s Hospital Affiliated to Chongqing Medical University from Jan.2015 to Apr.2018.Descriptive analysis was used to analyze the direct medical costs of these children and investigate the main compositions.Results During the standard treatment of children with acute lymphocytic leukemia,the direct medical costs were mainly composed of outpatient costs (averaged 23 597 CNY),one-day chemotherapy costs averaged 23 216 CNY,hospitalization costs averaged 158 152 CNY.In the total cost of children with ALL,drug costs,treatment costs and laboratory test costs accounted for a large proportion.The average reimbursement rate was 59.1%(93 415/158 152).The average hospitalization time of children with acute lymphoblastic leukemia was 131 days,and the average daily hospitalization cost was 1 207 CNY(158 152/131).Conclusion Reducing drug costs and standardized treatment and testing can reduce medical costs.Comprehensive and multi-angle support should be provided for the families of children with leukemia,in order to guarantee the treatment for these children.
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    Current research of traditional Chinese medicine on ADHD in children
    HAN Xinmin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2016, 8 (5): 465-467.   DOI: 10.3969/j.issn.1674-3865.2016.05.001
    Abstract1598)      PDF(pc) (372KB)(3319)       Save
    In this paper, we analyzed the evolution of TCM name of ADHD, clinical and experimental research, characteristics and advantages,and deficiencies and prospects. Although there are many clinical reports, most of them lack strict design, without multicentric, randomized, controlled and large-sample clinical research. In the recent 10 years, the research projects supported by National Natural Science Foundation of China haven't obtained ground-breaking progress. The advantages of TCM treatment for ADHD are individualized diagnosis and therapy, syndrome differentiation treatment, integral regulation and restoration of the function of the internal organs. In order to make greater innovative achievements, it is necessary to conduct further research and standardize experiment through cooperation.
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    A systematic review of the effectiveness and safety of acupoint application in treating children with cough variant asthma
    LI Panpan, WU Liqun, LU Chen, XU Fangwei, CHENG Yuhang
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (6): 529-536.   DOI: 10.3969/j.issn.1674-3865.2021.06.019
    Abstract951)      PDF(pc) (3158KB)(3133)       Save
    Objective To systematically evaluate the effectiveness and safety of acupoint application in the treatment of children with cough variant asthma.Methods Relevant literatures on acupoint applications in treating cough variant asthma(CVA) in children were retrieved from electronic databases, including China National Knowledge Infrastructure(CNKI), WanFang Database , Chongqing VIP information Chinese scientific journals database(VIP), Chinese Biomedical Literature database(CBM), PubMed, Cochrane Library and EMbase database, from their inception till February 2020. Meta-analysis was conducted after extracting related data from the included studies.Results In total, 18 randomized controlled trials(RCTs) involving 1 407 children were selected for the meta-analysis. The analysis indicated that the total effective rate of acupoint applications in the treatment group was better than that in the control group. In terms of the pulmonary function test and ACT scores, the forced expiratory volume in one second(FEV1), forced expiratory volume in one second/forced vital capacity(FEV1/FVC), peak expiratory flow rate(PEF) and ACT scores were better in the treatment group than in the control group. Concerning immune function, IgM, IgG, and IgA values in the treatment group were significantly higher than those in the control group, while IgE values of treatment group were significantly lower. In terms of efficacy in the long run, the treatment group had lower rate of recurrent cough variant asthma and shorter duration spent in eliminating recurrent cough as compared to the control group. The differences in the above research results were statistically significant(P<0.05).Conclusion Acupoint applications can improve the overall efficacy of treatment in children with CVA, improve pulmonary ventilation, boost immunity, and reduce recurrence rate and shorten the duration spent in eliminating recurrent cough.
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    Research progress on the cause and treatment of perianal abscess and anal fistula in children
    LIU Meifang, ZHAO Bin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (2): 121-124.   DOI: 10.3969/j.issn.1674-3865.2023.02.006
    Abstract1057)      PDF(pc) (771KB)(2996)       Save
    Perianal abscess and anal fistula are common perianal diseases in children under 1 year of age, and currently there is no unified understanding about the pathogenesis or unified treatment plans. This paper discusses the causes of perianal abscess and anal fistula in infants based on traditional Chinese medicine and modern medicine, and explores the treatment progress from the aspects of conservative treatment and surgical treatment.
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    Chinese Pediatrics of Integrated Traditional and Western Medicine    2013, 5 (4): 292-294.   DOI: 10.3969/j.issn.1674-3865.2013.04.002
    Abstract722)      PDF(pc) (464KB)(2875)       Save
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    Research progress of tic disorder in children
    WANG Shiyan, MA Bingxiang, LI Ruixing, XU Pingping
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (4): 297-296.   DOI: 10.3969/j.issn.1674-3865.2021.04.005
    Abstract904)      PDF(pc) (768KB)(2551)       Save
    Tic disorder(TD) is acommon sudden, rapid, recurrent neuropsychiatric disorder dominated by rhythmic movement or vocalization in children or adolescents. The exact etiology and pathogenesis are not clear. A small number ofchildren can get relieved by themselves at puberty, but the disease may be refractory in some children. This paper focuses on theresearch frontier of tic disorder at home and abroad. By searching Pubmed, Cochrane Library, CBM, CNKI and Wanfang databases, this paper systematically discusses the diagnosis, treatment and prognosis of ticdisorder from the aspects of epidemiology, comorbidity, pathogenesis and diagnosis and treatment methods by traditional Chinese and Western medicine, in order to provide new treatment ideas and theoretical basis for clinical practice.
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    Exploring the rehabilitation,diagnosis and treatment of autism spectrum disorder in traditional Chinese medicine based on Professor Xu Rongqians "Theory of Shen,Hun,Yi,Po,Zhi"

    ZHU Ling, YU Minfeng, LIU Zhenhuan, LI Nuo, LIU Ying, LI Longhua, HUANG Yinying, LIN Xiaohong, CHEN Kanghua
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 333-338.   DOI: 10.3969/j.issn.1674-3865.2024.04.013
    Abstract1060)      PDF(pc) (1117KB)(2515)       Save
    The occurrence of autism spectrum disorder (ASD) involves multiple organ dysfunction.Professor Xu Rongqian′s "Theory of Shen,Hun,Yi,Po,Zhi" can explain various core clinical manifestations of ASD.Through in-depth analysis of the functions of Shen,Hun,Yi,Po,Zhi,it has been discovered that the occurrence of this disease is closely related to the "Five Organs Shen",especially to the heart-Shen,liver-Hun,spleen-Yi,and kidney-Zhi.The theoretical system of "treatment for both Xing and Shen" is used in clinical practice to guide the treatment of ASD,which achieves good therapeutic effects by benefiting Xing and qi.
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    Treatment for pediatric pulmonary diseases based on the theory of "lungs governing skin and hair" and the method of "analogy and classification" 
    WEI Jiaxuan, YANG Jianhui, FENG Zhongfa, LI Rong, ZHAO Shun, LIU Qiaoya
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 75-78.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.016
    Abstract2777)      PDF(pc) (1062KB)(2502)       Save
    This paper explores the application value of Traditional Chinese Medicine (TCM) theory of "lungs governing skin and hair" and the thinking method of "analogy and classification" in the treatment of pediatric pulmonary diseases.Both "lungs governing skin and hair" and "analogy and classification" are traditional TCM theoretical approaches guiding clinical differential diagnosis and treatment.By discussing the correlation between the lungs and the skin and hair,and then employing the method of analogy and classification,this paper explores the feasibility and efficacy of treating pulmonary diseases by the "skin"-cortex (the character of skin and cortex is the same in Chinese).Starting from the physiological characteristics of children,such as "lung deficiency" and loose cutaneous layers,the paper argues that "cortex-related" herbal medicines (e.g.,Baixian Pi,Hou Po,and Chan Tui) can improve the pathological features of being easily invaded by external pathogens in children.Through case studies,this paper demonstrates a formula containing cortex-related herbs in the treatment of cough (wind-phlegm obstructing the lung) in a 4-year-old child,which is very effective.The results confirm the clinical feasibility of this approach.By integrating traditional TCM theories with modern scientific validation,this paper provides new insights into the diagnosis and treatment of pediatric pulmonary diseases,highlighting the unique advantages of TCM in the field of pediatrics.
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    New progress and clinical application of allergen detection
    LI Yixian, YANG Jun, XIA Yu
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2021, 13 (2): 117-.   DOI: 10.3969/j.issn.1674-3865.2021.02.007
    Abstract1328)      PDF(pc) (626KB)(2453)       Save
    Allergen detection is an important method in the diagnosis and evaluation of allergic diseases.Classical detection methods such as skin tests and IgE in vitro tests are developing in the direction of more allergens,less blood samples and higher accuracy;meanwhile,the new detection like cellular and molecular diagnosis are developing rapidly.In order to provide better clinical decision making for clinicians who are facing complicated detection methods,this article reviews the common allergen detection methods in vivo and in vitro,introduces their indications,advantages and disadvantages as well as their clinical application in various types of allergic diseases and different groups of people.
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    Research progress of vestibular rehabilitation training for children with cerebral palsyYU Chaonan
    YU Nan, LI Dongxiao, WAN Kai, SHANG Qing
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2022, 14 (6): 468-472.   DOI: 10.3969/j.issn.1674-3865.2022.06.002
    Abstract1041)      PDF(pc) (832KB)(2447)       Save
    Cerebral palsy is a group of syndromes characterized by movement disorders,abnormal posture,musclestrength and muscle tension changes. The main function of the vestibular system is to maintain the stability of the head and trunk,maintain body balance and motor coordination. The vestibular function damage of children with cerebral palsy can lead to impaired balance function,poor posture control,difficulty in eye movement,poor head-eye coordination and delayed motor development. Vestibular rehabilitation training is an individualized non-drug rehabilitation treatment, which,mainly through vestibular adaptation,vestibular acclimatization,vestibular compensation and other mechanisms and through repeated strengthening of vestibular receptors,improves the excitability of nerve cells and promotes the injury of brain tissue area to produce new neural pathways,so as to effectively improve the patient′s motor function,posture control,balance ability,muscle strength and muscle tension,eye movement and so on. At present,vestibular rehabilitation training has been widely used in adults with Parkinson′s disease,stroke,spinal cord injury,Alzheimer′s disease. It has also been used in children with autism spectrum disorder,attention deficit hyperactivity disorder,and global developmental delay. There are few reports on the effects of vestibular rehabilitation training on children with cerebral palsy. Based on the above background,this paper summarizes the vestibular rehabilitation training mechanism of vestibular rehabilitation training in the treatment of children with cerebral palsy at home and abroad,in order to provide help for better improving the quality of life of children with cerebral palsy.
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    Exploring the pathogenesis of pediatric functional dyspepsia based on the theory of "spleen deficiency as the root"
    WANG Na, LIU Shiyu, LIU Jie, YU Jian, XIONG Lei
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (6): 477-481.   DOI: 10.3969/j.issn.1674-3865.2024.06.004
    Abstract1787)      PDF(pc) (1035KB)(2438)       Save
    Functional dyspepsia(FD) is a common chronic gastrointestinal disorder in children,characterized by symptoms such as upper abdominal discomfort,abdominal distension,poor appetite,and acid regurgitation.The pathogenesis of FD is complex,involving multiple factors such as gastrointestinal motility disorders,visceral hypersensitivity,and brain-gut axis dysfunction.In traditional Chinese medicine (TCM),it is believed that the theory of "spleen deficiency as the root" is the core pathological mechanism.Specifically,spleen deficiency impairs the normal flow of qi,leading to the accumulation of dampness and stagnation,which brings about gastrointestinal motility issues and visceral hypersensitivity.Furthermore,spleen dysfunction weakens qi and hinders digestive absorption and blood production,worsening gut microbiota imbalances and disrupting brain-gut axis regulation.The TCM treatment strategy for FD involves four key approaches:strengthening the spleen,regulating spleen qi,activating spleen function,and balancing qi flow.Strengthening the spleen and eliminating dampness enhances gastrointestinal motility and removes stagnation.Regulating spleen qi improves digestion and relieves food retention.Activating spleen function restores healthy digestion and absorption.Balancing qi flow ensures smooth coordination of qi ascending and descending to relieve stagnation.These TCM methods align closely with modern medical strategies of regulating gastrointestinal motility,reducing visceral hypersensitivity,and balancing brain-gut axis.This study systematically explores the pathogenesis of FD and the treatment strategy of integrating TCM with modern medicine from the perspective of "spleen deficiency as the root".It highlights the intricate interactions among spleen function,the brain-gut axis,and gut microbiota.This research provides theoretical foundation and guidance for the treatment of children with FD.
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    A network Meta-analysis of the clinical efficacy of guideline-recommended external treatment of traditional Chinese medicine for anorexia in children
    Zhonghe ZENG, Longming LEI, Jun ZHAO, Qiongxiao WANG, Lin FU, Mengyun WU, Danlu SU, Guanghui CHEN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (1): 23-30.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.01.005
    Abstract1605)   HTML2)    PDF(pc) (1069KB)(2323)       Save

    Objective To evaluate the efficacy and safety of guideline-recommended non-pharmacological TCM therapies for pediatric anorexia via a network Meta-analysis. Methods RCTs from CNKI, Wanfang, PubMed, Web of Science, Embase, and Cochrane Library up to March 2025 were searched. Quality assessment used ROB 2.0,and data were analyzed with Stata 18.0. Results Thirty-eight RCTs (3 546 patients) covering pricking at Sifeng points, acupoint application, pediatric Tuina, and their combinations were included. Pricking at Sifeng points+pediatric Tuina was most likely the best intervention for overall clinical effectiveness(SUCRA=78.9%) and serum zinc improvement(SUCRA=95.1%).Pediatric Tuina+oral medication ranked highest for improving serum iron(SUCRA=85.7%) and serum calcium(SUCRA=83.4%). Conclusion Pricking at Sifeng points plus pediatric Tuina is recommended for overall efficacy and serum zinc, while pediatric Tuina with oral medication performs better for serum iron and calcium. Therapy selection should be individualized based on serological indicators. Further high-quality RCTs are warranted.

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    Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution
    WANG Qi, WANG Xuefeng, ZHAO Xia, LI Min
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (4): 277-282.   DOI: 10.3969/j.issn.1674-3865.2023.04.001
    Abstract1780)      PDF(pc) (857KB)(2319)       Save
    Expert consensus on body constitution characteristics and nursing of children in traditional Chinese medicineBody Constitution Research Committee of World Federation of Chinese Medicine Societies
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